Glimepiride CAS 93479-97-1 Assay 98.0%~102.0% API Sawirka Nadaafadda Sare ee Warshada

Glimepiride CAS 93479-97-1 Assay 98.0%~102.0% API Nadiifnimada Sare ee Warshada

Sharaxaad Gaaban:

Magaca Kiimikada: Glimepiride

CAS: 93479-97-1

Muuqashada: Budada cad ama ku dhawaad cad

Qiimaynta: 98.0% ~ 102.0%

Glimepiride ee daaweynta Noninsulin-ku-tiirsanaanta Nooca 2 ee Sonkorowga Mellitus

API Tayada Sare, Wax soo saarka Ganacsiga

Inquiry: alvin@ruifuchem.com

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Sharaxaad:

U keeni Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Glimepiride
CAS: 93479-97-1
Glimepiride ee daaweynta Noninsulin-ku-tiirsanaanta Nooca 2 ee Sonkorowga Mellitus
API Tayada Sare, Wax soo saarka Ganacsiga

Guryaha Kiimikada:

Magaca Kiimikada	Glimepiride
La mid ah	Amaryl
Lambarka CAS	93479-97-1
Lambarka CAT	RF-API24
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C24H34N4O5S
Miisaanka Molecular	490.62
Meesha dhalaalaysa	212.2 ~ 214.5 ℃
Xaalada Maraakiibta	Heerkulka deegaanka hoostiisa
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada cad ama ku dhawaad cad
Aqoonsiga	IR (La mid ah Heerka)
Walxaha laxidhiidha
Cis-Isomer (A)	≤0.80%
Sulfonamide (B)	≤0.40%
Urethane (C)	≤0.10%
3-Isomer (D)	≤0.20%
Wax kasta oo wasakh kale ah	≤0.10%
Wadarta wasakhda	≤0.50%
Khasaare xagga qalajinta	≤0.50%
Hadhaaga dabka	≤0.10%
Biraha culus	≤0.001%
Qiimayn	98.0% ~ 102.0%
Heerka Imtixaanka	Yurub Pharmacopeia (EP);Pharmacopoeia ee Maraykanka (USP)
Isticmaalka	Walaxda Farmashiyeedka Firfircoon (API)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

FAQ:

Codsiga:

Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha iyo soo saaraha ugu horreeya ee Glimepiride (CAS: 93479-97-1) oo leh tayo sare leh, qayb dawooyin firfircoon ah (API).Glimepiride waa dawada ka hortagga sonkorowga oo gacan ka geysata xakameynta heerarka sonkorta dhiigga.Glimepiride waa falgal dheer, jiilka saddexaad ee sulfonylurea oo leh firfircooni hypoglycemic.

Glimepiride (magaca ganacsiga asalka ah ee Amaryl) waa daawada afka laga helo sulfonylurea dhexdhexaad ilaa-dheer.Sida dhammaan sulfonylureas, glimepiride wuxuu u shaqeeyaa sidii qarsoodi insulin.Waxay hoos u dhigtaa sonkorta dhiigga iyada oo kicinaysa sii daynta insulin ee unugyada beta ee ganaca ee shaqaynaya iyo iyadoo kordhinaysa dareenka unugyada durugsan ee insulinta.Glimepiride waxay u badan tahay inay ku xidho ATP-xasaasiyaha kanaalka potassium ee dusha sare ee unugga ganaca, hoos u dhigista habka potassium oo keenaya depolarization xuubka.Depolarization Membrane waxay kicisaa qulqulka kaalshiyamka ion iyada oo loo marayo kanaalada kaalshiyamka danab-ku-oolka leh.Korodhkan xoogga saarista calcium ion intracellular wuxuu keenaa dheecaanka insulinta.Glimepiride waxaa inta badan loo isticmaalaa in lagu daweeyo bukaanada qaba nooca 2 ee sonkorowga waxayna sidoo kale hoos u dhigi kartaa fursadaha in qof uu ku dhaco dhibaatooyinka nooca 2aad ee sonkorowga.Daawada waxaa ansixiyay FDA 1995 waxaana soo saaray Sanofi-Aventis.Waxaa lala isticmaali karaa cunto habboon iyo barnaamijka jimicsiga waxaana sidoo kale la isticmaali karaa kaligaa ama daawooyinka kale ee ka hortagga sonkorowga haddii loo baahdo.Glimepiride waxaa loo isticmaali karaa monotherapy ahaan ama marka lagu daro insulin.