H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Assay>99.0%

1. Guryaha: Alaabtani waa inay noqotaa budada crystalline cad.
2. Qiimee:
1) Go'aaminta Glycine Methyl Ester Hydrochloride assay
1.1 Habka
Xaaladaha aashitada hoostooda, muunadku waxa uu la falgalaa xaddi nitrate oo qalin ah, iyo nitrate-ka qalinka ah ee xad-dhaafka ah waxa lagu celiyaa ammonium thiocyanate, isaga oo tixraacaya ammonium ferric sulfate
Tilmaame ahaan, wadarta guud ee koloriin waxaa lagu go'aamiyay iyadoo loo eegayo mugga xalka caadiga ah ee la isticmaalo, wadarta guud ee koloriinta waxaa laga jaray nuxurka glycine hydrochloride si loo helo maadada Glycine Methyl Ester Hydrochloride.
1.2 Reagent
Dibutyl phthalate;
Xalka nitric acid: 2+3;
Xalka nitrate-ka qalinka ah ee titration caadiga ah: c(AgNO3) = 0.1 mol/L
Ammonium thiocyanate xal titration caadiga ah: c(NH4SCN) = 0.1 mol/L
Ammonium ferric sulfate (III) dareere tilmaame: 80 g/L
1.3 Habka Falanqaynta
Miisaanka qiyaastii 0.5g muunad, sax ah ilaa 0.0001g.Ku rid weel 250ml ah, ku milmi biyaha 40ml, ku dar 10 ml nitric acid, Ku dar (50 ± 0.02) mL silver nitrate solution, 3ml ammonium ferric sulfate solution, 4mL dibutyl phthalate, iyo thiocyanate Ammonium xal tit titrated ilaa uu xalku ahaa bunni khafiif ah oo uu midab la'aan ahaado 30 ilbiriqsi.
1.4 Xisaabinta natiijada
Jajabka tirada badan ee glycine methyl ester hydrochloric acid content w1, kaas oo lagu muujiyey sida%, waxaa loo xisaabiyaa si waafaqsan isla'egta (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 formula (1)
Halkee:
V1: Mugga nitrate-ka qalinka ah ee xalka titration caadiga ah (ml)
V2: Mugga ammonium thiocyanate xal titration caadiga ah oo ay isticmaasho titration (ml)
c1: Qiimaha saxda ah ee xalka titration heerka nitrate silver (mol/L)
c2: Qiimaha saxda ah ee ammonium thiocyanate xal titration caadiga ah (mol/L)
w2: Jajabka tirada badan (%) ee ka kooban glycine hydrochloride sida lagu go'aamiyay Qaybta 4.2
M: Cufka molar ee glycine methyl ester hydrochloride (g/mol)
1.126: Isku-beddelka isku-dhafka glycine hydrochloride ee Glycine methyl ester hydrochloride.
Qiimaha celceliska xisaabta ee laba natiijadood oo isbarbar socda ayaa loo qaatay natiijada cabbiraadda, iyo farqiga dhammaystiran ee u dhexeeya labada natiijooyinka cabbiraadda isbarbar-dhigga ah wax aan ka badnayn 0.05%.
2) Go'aaminta waxa ku jira glycine hydrochloride
2.1 Habka
Isticmaalka dimethyl jaalaha ah tilmaame ahaan, muunadda waxaa lagu titrate sodium hydroxide xal titrating heerka, iyo mugga xalka waxaa loo titrate iyadoo la raacayo isticmaalka heerka sodium hydroxide.
Xisaabi waxa ku jira glycine hydrochloride.
2.2 Reagent
Xalka titration caadiga ah ee sodium hydroxide: c (NaOH) = 0.1mol/L
Dareeraha calaamadda jaalaha ah ee Dimethyl: 10 g/L
2.3 Habka Falanqaynta
Miisaanka ku saabsan 5.0 g muunada shaybaadhka, sax ah 0.0001g, geli 200 ml oo digir ah, ku milan biyo 50ml, oo ku dar 5 dhibcood oo dimethyl
Dareere calaamad jaale ah, oo leh titration heerka titration sodium hydroxide ilaa xalka casaanka ilaa liimiga jaalaha ah uu yahay barta ugu dambeysa
2.4 Natiijooyinka Xisaabinta
Jajabka tirada w2 ee ka kooban glycine hydrochloride waxaa lagu muujiyay % waxaana loo xisaabiyaa si waafaqsan isla'egta (2):
w2 = (V/1000) cM/m *100 qaacido (2)
Halkee:
V: Mugga sodium hydroxide xal titration standard (mL)
c: Qiimaha saxda ah ee soodhiyam hydroxide heerka titration xal fiirsiga (mol/L)
M: Cufka molar ee glycine hydrochloride (g/mol)
m: Qiimaha guud ee muunada (g)
Qiimaha celceliska xisaabta ee laba natiijadood oo isbarbar socda ayaa loo qaatay natiijada cabbiraadda, iyo farqiga dhammaystiran ee u dhexeeya labada natiijooyinka cabbiraadda isbarbar-dhigga ah wax aan ka badnayn 0.05%
3. Dhibic dhalaalaysa: Marka loo eego habka go'aaminta barta dhalaalka (Pharmacopoeia Chinese 2010 Lifaaqa VIC), kala duwanaanshaha barta dhalaalka waa 172-178ºC.
4. Miisaanka qallajinta: qaado alaabtan 105.0 ℃ oo u qalaji miisaan joogto ah.Miisaanku waa inuusan ka badnaan 0.5%.
5. Kaydinta: Alaabtan waa in lagu qaboojiyaa meel ka fog iftiinka.