Cisatracurium Besylate CAS 96946-42-8 Assay 95.0%~102.0% API Tayada Sare
Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Cisatracurium Besylate
CAS: 96946-42-8
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Cisatracurium Besylate |
Lambarka CAS | 96946-42-8 |
Lambarka CAT | RF-API13 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C53H72N2O12.2C6H5O3S |
Miisaanka Molecular | 1243.49 |
Meesha dhalaalaysa | 90.0 ~ 93.0 ℃ |
Xaalada Maraakiibta | Heerkulka deegaanka hoostiisa |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama ku dhawaad cad, aan ur lahayn, xoogaa Hygroscopic ah |
Solubility | Si xor ah ugu milmay dichloromethane, acetonitrile, biyo yar ku milmay |
Wareeg gaar ah | -35.0 ° ilaa -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
Aqoonsiga | Ku milmi acid hydrochoric, dropwise milo bismuth potassium iodide TS, roobab huruud ah ayaa la soo saari doonaa |
Aqoonsiga | 1. HPLC;2. IR |
Qiimayn | 95.0 ~ 102.0% (C65H82N2O18S2 ku salaysan qalalan) |
pH | 3.5 ilaa 5.0 |
Cadaynta & Midabka Xalka | Waa inuu noqdaa mid cad oo aan midab lahayn |
Khasaare xagga qalajinta | ≤2.0% |
Hadhaaga dabka | ≤0.20% |
Biraha culus | ≤20pm |
Trans-Trans Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Mono-quaternary | ≤1.50% |
Xumaanta Shaqsiga Kale | ≤1.50% |
Wadarta wasakhda | ≤5.0% |
Isomer indhaha SS-Isomer | ≤1.50% |
Isoomer indhaha RS- Isomer | ≤1.00% |
Sulfate | ≤50pm |
Ethyl | ≤0.50% |
Acetone | ≤0.50% |
Methanol | ≤0.3% |
Dichloromethane | ≤0.06% |
Acetonitrile | ≤0.041% |
Methylbenzene | ≤0.089% |
Haraaga Xalalka Acetonitrile | ≤410pm |
Heerka Imtixaanka | Farmashiyaha Shiinaha (CP) |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Cisatracurium Besylate (CAS 96946-42-8) waa nooca milixda benzene sulfonate ee atracurium.Waa nooc ka mid ah nasiyeyaasha murqaha oo aan depolarization ah oo aan dabiici ahayn oo leh door la mid ah sida tubecurarine.Qiyaasta daawaynta ma saamayso shaqada wadnaha, beerka iyo kelyaha.Sidoo kale ma laha hanti urursan.Waxa kale oo ay keeni kartaa sii deynta histamine marka loo isticmaalo qiyaaso badan.Nasashada murqaha ama xakamaynta neefsashada ee looga baahan yahay qalliinka, marka la barbar dhigo dawooyinka suuxinta ee muruqa nasinaya ee hadda kiliinikada, cisatracurium besylate laguma dheefshiido beerka ama kelyaha, waxayna leedahay xasillooni wadnaha;Saameynteeda nasashada muruqa waa 3 jeer ka xoog badan sida atracurium iyada oo aan wax saameyn ah oo dhinaca wadnaha ah.Cisatracurium besylate waxaa inta badan lagu dabaqaa suuxinta guud, waxaana si weyn loogu isticmaali karaa gelinta, daaweynta beerka iyo kelyaha oo aan shaqeynin, loo isticmaalo qalliinka wadnaha iyo xididdada dhiigga iyo bukaanka waayeelka iyo carruurta.Marka la barbar dhigo atracurium, alaabtani ma laha saameyn xun oo ku-tiirsan oo ku saabsan sii-deynta histamine;si kastaba ha ahaatee, khasaaraha ayaa ah in bukaanada qaba cillad beerka iyo kelyaha ay si taxadar leh u maamulaan.Tan iyo 1996 markii ugu horeysay ee dawadan ay soo gashay suuqa gudaha UK, wadamada shisheeye ayaa si tartiib tartiib ah u dalbaday inay beddelaan vecuronium iyo atracurium oo ah kuwa ugu muhiimsan ee nasashada murqaha.