Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory Nadaafad Sare
Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Doxorubicin Hydrochloride
CAS: 25316-40-9
Wakiilka Antibiyootiga Antitumor.Waxay joojisaa DNA Topoisomerase II
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Doxorubicin Hydrochloride |
La mid ah | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
Lambarka CAS | 25316-40-9 |
Lambarka CAT | RF-API38 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C27H30ClNO11 |
Miisaanka Molecular | 579.98 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Orange-Cas ama Budada Crystalline Cas;Ma jiro caddayn muuqata oo ku saabsan wasakhaynta walxaha shisheeye |
Solubility | Ku milmay biyaha iyo methanol;wax yar oo ku milma ethanol;ficil ahaan aan lagu milmi karin acetone |
Aqoonsiga A | Baaxadda IR waxay u dhigantaa spectrum IR ee heerka tixraaca |
Aqoonsiga B | Waqtiga haynta ee ugu sarreysa doxorubicin ee chromatogram-ka diyaarinta Assay waxay u dhigantaa tan ku jirta chromatogram-ka diyaarinta Heerka, sida laga helay Assay. |
pH | 4.0 ~ 5.5 |
Waxyaabaha Biyaha | ≤4.0% |
Walxaha laxidhiidha | |
wasakh A (Doxorubicinol) | ≤0.50% |
Wax kasta oo kale oo aan la aqoon | ≤0.20% |
Wadarta wasakhda aan la garanayn | ≤0.50% |
Wadarta wasakhda | ≤1.0% |
Qiimayn | 98.0% ~ 102.0% ee C27H30ClNO11 waxaa lagu xisaabiyaa ku salaysan anhydrous, dareere-free |
Xalalka Haraaga ah | |
Acetone | ≤0.50% |
Acetone + ethanol | ≤2.5% |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Heerka Imtixaanka | Heerka Tixraaca Pharmacopeia ee Maraykanka (USP). |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee Doxorubicin Hydrochloride (CAS: 25316-40-9) oo leh tayo sare leh.Doxorubicin hydrochloride, antibiyootiga anthracycline cytotoxic, waa wakiilka kiimoterabiga ka hortagga kansarka.Doxorubicin hydrochloride waa DNA bini aadamka topoisomerase I iyo topoisomerase II inhibitor leh IC50s ee 0.8 μM iyo 2.67 μM, siday u kala horreeyaan.Doxorubicin hydrochloride waxay keentaa apoptosis iyo autophagy.Doxorubicin waa wakiilka antitumor ee awood leh oo ka hortagaya noocyo badan oo malignancies ah, oo ay ku jiraan leukemias, sarcomas, kansarka naasaha, kansarka sambabada unugyada yaryar iyo kansarka ugxansidaha.