Microcrystalline Cellulose (MCC) CAS 9004-34-6 Assay 97.0 ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee Microcrystalline Cellulose (MCC) (CAS: 9004-34-6) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso Microcrystalline Cellulose,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Microcrystalline cellulose |
| La mid ah | MCC;Cellulose Microcrystalline;Cellulose;Budada Cellulose;α-cellulose |
| Heerka Saamiyada | Kaydka dhexdiisa, Awood Wax-soo-saar 6500 Ton sannadkii |
| Lambarka CAS | 9004-34-6 |
| Qaanuunka molecular | (C6H10O5) n |
| Miisaanka Molecular | 162.06 g/mol |
| Meesha dhalaalaysa | 76.0 ~ 78.0 ℃ |
| Barta Fiishka | 164℃ |
| Cufnaanta | 1.5 g/cm3 (20 ℃) |
| Tusmada N20/D | 1.504 |
| ur | Aan ur lahayn |
| Xasilooni | DegganGubi karaAan ku habboonayn Wakiilada Oxidaynta Xoogan |
| Heerkulka Kaydinta | Ku kaydi heerkulka qolka, qabow oo qallaji |
| COA & MSDS | La heli karo |
| Asal ahaan | Shiinaha |
| Summada | Kiimikada Ruifu |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Budada cad ama Off-Cad | U hogaansama |
| Solubility | Aan ku milmin Biyaha, Ethanol, Acetone, ama Toluene | U hogaansama |
| Qaybinta Cabbirka Walxaha (+60 Mesh) | 0-10% | U hogaansama |
| Qaybinta Cabbirka Walxaha (+200 mesh) | 40-100% | U hogaansama |
| Walxaha Biyaha ku milmi kara | ≤0.25% | 0.015% |
| Walxaha Eter-Sooluble | ≤0.05% | <0.05% |
| Qiimaha pH | 5.0 ~ 7.5 | 5.3 |
| Chloride (Cl) | ≤0.03% | <0.03% |
| Istaarij | Waa in aanu muujin Buluug | U hogaansama |
| Khasaare xagga qalajinta | ≤7.0% | 3.4% |
| Hadhaaga dabka | ≤0.10% | <0.10% |
| Biraha culus (Pb) | ≤10pm | <10pm |
| Arsenic (As) | ≤2pm | <2pm |
| Sodium Carboxymethyl Cellulose | 10.0 ~ 20.0% | U hogaansama |
| Xadka Microbial | ||
| Wadarta tirada Microbial Aerobic | ≤1000 cfu/g | <10 cfu/g |
| Wadarta caaryada iyo khamiirka | ≤100 cfu/g | <10 cfu/g |
| Escherichia Coli | Lama ogaan /10g | U hogaansama |
| Salmonella | Lama ogaan /10g | U hogaansama |
| Qiimayn | 97.0 ~ 102.0% | 98.0% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabta waa la tijaabiyay oo waafaqay qeexitaannada | |
Xidhmada:Dhalo, 25kg/bac kraft, 25kg/dub fiber, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weel si adag u xiran.Ku kaydi bakhaar qabow, qalalan oo hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka fogow soo-gaadhista kulaylka xad dhaafka ah.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Microcrystalline cellulose
Cellulose [9004-34-6].
Qeexitaan
Microcrystalline Cellulose waa la nadiifiyaa, cellulose qayb ahaan depolymerized ah oo lagu diyaariyey daawaynta alfa cellulose, oo laga helay saxarka walxaha dhirta fayraska leh, oo leh acids macdanta.
AQOONSIGA
A. Habka
Xalka zinc chloride oo la ureeyay: Ku mil 20 g oo zinc chloride ah iyo 6.5 g oo potassium iodide ah 10.5 ml oo biyo ah.Ku dar 0.5 g oo iodine ah, oo rux ilaa 15 daqiiqo.
Tusaale: 10 mg
Falanqaynta: Dhig muunada muraayadda saacadda, oo ku kala firdhi 2 ml oo ah zinc chloride oo iodine leh.
Shuruudaha aqbalaadda: Walaxda waxay qaadataa midab buluug-violet ah.
B. Habka
Tusaalaha: 1.3 g oo ah Microcrystalline Cellulose, oo si sax ah loo miisaamay ilaa 0.1 mg
Falanqaynta: Ku beddel muunadda ilaa 125-mL weel.Ku dar 25.0 ml oo biyo ah iyo 25.0 ml oo ah 1.0 M cupriethylenediamine hydroxide xal.Isla markiiba ku nadiifi xalka nitrogen, geli joojiyaha, oo ku rux ruxruxiyaha gacanta, ama ruxruxiyaha kale ee farsamada ee ku habboon, ilaa uu si buuxda u milmo.Ku wareeji mugga ku habboon ee xalka Tusaalaha oo aad u gudbiso nambar la cabbiray 150 Cannon-Fenske, ama u dhigma, viskometer.U ogolow in xalku isu simo 25 ± 0.1 ee NLT 5 min.Wakhtiga socodka u dhexeeya labada calaamadood ee viskometerka, oo qor wakhtiga socodka, t1, in s.
Xisaabi viscosity kinematic, (KV)1, ee Microcrystalline Cellulose ee la qaaday:
Natiijada= t1 × k1
t1= wakhtiga socodka
k1= viscometer joogto ah (eeg Viscosity 911)
Hel wakhtiga socodka, t2, ee 0.5M cupriethylenediamine hydroxide xalalka adoo isticmaalaya nambar 100 Cannon-Fenske, ama u dhigma, viscometer.
Xisaabi viscosity kinematic, (KV)2, ee dareeraha:
Natiijada= t2 × k2
t2= wakhtiga socodka 0.5M cupriethylenediamine hydroxide xal (s)
k2= viscometer joogto ah
Go'aami viscosity qaraabo, rel, ee muunada Microcrystalline Cellulose ee la qaaday:
Natiijadu= (KV)1/(KV)2
(KV) 1= viscosity kinematic of Microcrystalline Cellulose la qaatay
(KV)2=muwadigii kinematic ee dareeraha
Go'aami viscosity-ka gudaha, []c, is dhexgal, addoo isticmaalaya Shaxda Viscosity Intrinsic ee qaybta Miisaska Tixraaca.
Xisaabi heerka polymerization, P:
Natiijadu= (95) × [η]c/WS × [(100%LOD)/100]
[η]c= viscosity gudaha
WS= miisaanka Microcrystalline Cellulose ee la qaaday (g)
%LOD=qiimaha laga helay baadhista luminta qalajinta
Shuruudaha aqbalaadda: Heerka polymerization kama weyna 350.
XANUUNKA
wasakhda aan noolaha ahayn
• Hadhaaga dabka 281: NMT 0.1%
• Biraha culus, Habka II 231: NMT 10 ppm
IMTIXAANO GAAR AH
• Tijaabooyin Tiro-koobeedka Microbial 61 iyo Tijaabooyin Ku Saabsan noole-yeerayaasha 62: Wadarta tirada microbial aerobic kama badna 1000 cfu/g, wadarta guud ee caaryada iyo tirooyinka khamiirkuna kama badna 100 cfu/g.Waxay buuxisaa shuruudaha imtixaannada maqnaanshaha Staphylococcus aureus iyo Pseudomonas aeruginosa iyo maqnaanshaha Escherichia coli iyo noocyada Salmonella.
• Hab-dhaqanka
Tusaale: 5 g
Falanqaynta: Ku rux Muunaha 40 ml oo biyo ah 20 daqiiqo, iyo centrifuge.Hayso tamarta sare si loogu isticmaalo tijaabada pH.Isticmaalka mitirka conductivity kaha ku haboon oo lagu jaangooyey heerka cabirida koloride potassium oo leh 100 µS/cm, cabbir dhaqdhaqaaqa tamarta sare ka dib marka la helo akhrin deggan, oo cabbir dhaqdhaqaaqa biyaha loo isticmaalo diyaarinta tijaabada muunad.
Shuruudaha aqbalaadda: Daawashada tamarta sare kama badna socodka biyaha in ka badan 75 µS/cm.
pH 791: 5.0-7.5 ee heerka sare ee laga helay tijaabada akhlaaqda
731: Qalaji muunad 105 ilaa 3 saacadood: waxay luminaysaa NMT 7.0% miisaankeeda, ama boqolkiiba kale oo hoose, ama waxay ku jirtaa xadka boqolkiiba, sida lagu qeexay calaamadaynta.
• Cufnaanta Bulk
Falanqaynta: Isticmaal mugga cabirka lagu rakibay shaashad 10-mesh ah.Volumeter-ku waxa uu xor u yahay koobka naxaasta ah ama birta aan lahayn, kaas oo lagu cabbiray awood dhan 25.0 ± 0.05 mL oo leh dhexroor gudaha ah 30.0 ± 2.0 mm.Miisaanka koobka madhan, dhig godka hoostiisa, oo si tartiib ah ugu shub budada dhererka 5.1 cm (2 in) ee ka sarreeya funnelka iyada oo loo marayo mugga cabbirka, qiyaasta ku habboon si looga hortago in la xiro, ilaa koobku ka buuxo.[Xusuusin-Haddii shaashadu xidhmo xad dhaaf ah ay dhacdo, ka saar shaashadda.] Heerka budada xad dhaafka ah, oo miisaan koobka buuxsan.Xisaabi cufnaanta bulk adigoo u qaybinaya miisaanka budada koobka ku jira mugga koobka.
Shuruudaha aqbalaadda: cufnaanta badnidu waxay ku dhex jirtaa qeexida calaamadeysan.
• Qaybinta Cabbirka Qaybaha
[Xusuusin-Xaaladaha aysan jirin wax walaac ah oo la xidhiidha shaqeynta oo laxiriirta qaybinta qaybinta maqaalka, tijaabadan waa laga saari karaa.]
Halka calaamadaynta ay sheegayso qaybinta cabbirka walxaha, go'aami qaybinta cabbirka qaybinta sida lagu farayo Qiyaasta Qaybinta Qaybinta Qaybinta ee Sieving 786, ama habraac habboon oo la ansaxiyay.
• Walxaha Biyaha-Luulaya
Tusaale: 5.0 g
Falanqaynta: Ku rux Muunaha 80 mL oo biyo ah 10 daqiiqo, oo ku gudub adiga oo isticmaalaya faakuum warqad shaandhaysa (Whatman No. 42 ama u dhigma) gal faaruq ah.Ku wareeji shaandhaynta ilaa digsi la jarjaray, uumi-bax qallayl la'aan, ku engeji 105 ilaa 1 saac, ku qabooji qalajiyaha, oo miisaan.
Shuruudaha aqbalaadda: Farqiga u dhexeeya miisaanka haraaga iyo miisaanka laga helay go'aaminta bannaan kama badna 12.5 mg (0.25%).
• Walxaha Eter-Sooluble
Tusaale: 10.0 g
Falanqaynta: Ku rid muunada tiir-chromatographic leh dhexroor gudaha ah oo qiyaastii ah 20 mm, oo dhex mari 50 ml oo ah eter-free peroxide tiirka.Uumi-baxa si uu u engego saxan hore u engejiyey oo la gooyey adiga oo la kaashanayo hawo hadda ku jirta dabool qiiq ah.Ka dib marka dhammaan etherku uumi baxo, qalaji hadhaaga 105 ilaa 30 daqiiqo, ku qabooji qalajiyaha, oo miisaan.
Shuruudaha aqbalaadda: Farqiga u dhexeeya miisaanka haraaga iyo miisaanka laga helay go'aaminta bannaan kama badna 5.0 mg (0.05%).
SHURUUD DHEERAAD AH
Baakadaha iyo Kaydinta: Ku kaydi weelal cidhiidhi ah.
• Calaamadaynta: Calaamadaynta waxay muujinaysaa khasaaraha magaca ah ee qalajinta, cufnaanta badan, iyo heerka qiyamka polymerization.Heerka u hoggaansanaanta polymerization-ka waxaa lagu go'aamiyaa iyadoo la adeegsanayo Tijaabada Aqoonsiga B. Halka qaybinta cabbirka qaybinta lagu sheegay calaamadaynta, u wad sida lagu faray tijaabada Qaybinta Cabbirka Qaybaha.Calaamadinta ayaa tilmaamaysa farsamada cabbirka qaybinta qaybinta lagu go'aamiyay haddii farsamo aan ahayn shaandhayn gorfayneed la isticmaalay;iyo calaamadaynta waxay muujinaysaa d10, d50, iyo d90 qiyamka iyo inta u dhaxaysa mid kasta.
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Microcrystalline Cellulose (MCC) (CAS: 9004-34-6) waa cellulose la safeeyey, qayb ahaan depolymerized taas oo u dhacda sida cad, ur aan lahayn, dhadhamin, budo crystalline ka kooban qaybo dalool ah.Waxa ganacsi ahaan lagu heli karaa cabbirro kala duwan iyo heerar qoyaan oo leh sifooyin iyo codsiyo kala duwan.
Microcrystalline Cellulose waxaa inta badan loo isticmaalaa sida cuntada lagu daro non-caloric, excipients farmashiyaha iyo kala firdhiyey, chromatography lakabka khafiif ah iyo xirmada chromatography column, midabaynta for dheeha iyo pigments, xoojinta buuxinta for resins heerkulbeeg iyo heerkulbeegyada laminates, dahaarka, emulsifiers, sidoo kale waa la isticmaali karaa. rinjiga biyaha ku salaysan iyo warshadaha dhoobada.
Budada cellulose daahirnimo sare leh ee chromatography qaybta.
Cellulose waa dhumuc iyo emulsifier.Cellulose (microcrystalline) waxaa loo isticmaalaa sidii emulsifier ee kiriimyada la isku qurxiyo.
Microcrystalline Cellulose waxaa si weyn loogu isticmaalaa cuntada sida wakiilka ka hortagga-caking, stabilizer, aan macquul ahayn, wakiilka xira, fiber la cuni karo iwm.
Ku habboon dunta, dharka, wax-samaynta, cuntada, waraaqaha iyo warshadaha kale.
Microcrystalline Cellulose waxaa loo isticmaali karaa sida wakiilka ka hortagga, emulsifier, kala firdhiye, iyo xiraha."Heerarka Nadaafadda ee Isticmaalka Cunnada Lagu daro" (GB2760-2011) ee waddankeyga ayaa qeexaya in loo isticmaali karo budada iyo kareemka aan caanaha ahayn, oo leh qiyaasta isticmaalka ugu badan ee 20g/kg;loogu talagalay jalaatada, 40g / kg;cuntooyinka faybarku ku badan yahay iyo rootiga, 20g/kg.Tixraaca kale ee isticmaalka: Isticmaalka jalaatada waxay wanaajin kartaa saamaynta guud ee emulsification, ka hortagga samaynta barafka, iyo hagaajinta dhadhanka.Marka lagu daro carboxymethyl cellulose waxay kordhin kartaa joojinta budada kookaha ee cabitaanada caanaha...
Microcrystalline Cellulose waxay leedahay faa'iidooyinka cufnaanta hoose, modules sare, la cusboonaysiin karo, la dumin karo iyo ilo ballaaran.Waxaa loo isticmaali karaa sida wakiilka xoojinta si loo hagaajiyo sifooyinka isku dhafan.
Microcrystalline Cellulose waa saldhig cunto oo muhiim ah oo ka shaqeeya warshadaha cuntada - cellulose cuntada, wax lagu daro cunto caafimaad oo ku habboon;loo isticmaalo warshadaha dahaarka Sifooyinkiisa thixotropic iyo dhumucdiisuna waxa loo isticmaali karaa sidii dhumuc iyo emulsifier ee rinji ku salaysan biyaha;waa nooc ka mid ah buuxinta, dhumucyada iyo emulsification ee alaabta la isku qurxiyo, waxayna leedahay awood ku-meel-gaar ah oo wanaagsan oo ah walxaha saliidda leh;Loo isticmaalo dhumucdi iyo buuxinta soo saarista maqaar macmal ah, maqaar macmal ah ayaa siman oo lebbisan dhumucda.Waxaa la arki karaa in isticmaalka microcrystalline cellulose uu yahay mid aad u ballaaran, iyo baahida badeecadan ee Shiinaha ayaa sii wadi doonta inay kordhiso.
Microcrystalline Cellulose waa guban kara.Aan ku habboonayn walxaha oksaydhka ee xooggan oo ay ku jiraan bromine pentafluoride, sodium nitrate, fluorine, perchlorates, perchloric acid, chlorate sodium, magnesium perchlorate, F2, permanganate zinc, nitrite sodium, nitrate sodium, sodium peroxide.Nitrate-ka isku jira nitric iyo sulfuric acids waxay soo saartaa nitrate-ka Cellulose microcrystalline (celluloid pyroxylin, pyroxyline milmi leh, guncotton) kuwaas oo guban kara ama qarxa.
Cellulose waa mid aan firfircoonayn waxaana loo kala saaraa sidii boodh dhib leh.Waxay leedahay wax yar, haddii ay jirto, saameyn xun oo ku saabsan sambabada, mana jiraan warbixinno ku saabsan cudurka dabiiciga ah ama saameynta sunta ah.Saamaynta caafimaad ee loo aaneeyo alwaaxda, suufka, flax, jute, iyo hemp looma nisbayn karo waxa ku jira cellulose laakiin halkii ay joogaan walxo kale.Fiilooyinka cellulose ayaa laga helay dhiigga iyo kaadida tabaruceyaasha bini'aadamka oo quudin jiray cellulose midabaysan;ma jirin saameyn xun.
Microcrystalline Cellulose iyo carboxymethylcellulose sodium waxaa loo isticmaalaa in lagu soo saaro jel thixotropic ku haboon sida hakin baabuurta ee hababka dawooyinka iyo qurxinta.Sodium-carboxymethylcellulose waxay caawisaa kala firdhinta waxayna u adeegtaa sidii kolloid ilaalin ah.Isku-ururinta wax ka yar 1% adkaha waxa ay soo saartaa dareeraha dareeraha ah, halka isku-ururinta in ka badan 1.2% adkaha ay soo saaraan jel-dabiiciga thixotropic.Marka si sax ah loo kala firdhiyo, waxay siisaa xasiloonida emulsion, indho-furnaanta iyo joojinta badeecadaha kala duwan, waxaana loo isticmaalaa buufinta sanka, buufinta jirka la mariyo iyo kareemka, ka joojinta afka, emulsions, kiriimyada iyo jel.
Boodh dhib leh.Marka loo kululeeyo si uu u burburo waxay soo daysaa qiiq qallafsan iyo qiiq xanaaq badan.
Microcrystalline Cellulose waxaa si weyn loogu isticmaalaa dawooyinka afka laga qaato iyo alaabta cuntada waxaana guud ahaan loo arkaa wax aan sun ahayn oo aan dhib lahayn.Microcrystalline cellulose looma nuugo si nidaamsan ka dib maamulka afka sidaas awgeedna wax yar oo sun ah ayaa leh.Isticmaalka xaddi badan oo cellulose ah ayaa laga yaabaa inay yeelato saameyn calool jilciye ah, inkastoo tani aysan u badneyn inay dhibaato noqoto marka cellulose loo isticmaalo dawooyinka dawooyinka.Ku xadgudubka ula kac ah ee qaababka ay ku jirto cellulose, ha ahaato neefsashada ama duritaanka, waxay keentay samaynta granulose cellulose.
Microcrystalline Cellulose kuma habboona maaddooyinka oksaydhaynta ee xooggan.
Microcrystalline Cellulose iyo karboxymethylcellulose sodium waa isku dhaf ah laba walxood oo labadaba guud ahaan loo arko kuwa aan sun ahayn: Microcrystalline Cellulose GRAS oo liiska ku jira.Laga aqbalay in loogu isticmaalo sidii cunto lagu daro Yurub dhexdeeda.Waxaa ku jira kaydka macluumaadka ee walxaha aan firfircoonayn ee FDA (neefsashada; kaabsal afka laga qaato, budada, ka joojinta, sharoobada, iyo kiniiniyada; diyaargarowga jirka iyo siilka).Waxaa ku jira dawooyinka aan waalidnimada lahayn ee shatiga ku leh UK.Lagu daray Liiska Kanadiyaanka ee Walxaha aan Dawaynta ahayn ee La Aqbali Karo.Carboxymethylcellulose sodium GRAS ayaa ku taxan.Laga aqbalay cunto lagu daro Yurub dhexdeeda.Waxaa ku jira Database-ka Walxaha Aan Dhaqdhaqaaqa lahayn ee FDA (Diyaarinta ilkaha; Intra-articular, intrabursal, intradermal, intralesional, iyo intrasynovial cirbadaha; dhibcaha afka, xalalka, ka joojinta, sharoobada iyo kiniinnada; diyaarinta jirka).Waxaa ku jira dawooyinka aan waalidnimada lahayn ee shatiga ku leh UK.Lagu daray Liiska Kanadiyaanka ee Walxaha Dawooyinka Aan La Aqbali karin.
