Fulvestrant (ICI 182780) CAS 129453-61-8 API Sawirka Tayada Sare leh ee Warshada

Fulvestrant (ICI 182780) CAS 129453-61-8 API Tayada Sare

Sharaxaad Gaaban:

Magaca: Fulvestrant (ICI 182780)

CAS: 129453-61-8

Muuqashada: Caddaan ilaa-cad-cad budada crystalline

Qiimaynta: 97.0% ~ 102.0% (ku salaysan qalalan)

Fulvestrant waxaa loo isticmaalaa daawaynta hormoonka xasaasiga ah ee kansarka naasaha ee haweenka postmenopausal.

API Tayada Sare, Wax soo saarka Ganacsiga

Inquiry: alvin@ruifuchem.com

Email noogu soo dir

Faahfaahinta Alaabta

Alaabooyinka La Xiriira

Tags Product

Sharaxaad:

Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca: Fulvestrant
CAS: 129453-61-8
Fulvestrant waxaa loo isticmaalaa daawaynta hormoonka xasaasiga ah ee kansarka naasaha ee haweenka postmenopausal.
API Tayada Sare, Wax soo saarka Ganacsiga

Guryaha Kiimikada:

Magaca Kiimikada	Fulvestrant
La mid ah	(7α,17β) -7- [9-[(4,4,5,5,5-Pentafluorpentyl) sulfinyl] nonyl] estra-1,3,5 (10) -trien-3,17-diol;ICI 182780
Lambarka CAS	129453-61-8
Lambarka CAT	RF-API81
Heerka Saamiyada	Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram
Qaanuunka molecular	C32H47F5O3S
Miisaanka Molecular	606.77
Meesha dhalaalaysa	104.0 ~ 106.0 ℃
Solubility	Ku milmay methanol, ethanol;Aan ku milmin Biyaha
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Crystalline ee Caddaan iyo Off-White
Aqoonsiga	By IR, HPLC
Wareegga indhaha ee gaarka ah	+108.0° ilaa +115.0°
Khasaare xagga qalajinta	≤0.50%
Hadhaaga dabka	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant La Kordhiyey	≤0.30%
Fulvestrant Sterol Dimmer	≤0.80%
Shakhsi kasta oo aan la cayimin wasakhnimo	≤0.10%
Wadarta wasakhda	≤1.0%
Fulvestrant A	42.0% ~ 48.0%
Fulvestrant B	52.0% ~ 58.0%
DMF	≤620pm
Biraha culus	≤10pm
Qiimayn	97.0% ~ 102.0% (oo ku salaysan qalalan)
Kaydinta	Ku kaydi kaydka weelasha iftiinka u adkaysta ee si fiican u xidhan oo qaboojiye ah 2 ~ 8℃
Heerka Imtixaanka	USPharmacopoeia (USP) Heerka
Isticmaalka	Dib-u-qabta Estrogen-ka

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

FAQ:

Codsiga:

Fulvestrant (ICI-182780) CAS 129453-61-8, waa daawada murqaha lagu duro oo ay samaysay shirkadda AstraZeneca waxaana loo isticmaalaa daawaynta kansarka naasaha ee sare u kaca hormoonka haweenka postmenopausal.Fulvestrant waa daawada kaliya ee antiestrogen-ka ee si ballaaran loo isticmaali karo ka dib daawaynta tamoxifen ee aan lagu guulaysan.Daawadani waa nooc ka mid ah daawaynta endocrine, sidaa darteed ma keenayso wax saameyn xun oo caadi ahaan lagu arko kiimoterabiga, taasoo siinaysa u hoggaansanaanta bukaanka ilaa xad wanaagsan.Tijaabooyin badan oo kiliinig ah ayaa lagu ogaaday in 250mg Fulvestrant uu yahay mid waxtar leh oo si joogto ah ammaan u ah khadka labaad ee daaweynta kansarka naasaha ee sareeyo.Fulvestrant waa ka soo horjeeda Estrogen-ka-sameeyaha leh IC50 ee 0.94 nM ee qiimaynta unug-la'aanta.Fulvestrant waxay sidoo kale keentaa autophagy iyo apoptosis waxayna leedahay firfircooni antitumor.