Caspofungin Acetate Cancidas CAS 179463-17-3 API Nadaafadda Sare ee Warshada
Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Caspofungin Acetate
CAS: 179463-17-3
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Caspofungin Acetate |
La mid ah | Kansarka;MK-0991 Acetate;L-743872 Acetate |
Lambarka CAS | 179463-17-3 |
Lambarka CAT | RF-API58 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C52H88N10O15·2C2H4O2 |
Miisaanka Molecular | 1213.42 |
Meesha dhalaalaysa | >197 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama ku dhawaad cad |
Aqoonsiga IR | IR: Spectrum ee muunada Imtixaanku waa in uu waafaqo kan Caspofungin Acetate Standard Reference |
Aqoonsiga HPLC | HPLC: Waqtiga haynta ee mabda'a ugu sarreeya ee laga helay xalka tijaabada waa inuu waafaqo kan laga helay xalka caadiga ah, sida tijaabada Assay |
Cadaynta iyo Midabka | Xalku waa inuu noqdaa mid cad oo aan midab lahayn |
Wareeg gaar ah | -102.0° ~ -108.0° |
pH | 5.0 ~ 7.0 |
Biyo | ≤10.0% |
Walxaha laxidhiidha I | (oo ku salaysan Anhydrous iyo Acid Acid Bilaashka ah) |
Xumaanta A | ≤0.10% |
Xumaanta B | ≤0.10% |
Xumaanta D | ≤0.30% |
Xumaanta E | ≤0.10% |
Xumaanta Aan La cayimin F | ≤0.10% |
Xumaanta Aan La cayimin G | ≤0.10% |
Pneumocandin B0 | ≤0.10% |
Xumaanta Keliya Aan La Aqoon | ≤0.10% |
Wadarta wasakhda | ≤1.0% |
Walxaha La Xiriira II | ≤0.10% |
Xalalka Haraaga ah | |
Ethyl acetate | ≤5000ppm |
Ethanol | ≤5000ppm |
Methanol | ≤5000ppm |
Acetonitrile | ≤410pm |
Tetrahydrofuran | ≤720pm |
Waxa ku jira Asiidh Asiidh | 9.0% ~ 11.0% (Waxaa lagu xisaabiyaa ku saleysan Anhydrous) |
Ethylendiamine | ≤0.10% |
Hadhaaga dabka | ≤0.10% |
Biraha culus (sida Pb) | ≤10pm |
Habka Qiimaynta / Falanqaynta | 97.0% ~ 102.0% (Ku salaysan Anhydrous iyo Solvent Free) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Caspofungin Acetate (CAS: 179463-17-3) waa daawada fangaska ee lipopeptide.Caspofungin acetate ee duritaanka waxaa asal ahaan ansixisay FDA gudaha Mareykanka, iyo EMEA ee Yurub, 2001. Caspofungin Acetate waa biyo milmay, xasilloon, aza-beddelay derivative semisynthetic Pneumocandin B, wax soo saarka halsano ee fangaska Zalerion arboricola.Lipopeptide caspofungin, waxay joojisaa isku-darka 1,3-beta-D-glucans ee ku jira kaliya derbiga unugyada fangas, taas oo keenta lysis gaar ah ee unugyada pathogenic.Xaruntu waa fungicidal halkii ay ka ahaan lahayd fungistatic, oo ah muuqaal aan caadi ahayn oo ka mid ah wakiilada antifungal.Caspofungin guud ahaan wuu ka firfircoonaa amphotericin B, flucytosine, fluconazole iyo itraconazole lidka ku ah noocyada Candida.