Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) Qaybaha Dawooyinka
Ruifu Chemical waa soo saaraha hormuudka u ah Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) oo leh tayo sare.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com
Magaca Kiimikada | Hydroxypropyl-β-Cyclodextrin |
La mid ah | Cyclodextrin HPB;Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl) -beta-Cyclodextrin;beta-Hydroxypropylcyclodextrin;HBC;HPBCD;HP-β-CD |
Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
Lambarka CAS | 128446-35-5 |
Qaanuunka molecular | C63H112O42 |
Miisaanka Molecular | 1541.54 g/mol |
Meesha dhalaalaysa | 262.0 ~ 269.0 ℃ |
Cufnaanta | 1.05 |
Wareeg gaar ah [a]20/D | +120° ilaa +135° (C=1, H2O) |
Biyuhu milmayn | Ku milmay Biyaha |
COA & MSDS | La heli karo |
Tusaalaha bilaashka ah | La heli karo |
Asal ahaan | Shanghai, Shiinaha |
Summada | Kiimikada Ruifu |
Walxaha | Tilmaamaha | Natiijooyinka |
Muuqashada | Budada cad, Insipid, aan waxba galabsan | waafaqsan |
IR Spectrum | Qaybaha nuugista isku midka ah ee leh USP Hydroxypropyl Betadex RS | waafaqsan |
pH | 5.0 ~ 7.5 | 6.57 |
Cadaynta Xalka | Xalka cad oo aan midab lahayn | waafaqsan |
Khasaare xagga qalajinta | ≤10.0% | 3.5% |
Hadhaaga dabka | ≤0.20% | 0.09% |
Biraha culus | ≤20pm | <10pm |
Chloride | ≤0.05% | <0.05% |
Beddelka Molar | 0.4 ~ 1.5 | 0.63 |
Hab-dhaqanka | 10% (w/v) Xalka Biyaha ≤200μS/cm | 154µS/cm |
Darajada Beddelka | 2.8 ~ 10.5 | 5.3 |
Hadhaaga Betadex | ≤1.50% | 0.12% |
Propylene Glycol | ≤2.50% | 0.29% |
Propylene oxide | ≤1ppm | <1pm |
Wax kasta oo kale oo aan nadiif ahayn | ≤0.25% | <0.25% |
Wadarta Wasaqda Kale | ≤1.00% (marka laga reebo Betadex iyo Propylen Glycol) | 0.51% |
TAMC | ≤1000cfu/g | 30cfu/g |
TYMC | ≤100cfu/g | 10cfu/g |
Escherichia Coli | Lama ogaan karo | waafaqsan |
Salmonella | Maqan | Maqan |
Bakteeriyada Endotoxins | <10IU/g | <10IU/g |
Gabagabo | La tijaabiyay oo waafaqsan heerka USP35 |
Xidhmada:Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi bakhaar qabow, engegan oo hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.Aan ku habboonayn walxaha oksaydhaynta ee xooggan.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
Suuqyada Waaweyn?Iibiya suuqa gudaha, Waqooyiga Ameerika, Yurub, Hindiya, Kuuriya, Jabbaan, Australia, iwm.
Faa'iidooyinka?Tayada sare, qiimo jaban, adeegyo xirfadeed iyo taageero farsamo, gaarsiin degdeg ah.
TayadaHubinta?Nidaamka xakamaynta tayada adag.Qalabka xirfadlayaasha ah ee falanqaynta waxaa ka mid ah NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Imtixaanka xadka Microbial, iwm.
Tusaalooyinka?Badeecadaha intooda badani waxay bixiyaan muunado bilaash ah oo loogu talagalay qiimeynta tayada, kharashka dhoofinta waa in ay bixiyaan macaamiisha.
Hantidhawrka Warshada?Hantidhawrka warshada soo dhawoow.Fadlan horay u sii ballan.
MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
Waqtiga dirida? Haddii ay ku jirto kaydka, dammaanad bixinta saddex maalmood ah.
Gaadiidka?By Express (FedEx, DHL), hawada, badda.
Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
Isku-dhafka gaarka ah?Waxay ku siin kartaa adeegyada isku-dhafka gaarka ah si ay ugu habboonaato baahiyahaaga cilmi-baarista.
Shuruudaha Lacag-bixinta?Qaansheegga Proforma ayaa marka hore la soo diri doonaa ka dib marka la xaqiijiyo dalabka, oo lagu soo lifaaqay macluumaadka bangigayaga.Lacag bixinta T/T (Telex Transfer), PayPal, Western Union, iwm.
Sharaxaada Badbaadada | 24/25 - Iska ilaali taabashada maqaarka iyo indhaha. |
WGK Germany | 3 |
RTECS | GU2293332 |
Koodhka HS | 3505100000 |
Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) waa cyclodextrin si weyn loo isticmaalo oo wax laga beddelay, godka lipophilic oo ay sameeyeen 7 unug gulukoos.Ku milanka maandooriyaha ee biyaha ayaa si weyn loo xoojiyey iyadoo lagu kaafiyey HP-β-CD.Dahaarka gudaha, qaabaynta sii daynta joogtada ah, gaarsiinta daroogada buccal iyo transdermal.
Hydroxypropyl-β-Cyclodextrin, derivative hydroxyalkyl, helay codsiga sida baabuur qaabaynta in loo isticmaalo si kor loogu qaado milanka daawooyinka ee xal aqueous ah gaarsiinta guul ee wakiilada caafimaadka hababka noolaha.Guud ahaan waxaa loo shaqeeyaa beddelka α-, β- iyo γ-Cyclodextrins.
Hydroxypropyl betadex si weyn baa loogu baadhay farmashiyaha waxaana asal ahaan loo isticmaalay sidii solubilizer molecules hydrophobic ee dareeraha afka, adka afka, parenterals, daawada neefta mitir ee cadaadiska ah, daawada neefta budada qalalan, iyo qaabaynta jirka.Waxa kale oo la tusay inay u dhaqanto sidii xasiliye inta lagu jiro habaynta iyo kaydinta hababka.Dhismayaasha ka mid noqoshada Hydroxypropyl betadex ayaa la sheegay inay muujinayaan sifooyin farsamo oo ka duwan alaabta saafiga ah.Faa'iidada la soo sheegay ee hydroxypropyl betadex ee b-cyclodextrin aan la beddelin ayaa ah milmaheeda biyaha weyn.
1. Solubilization iyo solubilization, samee daawooyinka aan milmi karin, hagaajinta milanka qaybaha firfircoon ee daawooyinka saliidda leh, bartilmaameedka daroogada iyo ilaalinta waxtarka maaddooyinka daroogada.
2. Hagaajinta bioavailability daawadu, kordhiso saamaynta daawaynta ee daawada ama la yareeyo qiyaasta.
3. Hagaajin ama xakamee heerka sii daynta daawada si loo yareeyo waxyeelada.
4. Dabool urta xun.
1) Dhinaca dawada.
1. Hydroxypropyl Beta Cyclodextrin waxay kordhin kartaa milanka daawada iyo helitaanka noolaha, sidoo kale waxay kordhisaa saamaynta wanaagsan waxayna yaraynaysaa qiyaasta.
2. HP-β-CD wuxuu xakameyn karaa ama hagaajin karaa xawaaraha falcelinta, hoos u dhigi karaa sunta daroogada wuxuuna wanaajin karaa xasilloonida daroogada.
3. Solubilizer irbad ku habboon iyo walxaha daroogada sababtoo ah dhaqdhaqaaqa hoose ee dusha sare iyo dhaqdhaqaaqa hemolytic, ma laha xanaaq muruqa.
4. HP-β-CD kaliya looma isticmaalo dawooyinka afka laga qaato, duritaanka, nidaamka gudbinta daroogada xuubka, habka gudbinta daroogada transdermal, lipotropy bartilmaameedka daroogada sidaha, laakiin sidoo kale waxaa loo isticmaali karaa sida wakiilka difaaca borotiinka iyo stabilizer.
5. Si loo hagaajiyo sifooyinka organoleptic ee firfircoonida qadhaadh ama aan fiicnayn.
2) Goobta cuntada.
1. HP-β-CD waxay ka hortagi kartaa uumiga walxaha kacsan ilaalinta xasiloonida nafaqooyinka, ka takhalusto urta xun waxayna si weyn u wanaajin kartaa saameynta emulsification iyadoo la isku daro isticmaalka emulsifiers cuntada.
2. HP-β-CD waxa kale oo ay ka dhigi kartaa ilaalinta cuntada si tartiib tartiib ah, kor u qaadda saamaynta daxalka iyo kordhinta nolosha shelf ee cuntada.
3) Warshadaha Isqurxinta
1. Qurxinta alaabta ceeriin ee loo isticmaalo xasilinta, emulsifier, solubilizer iwm.
2. HP-β-CD waxay yarayn kartaa kicinta maqaarka, waxayna kor u qaadi kartaa xasilloonida qaybaha waxtarka leh
3. HP-β-CD waxay yarayn kartaa ama qarin kartaa ur xun ee unugyada nafaqada.
4. Kahortagga isku-dhafka nafaqeynta ee kacsan, oksaydheynta, kordhinta awood la'aanta, nuxurka, udgoonka biyaha-milmi kara oo udgoonka sii daaya oo waara.