Daptomycin CAS 103060-53-3 Nadiifnimada ≥95.0% API Sawirka Nadiifinta Sare

Daptomycin CAS 103060-53-3 Nadiifinta ≥95.0% API Nadaafadda Sare

Sharaxaad Gaaban:

Magaca Kiimikada: Daptomycin

CAS: 103060-53-3

Muuqashada: Budada Jaallaha ah ee Jaallaha ah ama Baalka ah

Daahirsanaanta: ≥95.0% (waxaa lagu xisaabiyaa iyadoo lagu saleynayo qallalan)

Daptomycin ee daaweynta cudurrada maqaarka iyo unugyada jilicsan qaarkood oo ay keento bakteeriyada garaam-positive.

API Tayada Sare, Wax soo saarka Ganacsiga

Inquiry: alvin@ruifuchem.com

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Sharaxaad:

Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Daptomycin
CAS: 103060-53-3
API Tayada Sare, Wax soo saarka Ganacsiga

Guryaha Kiimikada:

Magaca Kiimikada	Daptomycin
La mid ah	LY146032
Lambarka CAS	103060-53-3
Lambarka CAT	RF-API10
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C72H101N17O26
Miisaanka Molecular	1620.69
Meesha dhalaalaysa	202.0 ~ 204.0 ℃
Solubility	Solube ee methanol
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Jaallaha ah ee Jaallaha ah ama Bacaadka ah
Aqoonsiga HPLC	Waqtiga haynta ee ugu sarreysa xalka muunada waa inuu u dhigmaa heerka tixraaca.
Aqoonsiga IR	spectrum IR ee muunada imtixaanku waa inay la socotaa spectrum IR ee heerka tixraaca.
Muuqashada Xalka	Caddayn Xalku waa inuu noqdaa mid cad ama yuusan kasii dhawaaqin ka joojinta tixraaca II.
Wareegga indhaha ee gaarka ah	+17.0° ilaa +25.0°
pH	4.0 ilaa 5.0
Hadhaaga dabka	≤1.0%
Anhydro-Daptomycin	≤2.5%
β-Isomer	≤0.50%
Biyo la'aanta	≤0.50%
Xumaanta 1	≤0.75%
Impurtiy 2	≤0.75%
Impurtiy 3	≤0.75%
Wax kasta oo wasakh kale ah	≤0.15%
Wadarta wasakhda	≤5.0%
Biraha culus	≤30pm
Biyo	≤5.0%
daahirnimo	≥95.0% (waxaa lagu xisaabiyaa qaab qallalan)
Bakteeriyada Endotoxins	<0.3EU/mg
Haraaga Xalalka n-Butanol	≤5000ppm
Hadhaaga xalalka isopropanol	≤5000ppm
Haraaga Xalalka Ethanol	≤5000ppm
Xadka Microbial TAMC	≤100cfu/g
Xadka Microbial TYMC	≤10cfu/g
E.Coil	Lama ogaan
Heerka Imtixaanka	Heerka Ganacsiga
Xaaladaha Kaydinta	Ku kaydi weelal cidhiidhi ah, kuna kaydi -25 ~ -10℃.
Isticmaalka	Walaxda Farmashiyeedka Firfircoon (API)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

FAQ:

Codsiga:

Daptomycin (CAS: 103060-53-3) waa nooc ka mid ah antibiyootiga lipoppeptide meerto ah oo leh qaab dhismeed cusub.Waxaa laga soosaaraa maraq halsano Streptomyces.Waxaa helay Shirkadda Eli Lilly 1980-meeyadii, waxaana si guul leh u soo saartay 1997-kii Cubist Pharmaceuticals.Ma aha oo kaliya in ay leedahay qaab-dhismeedka kiimikada cusub, laakiin sidoo kale waxay leedahay qaab ficil ah oo ka duwan antibiyootig kasta oo hore loo ansixiyay: waxay joojisaa unugyada iyada oo carqaladeynaysa gaadiidka asiidhyada amino-ka iyada oo loo marayo xuubka unugyada, taas oo xannibaysa derbiga unugyada peptidoglycan biosynthesis iyo beddelidda dabeecadda xuubabka unugga.Waxay burburin kartaa shaqada xuubabka unugga bakteeriyada dhinacyo badan, waxayna si degdeg ah u dishaa bakteeriyada garaam-positive.Marka laga soo tago doorka saamaynta ay ku yeelanayso inta badan bakteeriyada garaam-positive ah ee kiliinikada ah, waxaa ka sii muhiimsan, Daptomycin waxay leedahay waxtar xoog leh oo lagu daweynayo noocyada go'doonsan kuwaas oo muujiyay calaamadaha caabbinta methicillin, vancomycin iyo linezolid.Hantidaani waxay muhiimad caafimaad u leedahay bukaanada qaba caabuq daran.Bishii Sebtembar 2003, Maamulka Cuntada iyo Dawooyinka ee Mareykanka ayaa oggolaaday markii ugu horreysay in Daptomycin (CAS: 103060-53-3) loo codsado daawaynta cudurrada maqaarka ee daran.Bishii Maarso 2006, waxaa loo oggolaaday daaweynta cudurrada faafa.Bishii Janaayo 2006, waxaa ansixiyay Guddiga Yurub daaweynta cudurrada maqaarka iyo unugyada jilicsan qaarkood oo ay keento bakteeriyada garaam-positive ah.Sebtembar 6, 2007, Cubist Pharmaceuticals ayaa ku dhawaaqday in Midowga Yurub uu ansixiyay dawadiisa bakteeriyada, Cubicin ee daaweynta wadnaha saxda ah ee endocarditis ee uu keeno caabuqyada Staphylococcus aureus iyo cudurrada maqaarka iyo jilicsanaanta jilicsan ee la xiriira cudurrada ay keento Staphylococcus aureus.