Diethylphosphonoacetic Acid CAS 3095-95-2 daahirnimo>99.5% (HPLC) Afatinib Dimaleate Warshada Dhexe

Sharaxaad Gaaban:

Magaca Kiimikada: Diethylphosphonoacetic Acid

CAS: 3095-95-2

Daahirsanaanta:>99.5% (HPLC)

Muuqaalka: Dareere aan Midab lahayn

Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

Tayada Sare, Wax Soo Saarka Ganacsiga

E-Mail: alvin@ruifuchem.com


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Sharaxaad:

Guryaha Kiimikada:

Magaca Kiimikada Diethylphosphonoacetic acid
La mid ah 2- (Diethoxyphosphosphoryl) acetic acid;(Diethoxyphosfinyl) acetic acid;Diethyl Carboxymethylphosphonate;NSC 272281
Lambarka CAS 3095-95-2
Lambarka CAT RF-PI2024
Heerka Saamiyada Kaydka dhexdiisa, Awoodda Wax-soo-saarka 30MT/Bishii
Qaanuunka molecular (C2H5O)2P(O)CH2CO2H
Miisaanka Molecular 196.14
Barta Karsan 150 ℃/0.05 mmHg ( shidan)
Cufnaanta 1.220 g/ml at 25℃ ( shid)
Tusmada Dib-u-celinta n20/D 1.445 (lit.)
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Dareere aan Midab lahayn
Aqoonsiga (HPLC) Waqtiga haynta ee ugu sarraysa ee laga helay muunadda waxay ku dhex jirtaa 5% muunadda tixraaca.
Daahirnimada / Habka Falanqaynta > 99.5% (HPLC)
Infrared Spectrum Waafaqsan Qaab-dhismeedka
Proton NMR Spectrum Waafaqsan Qaab-dhismeedka
Qoyaanka (KF) <0.50%
Wadarta wasakhda <0.50%
Heerka Imtixaanka Heerka Ganacsiga
Isticmaalka Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

Xidhmada & Kaydinta:

Xidhmada: Dhalada fluorinated, 25kg/ Durbaan, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

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FAQ:

Codsiga:

Diethylphosphonoacetic Acid (CAS: 3095-95-2), Falimaha sida nucleophile ee falcelinta dheeriga ah ee nucleophilic ee isku dhafka epoxides-ka allene Reactant for: Stereoselectivity Studies ee falcelinta Staudinger;Samaynta Enantioselective ee diols iyada oo loo marayo epioxidation iyo falcelinta fuuq-celinta;Falcelinta Horner-Wadsworth-Emmons;Chelation-ka fog ayaa la xakameeyey Ireland-Claisen dib u habeyn;Dareen-celinta Ugi-Dieckmann ee isku-dhafka walxaha tetramic acid;Loo isticmaalo in lagu sameeyo dhex-dhexaadinta fosphonoester-ka ee falcelinta HEW intramolecular.Diethylphosphonoacetic Acid waa dhexdhexaad Afatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate waxa u ansixisay Maamulka Cuntada iyo Dawooyinka ee Maraykanka (FDA) 2013 si loogu daweeyo kansarka sambabada unugyada aan yarayn (NSCLC).Gaar ahaan, waxaa loo oggolaaday bukaanada soo bandhigaya burooyinka NSCLC ee metastatic kuwaas oo ay ku jiraan xuubka koritaanka epidermal (EGFR) exon deletions ama exon 21 mutations.Afatinib Dimaleate waa horjooge isku xidhan oo ah ErbB tyrosine kinases (tyk), kaas oo hoos u dhigaya calaamadaynta ErbB iyada oo la isku xidhayo aan laga noqon karin ee goobaha xidhitaanka EGFR tyk.

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