Cyano-Irbesartan CAS 138401-24-8 daahirnimo>98.0% (HPLC) Warshada Dhexe ee Irbesartan
Qalabka Kiimikada ee Ruifu Dhexdhexaadiyaha Irbesartan:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tril Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Side Hydrochloride CAS 151257-01-1
Magaca Kiimikada | Cyano-Irbesartan |
La mid ah | CyanoIrbesartan;Irbesartan Cyano wasakhnimo;Hydrocarbon Irbesartan;Irbesartan wasakh 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl] -1,3-diazaspiro[4,4] aan-1-en-4-hal;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Lambarka CAS | 138401-24-8 |
Lambarka CAT | RF-PI1892 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C25H27N3O |
Miisaanka Molecular | 385.51 |
Cufnaanta | 1.15 |
Solubility (Ku milma) | Methanol |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa ku dhawaad cad budo ilaa Crystal |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) |
daahirnimo | >97.0% (oo ay ku jirto wadarta Nitrogen) |
Meesha dhalaalaysa | 91.0 ilaa 95.0 ℃ |
Khasaare xagga qalajinta | <1.00% |
Xumaanta Keliya | <1.00% |
Biraha culus | <20ppm |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaad / Xumaanta Irbesartan (CAS: 138402-11-6) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Cyano-Irbesartan (CAS: 138401-24-8) waa dhexdhexaad ama nijaasta Irbesartan (CAS: 138402-11-6).Irbesartan waa angiotensin II (Angiotensin II, Ang II) dib-u-qabtayaasha.Reseptors Angiotensin II waxaa loo qaybiyaa laba nooc: AT1 iyo AT2.Irbesartan waxay si xushmad leh u xannibaysaa soo-dhoweeyaha AT1 ee Angli.Waxay joojin kartaa u beddelka Ang ee Ang, waxay si gaar ah uga soo horjeedaa angiotensin-beddelka enzyme 1 reseptor (AT1).Saamaynta iska soo horjeeda ee AT1 waa 8500 jeer ka badan AT2.Waxay si xushmad leh u xannibi kartaa xiritaanka Ang iyo AT1 receptor iyada oo loo marayo Inhibit vasoconstriction iyo sii deynta aldosterone, taasoo keentay saameyn hypotensive.Alaabtani ma joojinayso angiotensin-beddelka enzyme (ACE), renin, hormoonnada kale ee soo-dhoweeya, mana joojinayso kanaalada ion ee la xidhiidha xakamaynta cadaadiska dhiigga iyo dheelitirka sodium.Irbesartan waxay sidoo kale hoos u dhigi kartaa dib-u-habaynta korantada ee myocardium, taas oo yaraynaysa heerka dhimashada bukaanka qaba hypertension.Hadda waa daawada ugu waxtarka badan ee daaweynta hypertension iyo cudurrada wadnaha iyo xididdada dhiigga.