Cetrorelix Acetate CAS 130143-01-0 GnRH antagonist Peptide Purity (HPLC) ≥98.0% Tayada Sare
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee Cetrorelix Acetate (CAS: 130143-01-0) oo leh tayo sare leh.Cetrorelix Acetate waa hormoonka sii daaya gonadotropin (GnRH) antagonist.Kiimikada Ruifu waxay bixisaa taxane ah peptides GMP.Ruifu waxa uu bixin karaa keenista aduunka oo dhan, qiimo tartan ah, tiro yar iyo tiro badan oo la heli karo.Iibso Cetrorelix Acetate,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Cetrorelix acetate |
| La mid ah | N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate |
| Tixraacyo | Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2 |
| Lambarka CAS | 130143-01-0 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Kiiloogaraam |
| Qaanuunka molecular | C70H92N17O14 |
| Miisaanka Molecular | 1551.16 |
| Heerkulka Kaydinta | Qabow & Meel Qalalan (-20 ℃).Qaboojiyaha |
| Nolosha shelf | >2 sano haddii si habboon loo kaydiyo |
| Qaybta | GMP Peptides |
| Dukumeenti | COA, MS, HPLC, NMR, MSDS, iwm. |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Cad |
| Peptide Purity (waxaa qoray HPLC) | ≥98.0% (oo ah isdhexgalka aaga) |
| Waxa ku jira Peptide | ≥80.0% (by %N) |
| Halabuurka Amino Acid | 10% ee Aragtida |
| Waxyaabaha Acetate | ≤10.0% (waxaa qoray HPLC) |
| Waxyaabaha ay ka kooban tahay TFA | ≤1.0% |
| Xumaanta Keliya | ≤1.0% (waxaa qoray HPLC) |
| Waxyaabaha Biyaha ka kooban (Karl Fischer) | ≤8.0% |
| Qiimayn | 95.0 ~ 105.0% (Waxaa leh Anhydrous, Acid Acid-free) |
| MS | Joogta ah |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Shuruudaha Rarida | Bacaha Barafka, Bacaha qallajiya |
| Asal ahaan Alaabta | Synthetic |
| Fiiro gaar ah | Kaliya Cilmi-baaris, Maaha Isticmaalka Aadanaha |
| Isticmaalka | Ka-hortagayaasha synthetic ee qaabilaadda GnRH |
Xidhmada:Fiilada caaga ah (oo loogu talagalay xirmooyinka peptide) ama dhalo dhalada ah, tirada sida waafaqsan shuruudaha tafatirka macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xidhan meel qabow oo engegan (2 ~ 8℃) bakhaar ka fog walxaha aan ku haboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Gaarsiiya adduunka oo dhan FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Cetrorelix Acetate (CAS 130143-01-0) waa gonadotropin-sii daynta hoormoonka (GnRH) antagonist kaas oo lagu iibiyo ugu horreyn magaca calaamadda Cetrotide.Decapeptide synthetic, waxaa loo isticmaalaa taranka la caawiyay si loo joojiyo hormoonnada luteining-ka ee dhicisoobay.Daroogadu waxay u shaqeysaa iyadoo xannibaysa ficilka GnRH ee pituitary, sidaas darteed si degdeg ah u xakameynaya wax soo saarka iyo ficilka hormoonka luteining (LH) iyo hoormoonka follicle-stimulating hormone (FSH).Cetrorelix Acetate waxay ka kooban tahay noocyo kala duwan oo asiidhyada amino-dabiiciga ah ee ka hortagaya ugxan-sidaha hore ee tijaabooyinka kiliinikada, taasoo horseedaysa ururinta ugxan-sidaha iyo daaweynta tignoolajiyada taranka ee la kaalmeeyo ee bukaannada lagu hayo kicinta ugxan-sidaha.
Tilmaamaha Cetrorelix Acetate waa hormoon macmal ah oo xannibaya saameynta hormoonka sii-deynta gonadotropin (GnRH).Tignoolajiyada taranka ee la caawiyay, bukaanada leh kicinta ugxan-sidaha, waxay ka hortagaan ugxan-sidaha dhicis ah.
Falka dawooyinka Cetrorelix Acetate waa hormoonka sii daaya gonadotropin (GnRH) antagonist.GnRH waxay ku xidhmi kartaa dabaylaha xuubka unugyada pituitary.Cetrorelix acetate waxay si tartan ah ugu xidhan tahay soo-dhoweeyayaashan leh GnRH endogenous, taas oo qiyaasta-ku-tiirsanaanta joojinaysa dheecaanka hormoonka luteining (LH) iyo hoormoonka kicinta follicle (FSH) ee adenohypophysis.Saamaynta xannibaadda ayaa la soo saaray isla markiiba ka dib maamulka cetrorelix acetate, saameynta xannibaadda waxaa lagu ilaalin karaa daaweyn joogto ah.Dumarka, Cetrorelix Acetate waxay daahi kartaa heerka ugu sarreeya ee LH, taas oo dib u dhigaysa ugxanta.Haweenka ku jira kicinta ugxan-sidaha, muddada ficilku waxay ku tiirsan tahay qiyaasta.Hal dose oo ah cetrorelix 3mg ayaa lagu qiyaasay inay leedahay saameyn xannibaad ah oo ugu yaraan 4 maalmood ah, oo leh saameyn xannibaad ah oo qiyaastii 70% maalinta 4. Maamulka soo noqnoqda ee cetrorelix acetate 0.25mg saacad kasta 24 ayaa sii wadi karta saameynteeda.Saamaynta hormoon-ka-hortagga ah ee Cetrorelix Acetate ayaa si buuxda loo beddelay dhammaadka daaweynta xayawaanka iyo bini'aadamka labadaba.
Dhaqdhaqaaqa bayoolojiga Cetrorelix Acetate waa ka soo horjeedka awoodda leh ee soo-dhoweeyaha GnRH oo leh IC50 qiimaha 1.21 nM.
Bartilmaameedka IC50: 1.21 nM GnRH.
