Fingolimod Hydrochloride CAS 162359-56-0 Nadiifinta ≥99.0% (HPLC) API Nadaafadda Sare ee Warshada
Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Fingolimod Hydrochloride
CAS: 162359-56-0
Fingolimod Hydrochloride waa dawo ay FDA ansixisay ee daawaynta Sclerosis-ka badan.
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Fingolimod Hydrochloride |
La mid ah | Fingolimod HCl;FTY 720 |
Lambarka CAS | 162359-56-0 |
Lambarka CAT | RF-API39 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C19H34ClNO2 |
Miisaanka Molecular | 343.93 |
Meesha dhalaalaysa | 102.0 ~ 107.0°C |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa budo cad-cad |
Aqoonsiga | HPLC |
Meesha dhalaalaysa | 102.0 ~ 106.0 ℃ |
Solubility | Si Buuxda Ugu Milmayn Biyaha |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Qoyaanka (KF) | ≤0.50% |
Hadhaaga dabka | ≤0.20% |
Biraha culus | ≤20pm |
Xalalka Haraaga ah | |
Dichloromethane | ≤0.05% |
Ethyl acetate | ≤0.50% |
Ethanol | ≤0.50% |
Methanol | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Walxaha Qaraabada | |
Xumaanta Keliya | ≤0.50% |
Wadarta wasakhda | ≤1.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee Fingolimod Hydrochloride (CAS: 162359-56-0) oo leh tayo sare.
Fingolimod Hydrochloride waa daawada afka laga qaato ee ugu horreysa ee lagu daweeyo sclerosis badan.Waxaa si guul leh u soo saartay shirkadda dawooyinka ee Novartis, waxaana u oggolaatay suuqgeyntiisa Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA).Cudurka 'sclerosis' oo badan waa cudur neerfaha ah oo daciifa kaas oo keeni kara in bukaanku lumiyo dareenka dheelitirka, u muuqda murqaha muruqyada iyo cilladaha kale ee dhaqdhaqaaqa.Fingolimod Hydrochloride waa sphingosine-l-fosfate (S1PR).Fosforyaalka ka dib, waxay ku xidhan tahay s1P reseptor kaas oo ku yaala dusha sare ee lymphocyte, kaas oo bedeli doona socdaalka lymphocyte, oo kor u qaadi doona unugyada unugyada lymfatic, oo ka hortagaya lymphocytes inay ka baxaan nudaha lymphoid oo galaan tallaalka.Sidaa darteed, waxay ka ilaalin doontaa unugyadaas inay galaan habka dhexe ee neerfayaasha (CNS), taas oo ku guulaysata saameynta difaaca jirka.