Erlotinib Hydrochloride CAS 183319-69-9 daahirnimo>99.0% (HPLC)

Sharaxaad Gaaban:

Magaca Kiimikada: Erlotinib Hydrochloride

La mid ah: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Daahirnimada (HPLC): >99.0%

Muuqashada: Caddaan ilaa-cad-cad budada crystalline

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Sharaxaad:

Soo saaraha hormuudka ah iyo alaab-qeybiyaha Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-hal CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Guryaha Kiimikada:

Magaca Kiimikada	Erlotinib Hydrochloride
La mid ah	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis (2-methoxyethoxy) -4- (3-ethynylanilino) quinazoline Hydrochloride;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amin HCl
Lambarka CAS	183319-69-9
Lambarka CAT	RF-PI2242
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C22H24ClN3O4
Miisaanka Molecular	429.90
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Crystalline ee Caddaan iyo Off-White
Aqoonsiga	A: IR: Ka-hortagga Tixraaca Tixraaca B: HPLC: Ka jawaabaya Tixraaca RT
Solubility	In yar oo Biyaha ku milmi kara, Waxoogaa ku milmi kara Methanol oo si ficil ah ugu milmi karin Acetonitrile, Acetone, Ethyl Acetate iyo Hexane
Meesha dhalaalaysa	223.0 ~ 229.0 ℃
Khasaare xagga qalajinta	<0.50%
Hadhaaga dabka	<0.20%
Biraha culus	<20ppm
Xumaanta Keliya	<0.50%
Wadarta wasakhda	<1.00%
Xalalka Haraaga ah
Pyridine	<4000pm
Chloroform	<4000pm
DMF	<3000pm
Daahirnimada / Habka Falanqaynta	>99.0%
Habka Qiimaynta / Falanqaynta	98.5% ~ 101.0% (Waxa lagu xisaabiyaa ku salaysan Anhydrous)
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	API

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka:

FAQ:

Codsiga:

Erlotinib Hydrochloride (CAS: 183319-69-9) waa molecule yar oo ka mid ah xuubka koritaanka epidermal tyrosine kinase reversible inhibitor, waxaa inta badan loo isticmaalaa daaweynta kansarka sanbabada unugyada yaryar ee gudaha ama metastatic. kansarka ganaca.Erlotinib Hydrochloride waxaa la ansixiyay bishii Noofambar, 2004, si loogu daweeyo kansarka sanbabada ee aan unugga yareyn ee sare ama metastatic.Waxay ka tirsan tahay isla fasalka Gefitinib, quinazoline kale oo loo oggolaaday daaweynta kansarka sambabada sare, laakiin leh guryaha farmashiyaha oo la hagaajiyay.Unugyada waxaa asal ahaan ka soo jeeda Pfizer waxaana la bilaabay iyadoo lala kaashanayo OSI, taasoo qaadatay xuquuq buuxda oo dawada markii Pfizer ay ku biirtay Warner Lambert.Intaa ka dib, Genentech/Roche waxay heshiis shatiga la gashay OSI si ay u horumariso oo ay ugu suuq gayso dawada Maraykanka iyo Adduunka oo dhan.Xakamaynta kobaca epidermal ee xulashada (EGFR) -tyrosine kinase inhibitor.Antineoplastic.Erlotinib Hydrochloride waa HER1/EGFR inhibitor leh IC50 ee 2 nM.Erlotinib HCl waxaa loo heli karaa sida 25-, 100-, iyo 150-mg kiniin ah maamulka afka.