Darifenacin Hydrobromide Darifenacin HBr CAS 133099-07-7 Assay ≥99.0% API Tayada Sare
Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca Kiimikada: Darifenacin Hydrobromide
CAS: 133099-07-7
Darifenacin hydrobromide waa M3 muscarinic reseptor antagonist oo la doortay oo loo isticmaalo daawaynta kaadi-la'aanta kaadida iyo xanuunka kaadiheysta firfircoonida.
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Darifenacin Hydrobromide |
La mid ah | Darifenacin HBr;UK-88525;Enablex |
Lambarka CAS | 133099-07-7 |
Lambarka CAT | RF-API94 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C28H30N2O2.HBr |
Miisaanka Molecular | 507.46 |
Meesha dhalaalaysa | 228.0 ~ 230.0 ℃ |
Solubility | DMSO: 20mg/ml milmaya, cad |
Heerkulka Kaydinta | Ku kaydi wakhtiga dheer at -20 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Crystalline White |
Solubility | Si yar ugu milmi kara Methanol, In yar Biyaha ku milmi kara |
Aqoonsiga IR | Spectrum muunadu waxay u dhigantaa heerka tixraaca |
Aqoonsiga HPLC | Waqtiga haynta ee ugu sarreeya ee xalka muunadda ayaa u dhigma kan xalka caadiga ah |
Walxaha laxidhiidha | |
Max.Xumaanta Keliya | ≤0.50% |
Wadarta wasakhda | ≤1.0% |
Isomer indhaha | ≤0.50% |
Xalalka Haraaga ah | |
Ethyl acetate | ≤0.50% |
Ethanol | ≤0.50% |
Methanol | ≤0.30% |
Acetone | ≤0.50% |
1-Butaanool | ≤0.50% |
Khasaare xagga qalajinta | ≤1.0% (ku qallaji 105 ℃ hawo koronto ku qalajisa ilaa miisaan joogto ah) |
Hadhaaga dabka | ≤0.10% |
Biraha culus | ≤20pm |
Qiimayn | ≥99.0% (oo ku salaysan qalalan) |
Nolosha shelf | 24 bilood |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API, Kaadi-haysta Firfircoon |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Darifenacin Hydrobromide, Darifenacin HBr (CAS 133099-07-7), af ahaan firfircoon, hal mar maalintii xulashada M3 antagonist, ayaa loo bilaabay daawaynta kaadiheysta firfircoonida ee bukaanka leh calaamadaha rabitaanka kaadida kaadida, degdega iyo inta jeer.Daroogadu waxay si xushmad leh u joojisaa soo-dhoweynta M3 ee muruqa detrusorka iyadoo la ilaalinayo soo-dhoweynta M1 iyo M2 kuwaas oo la rumeysan yahay inay ku lug leeyihiin habka dhexe ee neerfayaasha iyo shaqada wadnaha iyo xididdada siday u kala horreeyaan.Xarunta waxaa markii hore soo saartay Pfizer waxaana shati loo siiyay Novartis iyo Bayer.