Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate
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Magaca Kiimikada | Ethyl (S)-4-Chloro-3-hydroxybutyrate |
La mid ah | (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester |
Lambarka CAS | 86728-85-0 |
Lambarka CAT | RF-PI139 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C6H11ClO3 |
Miisaanka Molecular | 166.6 |
Cufnaanta | 1.19 g/ml at 25℃ ( shid) |
Tusmada Dib-u-celinta | n20/D 1.453 (lit.) |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Dareere Jaalle ah oo aan Midab lahayn |
Daahirnimada / Habka Falanqaynta | ≥98.0% (GC) |
Qoyaanka (KF) | ≤0.50% |
Ethyl-4-Chloro Aceto Acetate | ≤0.50% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Dawada;Isku-dhafka dabiiciga ah |
Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Habka falanqaynta
Sharaxaada
Qaado qiyaastii 10ml saxan quraarad nadiif ah oo qalalan oo hubi.
Wareegid gaar ah
Si sax ah ugu wareeji qiyaastii 1.0g oo muunad ah kuna wareeji 100ml caag mug leh oo lagu milmay10 ml oo chloroform ah, ka dibna ku milmi chloroform ilaa 100ml oo qas.
Cabbir wareegga indhaha ee muunadda tijaabada 25ºC iyo 589nm dhererka hirarkaxisaabi wareegtada gaarka ah sida ku cad qaacidada la bixiyay.
[α]25D = (v×a)/[w×(1-b)]
[α]25D: wareegga gaarka ah ee imtixaankamuunad;α: wareegga lagu arkayshahaadada xagasha;w: miisaanka muunada (g);
v: mugga (ml);
b: Biyaha ku jira(%)
Daahirnimada (waxaa qoray GC)
Xaaladaha Chromatographic: Kormatography gaaska waxaa lagu qalabeeyay ololionization detector
Tiirka: SE-54, 30m×0.35mm×0.25µm
Heerkulka foornada: Heerkulka hore 120 ℃, Qabo 2 daqiiqo
Raam: 20 ℃/daq
Heerkulka: 250 ℃, Qabo 2 daqiiqo
Heerkulka duritaanka: 250 ℃
Heerkulka cabbiraha: 250 ℃ (FID)
Mugga duritaanka: 0.2µl
Xalka muunada: ku qas 1ml A4 oo leh 1ml acetone.
Habka: Duri 0.2µl ee acetone sida maran oo duub chromatogramka.Gudahachromatogram-ka laga helay dareeraha waa in aan la faragelinwaqtiga haynta ee ugu sarreysa ugu sarreysa iyo wasakhda ugu sarreysa.Marka loo eego saamiga muunada ku duriku koobi karamagaraafka oo duub chromatogramka.Soo sheeg daahirnimadatusaale ahaan habka caadiga ah ee aagga.
Xidhmada: Dhalo, Foosto, 25kg/ Foosto, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
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Shanghai Ruifu Chemical Co., Ltd. waa hormuudka soo saaraha iyo soo saaraha Ethyl (S) -4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) oo leh tayo sare leh, waa dhexdhexaad caadi ahaan isku dhafka Atorvastatin. Calcium (CAS: 134523-03-8).
Calcium Atorvastatin (CAS: 134523-03-8) [magaca ganacsiga: Lipitor] waxaa inta badan loogu talagalay daawaynta cudurada wadnaha iyo xididada dyslipidemia sababtoo ah saameynta ay ku leedahay hoos u dhigista kolestaroolka dhiigga.Atorvastatin waxay u shaqeysaa ugu horreyntii beerka.Heerarka kolestaroolka beerka oo yaraada waxay sii kordhisaa qaadashada beerka ee kolestaroolka waxayna yaraynaysaa heerarka kolestaroolka balaasmaha.Lipitor, ilaa 1996, waxa ay noqotay dawada ugu iibka fiican aduunka ilaa heerkaas.
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