DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay>98.0% (HPLC) Warshada
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee DAPT (GSI-IX) (CAS: 208255-80-5) oo leh tayo sare leh, γ-Secretase Inhibitor.Kiimikada Ruifu waxay keentaa asiidhyo amino oo taxane ah iyo soosaarayaal.Waxaan bixin karnaa gaarsiinta adduunka oo dhan, tiro yar iyo tiro badan oo la heli karo.Iibso DAPT,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | DAPT |
| La mid ah | GSI-IX;γ-Secretase Inhibitor IX;gamma-Secretase Inhibitor;LY-374973;(3,5-Difluorophenylacetyl)-Ala-Phg-OtBu;(3,5-Difluorophenylacetyl)-L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N-[N-(3,5-Difluorophenacetyl)-L-Alanyl]-S-Phenylglycine t-Butyl Ester;(2S)-N-[2-(3,5-Difluorophenyl)acetyl]-L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Heerka Saamiyada | In Stock |
| Lambarka CAS | 208255-80-5 |
| Qaanuunka molecular | C23H26F2N2O4 |
| Miisaanka Molecular | 432.47 |
| Cufnaanta | 1.213 g/cm3 |
| Meesha dhalaalaysa | 142.0 ~ 146.0 ℃ |
| Xasaasi ah | Xasaasida kulaylka |
| Solubility | Ku milmay DMSO |
| Heerkulka Kaydinta | Ku kaydi 2-8℃ |
| COA & MSDS | La heli karo |
| Summada | Kiimikada Ruifu |
| Bayaanada Badbaadada | 24/25 - Iska ilaali taabashada maqaarka iyo indhaha. | ||
| WGK Germany | 3 | Koodhka HS | 2922491990 |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Caddaan ama Banaan-cad budada Crystalline | waafaqsan |
| Khasaare xagga qalajinta | <0.40% | 0.21% |
| Hadhaaga dabka | <0.40% | 0.20% |
| Biraha culus (sida Pb) | ≤20pm | <20ppm |
| Habka Qiimaynta / Falanqaynta | >98.0% (HPLC) | 98.62% |
| Kaarboon by Falanqaynta Elemental | 62.1 ~ 64.1% | waafaqsan |
| Nitrojiin by Falanqaynta Elemental | 6.20 ~ 6.70% | waafaqsan |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | waafaqsan |
| NMR Spectrum | Waafaqsan Qaab-dhismeedka | waafaqsan |
| Gabagabo | Alaabtan iyadoo la raacayo Heshiisyada Kormeerka ee Heerarka Ganacsiga | |
| Nolosha shelf | 24 bilood laga bilaabo taariikhda wax soo saarka haddii si sax ah loo kaydiyo | |
Xidhmada: Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha daboolan meel qabow, engegan (ku kaydi 2-8℃) iyo bakhaar hawo leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
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Faa'iidooyinka?Tayada sare, qiimo jaban, adeegyo xirfadeed iyo taageero farsamo, gaarsiin degdeg ah.
TayadaHubinta?Nidaamka xakamaynta tayada adag.Qalabka xirfadlayaasha ah ee falanqaynta waxaa ka mid ah NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Imtixaanka xadka Microbial, iwm.
Tusaalooyinka?Badeecadaha intooda badani waxay bixiyaan muunado bilaash ah oo loogu talagalay qiimeynta tayada, kharashka dhoofinta waa in ay bixiyaan macaamiisha.
Hantidhawrka Warshada?Hantidhawrka warshada soo dhawoow.Fadlan horay u sii ballan.
MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
Waqtiga dirida? Haddii ay ku jirto kaydka, dammaanad bixinta saddex maalmood ah.
Gaadiidka?By Express (FedEx, DHL), hawada, badda.
Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
Isku-dhafka gaarka ah?Waxay ku siin kartaa adeegyada isku-dhafka gaarka ah si ay ugu habboonaato baahiyahaaga cilmi-baarista.
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DAPT (GSI-IX) (CAS: 208255-80-5), awood iyo horjooge gaar ah ee γ-sirta.DAPT waa xannibaadaha γ-secretase (IC50 ee neerfayaasha asaasiga ah ee aadanaha = 115 nM wadarta Aβ ama 200 nM ee Aβ42 gaar ahaan).Maamulka afka ee DAPT ayaa la muujiyay inuu hoos u dhigo heerarka Aβ ee laga soosaaray maskaxda, dareeraha cerebrospinal iyo balaasmaha jiirka iyo jiirka.DAPT waxay xannibtaa calaamadaynta Notch taasoo kor u qaadaysa kala soocida neerfayaasha unugyada hore.Waxay kordhisaa unugyada iPS oo aan lahayn oncogenes KLF4 iyo CMYC5.Unuggu dalan karoDAPT waxaa loo isticmaalaa daraasadda samaynta β-amyloid.DAPT ayaa la muujiyay in ay joojiso calaamadaha Notch ee daraasadaha ku saabsan cudurrada difaaca jirka iyo lymphoproliferative, sida ALPS iyo lupus erythematosus, iyo sidoo kale korriinka unugyada kansarka, angiogenesis, iyo kala soocida unugyada taranka ee bini'aadamka.Waxay joojisaa calaamadaynta 'Notch in vitro'.Waxay joojisaa wadarta guud ee wax soo saarka Aβ iyo Aβ42 ee dhaqamada asaasiga ah ee aadanaha (qiyamka IC50 waa 115 iyo 200 nM, siday u kala horreeyaan) iyada oo aan wax saameyn ah ku yeelan heerarka APPα iyo APPβ.Dhiiga-maskaxda oo xannibaad ahQaybta kobaca 3D iyo qayb ka mid ah warbaahinta kala-duwanaanshaha organoid maskaxda.
