Despropionyl Ramelteon Hydrochloride CAS 196597-80-5 daahirnimo>98.0% (HPLC)

Sharaxaad Gaaban:

Magaca Kiimikada: (S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)etylamine Hydrochloride

La mid ah: Despropionyl Ramelteon Hydrochloride

CAS: 196597-80-5

Daahirsanaanta:>98.0% (HPLC)

Muuqashada: Budada Adag ee Cadaan ilaa Cadaan

Dhexdhexaadka Ramelteon (CAS: 196597-26-9)

Xiriirka: Dr. Alvin Huang

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Sharaxaad:

Soo saaraha iyo alaab-qeybiyaha hormuudka ka ah
Dhexdhexaadiyaha Ramelteon:
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Guryaha Kiimikada:

Magaca Kiimikada	(S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)etylamine Hydrochloride
La mid ah	Despropionyl Ramelteon Hydrochloride;(S)-2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl)ethanamine Hydrochloride;(S)-2- (2,6,7,8-Tetrahydro-1H-Indeno [5,4-b]furan-8-yl) etanamine HCl;Ramelteon wasakh 15 HCl;Ramelteon Amine wasakh
Lambarka CAS	196597-80-5
Lambarka CAT	RF2888
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C13H17NO.HCl
Miisaanka Molecular	239.74
Meesha dhalaalaysa	270 ℃
Ku milmay biyaha	Ku milmay Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Adag ee Cadaan ilaa Cadaan
Daahirnimada / Habka Falanqaynta	>98.0% (HPLC)
Khasaare xagga qalajinta	<1.00%
Xumaanta Keliya	<1.00%
Wadarta wasakhda	<2.00%
1 H NMR Spectrum	Waafaqsan Qaab-dhismeedka
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadka Ramelteon (CAS: 196597-26-9)

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Codsiga:

(S)-2-(1,6,7,8-Tetrahydro-2H-Indeno [5,4-b]furan-8-yl)etylamine Hydrochloride, sidoo kale loo yaqaan Despropionyl Ramelteon Hydrochloride (CAS: 196597-80-5). ) waa dhexe ee Ramelteon (CAS: 196597-26-9).Ramelteon (TAK-375) waa melatonin receptor agonist oo loogu talagalay dadka MT1 iyo MT2 reseptors iyo qaboojiyeyaasha hore ee maskaxda melatonin ee leh Ki of 14 pM, 112 pM iyo 23.1 pM, siday u kala horreeyaan.Unugyada melatonin waxa la beddelay inta badan iyadoo lagu beddelay nitrogen-ka giraanta indole-ka oo lagu beddelay kaarboon si loo siiyo giraanta indane iyo iyada oo lagu daray kooxda 5-methoxyl ee giraanta indole-ka oo lagu beddelo giraan furan oo adag.Xulashada Ramelteon ee ka soo baxday ee MT1 reseptor ayaa siddeed jeer ka badan kan MT2 reseptor.Si ka duwan melatonin, waxay wax ku ool u tahay bilaabista hurdada (firfircoonida MT1) halkii ay dib u hagaajin lahayd laxanka wareegga (MT2).Waxay u muuqataa inay si gaar ah uga waxtar badan tahay melatonin laakiin aan waxtar lahayn marka loo eego benzodiazepines sida hypnotic.Muhiimad ahaan, dawadani ma laha wax masuuliyad ah oo la qabatimay (ma aha walaxda la xakameeyey).Natiijo ahaan, dhawaan ayaa loo oggolaaday daaweynta hurdo la'aanta.