Ganciclovir CAS 82410-32-0 API BW 759 GCV Kahortagga Fayraska CMV Inhibitor Tayada Sare

Ganciclovir (CAS 82410-32-0) waxaa iska leh daawooyinka fayraska ee nucleoside, oo ah nooc ka mid ah derivatives guanosine.Ganciclovir waa wakiilka fayruska ka-hortagga waalidnimo-firfircoon ee loogu talagalay infekshannada cytomegalovirus (CMV) ee aragga- ama nafta halis gelinaya ee bukaannada difaaca jirka.Waxay leedahay saameyn ballaaran oo wax ku ool ah oo wax ku ool ah oo ka hortag ah oo ku saabsan fayraska herpes waana daawada koowaad ee daaweynta caabuqa cytomegalovirus oo saameyn xooggan ku leh fayraska cagaarshow B iyo adenovirus sidoo kale.Waa homologue of acyclovir (ACV) oo leh saameynteeda ka hortagga fayraska oo la mid ah, laakiin ka xoog badan aciclovir, oo leh saameyn gaar ah oo ka hortag ah oo ku saabsan cytomegalovirus ee la xidhiidha bukaanka AIDS-ka.Waxa loo isticmaalaa daawaynta wejiga soo-bandhigidda iyo wejiga dayactirka ee bukaannada difaaca jirkooda (ay ku jiraan bukaannada AIDS-ka) ee qaba retinitis-ka cytomegalovirus.Waxa kale oo loo isticmaali karaa ka-hortagga cudurka cytomegalovirus ee bukaannada helaya xubinta taranka ama bukaanka AIDS-ka oo natiijooyin wanaagsan ka helay baaritaanka serology cytomegalovirus.

Ganciclovir (CAS 82410-32-0) waa wax-qabad heersare ah, sun-yar iyo fayraska-doorashada sare leh oo ay samaysay Shirkadda Syntex (Mareykanka).Waa daawadii ugu horreysay ee ay FDA-da Maraykanka u ogolaato daawaynta caabuqa cytomegalovirus (CMV).Syntex waxaa la siiyay xuquuqda gaarka ah ee wax soo saarka.Bishii Juun 1988, tablet-kan ayaa markii ugu horreysay la ansixiyay in lagu qoro UK, ka dibna waxaa si isdaba-joog ah u ansixiyay Faransiiska, Mareykanka, Japan, iyo Jarmalka Galbeed, Talyaaniga iyo Kanada iyo dalal kale.Ilaa dhammaadka Juun 1999, waxaa laga oggolaaday in ka badan 70 waddan iyo gobollo si looga hortago bukaannada difaaca jirka iyo caabuqa cytomegalovirus ee bukaannada xubinta taranka.Sannadkii 2002, kiniinnada Ganciclovir waxay heleen oggolaansho FDA, oo hadda la heli karo.