Entecavir Monohydrate CAS 209216-23-9 API Warshada Tayada Sare ee Kahortagga Fayraska Cagaarshowga B Caabuqa
Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca Kiimikada: Entecavir Monohydrate
CAS: 209216-23-9
Loo isticmaalo daawaynta Caabuqa Cagaarshowga B
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Entecavir monohydrate |
La mid ah | Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl] guanine Monohydrate |
Lambarka CAS | 209216-23-9 |
Lambarka CAT | RF-API79 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C12H17N5O4 |
Miisaanka Molecular | 295.3 |
Meesha dhalaalaysa | >220℃ |
Cufnaanta | 1.81 |
Xaalada Maraakiibta | Lagu soo raray Heer kulka jawiga |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ama ku dhawaad cad budada crystalline |
Solubility | Si Xor Ah Ugu Milmay Dimethylformamide, In Yar Biyo, Ethanol iyo Methanol |
Aqoonsiga IR | Spectrum muunadu waxay u dhigantaa heerka tixraaca |
Aqoonsiga HPLC | Waqtiga haynta ee muunadda imtixaanku waxay u dhigantaa heerka tixraaca |
Waxyaalaha biyaha (waxaa qoray KF) | 5.5% ~ 6.5% |
Wareegga indhaha ee gaarka ah | +24.0° ilaa +30.0° (DMF: MeOH=1:1 C=1%) (walax anhydrous ah) |
Hadhaaga dabka | ≤0.10% |
Walxaha laxidhiidha | |
Furontecavir | ≤0.10% |
Entecavir 1-Epimer | ≤0.10% |
Entecavir 3-Epimer | ≤0.10% |
8-Methyoxy Entecavir | ≤0.10% |
Entecavir 4-Epimer | ≤0.10% |
8-Hydroxy Entecavir | ≤0.10% |
4-Dimethylsilyl Entecavir | ≤0.10% |
Isku dhafka Entecavir A | ≤0.10% |
Najaasad kasta oo aan la cayimin | ≤0.10% |
Wadarta wasakhda | ≤0.30% |
Xalalka Haraaga ah | |
Methanol | ≤600pm |
Dichloromethane | ≤300pm |
Ethyl acetate | ≤1000ppm |
Tetrahydrofuran | ≤720pm |
Toluene | ≤890pm |
Benzyl Chloride | ≤1000ppm |
Khamriga Benzyl | ≤1000ppm |
Xadka Microbial | |
Wadarta Tirooyinka Aerobic | ≤100cfu/g |
Khamiir iyo caaryaal | ≤10cfu/g |
Escherichia Coli | Waa in aan la ogaan |
Biraha culus | ≤10pm |
Qiimayn | 98.0% ~ 102.0% (HPLC; ku salaysan anhydrous) |
Cabbirka Qaybaha | 95% qaybuhu waa inay ahaadaan 125um gudahood |
Heerka Imtixaanka | Heerka Ganacsiga;USPharmacopoeia (USP) Heerka |
Isticmaalka | Daawooyinka fayraska ee loo isticmaalo daawaynta Caabuqa Cagaarshowga B |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
![1](https://www.ruifuchemical.com/uploads/15.jpg)
![](https://www.ruifuchemical.com/uploads/23.jpg)
Entecavir Monohydrate (CAS 209216-23-9) waa daawada afka laga qaato ee ka hortagga fayraska ee loo isticmaalo daawaynta caabuqa Cagaarshowga B (HBV).Entecavir Monohydrate waa analog nucleoside ah (si gaar ah, analoogga guanine) kaas oo joojiya qorista dib u dhigista, nuqulka DNA-ga iyo qorista fayraska.Waa nooc cusub oo ah cyclopentyl acyl guanosine ka-hortagga fayraska fayraska cagaarshowga B oo leh saameynteeda farmashiyeed sida Entecavir.Waxa lagu daaweeyaa Cagaarshowga B ee dadka qaangaarka ah, kaas oo ay ku jiraan taranka fayraska ee firfircoon, kordhinta serum transaminase ALT ama nabarrada firfircoon ee laga helay beerka histology.Entecavir Monohydrate waa horjooge awood leh oo doorta HBV, oo leh EC50 ee 3.75 nM ee unugga HepG2.Entecavir waa dib-u-dejiyaha transcriptase.Waxay ka hortagtaa Fayraska Cagaarshowga B (HBV) inuu tarmo waxayna yareysaa tirada fayraska ee jirka.
-
Entecavir Monohydrate CAS 209216-23-9 API Xaqiiqda...
-
Entecavir CAS 142217-69-4 Tayada Sare ee Warshada API
-
Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiv...
-
Acyclovir CAS 59277-89-3 API Factory Antiviral ...
-
Tiopronin CAS 1953-02-2 Tayada Sare ee Warshada API...
-
Sorafenib Tosylate CAS 475207-59-1 daahirnimo ≥99.0...
-
Eflornithine Hydrochloride Monohydrate CAS 9602...
-
Darunavir Ethanolate CAS 635728-49-3 daahirnimo ≥99...
-
Darifenacin Hydrobromide Darifenacin HBr CAS 13...
-
Dantrolene Sodium Salt Hydrate CAS 14663-23-1 A...
-
Daptomycin CAS 103060-53-3 Purity ≥95.0% API Fa...
-
Citicoline Sodium Salt Hydrate CAS 33818-15-4 A...
-
Cefotaxime Sodium Salt CAS 64485-93-4 Assay ≥91...
-
Cholestyramine CAS 11041-12-6 USP API Warshada H...
-
Cinchonidine CAS 485-71-2 Assay 98.5% ~ 101.0% AP...