Histrelin Acetate CAS 76712-82-8 Peptide Purity (HPLC) ≥98.0% Warshada
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee Histrelin Acetate (CAS: 76712-82-8) oo leh tayo sare.Kiimikada Ruifu waxay bixisaa taxane ah peptides GMP.Ruifu waxa uu bixin karaa keenista aduunka oo dhan, qiimo tartan ah, tiro yar iyo tiro badan oo la heli karo.Iibso Histrelin Acetate,Please contact: alvin@ruifuchem.com
Magaca Kiimikada | Histrelin acetate |
La mid ah | Histrelin;Histrelin Acetic Acid Salt;Magaca supprelin (Roberts Pharmaceutical);[des-Gly 10, D-His(Bzl) 6]-LH-RH Ethylamide;5-oxo-L-Prolyl-L-Histidyl-L-Tryptophyl-Lseryl-L-Tyrosyl-Nt-Benzyl-D-Histidyl-L-Leucyl-L-Arginyl-N-Ethyl-L-Prolinamide Diacetate |
Tixraaca Peptide | Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt Acetate Salt |
Foomka milixda | Acetate |
Heerka Saamiyada | Suuqa dhexdiisa, Miisaanka Ganacsiga |
Lambarka CAS | 76712-82-8 |
Qaanuunka molecular | C66H86N18O12 |
Miisaanka Molecular | 1323.52 g/mol |
Cufnaanta | 1.46±0.10 g/cm3 |
Xasaasi ah | HygroscopicQoyaanka xasaasiga ah |
Heerkulka Kaydinta | Qabow & Meel Qalalan (2 ~ 8 ℃).Qaboojiyaha |
COA & MSDS | La heli karo |
Qaybta | GMP Peptides |
Nolosha shelf | 24 bilood laga bilaabo taariikhda wax soo saarka haddii si sax ah loo kaydiyo |
Summada | Kiimikada Ruifu |
Walxaha | Heerarka Kormeerka | Natiijooyinka |
Muuqashada | Budada Lyophilized White | waafaqsan |
Solubility | Ku milmay biyaha ama 1% acetic acid marka la uruuriyo ≥1mg/ml si loo siiyo xal aan midab lahayn | waafaqsan |
MS | Monoisotopic Mass: 1323 ± 1.0 | 1323.1 |
Aqoonsiga HPLC | Si la mid ah Xalka Tixraaca | waafaqsan |
Falanqaynta Amino Acid | Ser: hadda | waafaqsan |
Glu: 0.85 ~ 1.1 | 0.95 | |
Pro: 0.85 ~ 1.1 | 1.05 | |
Leu: 0.85 ~ 1.1 | 1.01 | |
Tir: 0.85 ~ 1.1 | 1.00 | |
Isaga: 1.70 ~ 2.2 | 0.99 | |
Arg: 0.85 ~ 1.1 | 0.98 | |
Trp: hadda | Go'aansaday | |
Nadiifinta Peptide (HPLC) | ≥98.0% | 99.58% |
Walxaha La Xiriira (HPLC) | Wadarta wasakhda (%) ≤2.0% | 0.42% |
Wax kasta oo wasakh kale ah ≤1.0% | 0.24% | |
Waxyaabaha Acetate (HPLC) | ≤12.0% | 11.5% |
Waxyaabaha Biyaha ka kooban (Karl Fischer) | ≤5.0% | 1.0% |
Qiimayn | 95.0 ~ 105.0% (Anhydrous, Acid Asiidh bilaash ah) | 98.5% |
Asal ahaan Alaabta | Synthetic | |
Fiiro gaar ah | Kaliya Cilmi-baaris, Maaha Isticmaalka Aadanaha | |
Gabagabo | Alaabta waa la tijaabiyay oo waafaqay qeexitaannada |
Xidhmada:Fiilada caaga ah (oo loogu talagalay xirmooyinka peptide) ama dhalo dhalada ah, tirada sida waafaqsan shuruudaha tafatirka macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xidhan meel qabow oo engegan (2 ~ 8℃) bakhaar ka fog walxaha aan ku haboonayn.Ka ilaali iftiinka iyo qoyaanka.
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Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
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Xeerarka Khatarta
60 - Waxa ay wiiqi kartaa dhalmada
Sharaxaada Badbaadada
S53 - Iska ilaali soo-gaadhista - hel tilmaamo gaar ah kahor isticmaalka.
S22 - Ha neefsan boorka.
S36/37/39 - Xidho dhar ilaalin ku haboon, galoofyada iyo ilaalinta indhaha/wejiga.
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WGK Germany 3
RTECS OK6370800
Histrelin Acetate (CAS: 76712-82-8), hormoonka gonadotrophin-sii daynta hormoonka (GnRH), agonist, ayaa loo soo bandhigay sidii daawaynta safka hore ee daaweynta baaluqnimada dhexe ee hore.Marka la maamulo muddo dheer, waxay xakameysaa sii-deynta gonadotrophin, waxay joojisaa steroidogenesis ugxan-sidaha iyo xiniinyaha, waxayna ka hortagtaa korriinka galmada.Ka sarreeya daawaynta dhaqameed ee wakiilada progestational, histrelin waxay u muuqataa inay leedahay saameyn hoos u dhac ku ah korriinka lafaha taasoo u oggolaanaysa korriin heersare ah oo si weyn u kordhay dhererka ugu dambeeya ee qaangaarka.Histrelin ayaa sidoo kale loo isticmaalay in lagu daweeyo xanuunada kale oo ay ku jiraan endometriosis, polycystic ugxansidaha, uterine leiomyomas, premenstrual syndrome daran iyo si looga hortago porphyria ba'an intermittent.
Qeexitaan: oligopeptide ka kooban pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, iyo haraaga N-ethylprolinamide oo isku xiga.Waa analooga nonapeptide synthetic ee gonadotro in-sii daynta hoormoonka, waxaana loo isticmaalaa sida maqaar-galaha hydrogel subcutaneous (gaar ahaan sida cusbada diacetate) ee daaweynta kansarka qanjirka 'prostate' iyo xakamaynta wax soo saarka hoormoonka galmada gonadal ee carruurta leh baaluq dhexe ee precocious.Loo isticmaalo baaluqnimada hore.
Ficilada Biochem/Physiol: Histrelin Acetate waa GnRH (hormoonka sii-deynta hormoonka) agonist, histerelin.GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), oo sidoo kale loo yaqaan LHRH (hormoonka sii daaya hormoonka luteining) ama gonadorelin, ayaa muhiim u ah taranka naasaha waxaana laga sii daayaa hypothalamic neurons.Waxay mas'uul ka tahay dheecaanka gonadotropins, hormoonka luteining (LH) iyo hoormoonka follicle-stimulating hormone (FSH), oo ka yimaada qanjidhada pituitary.Isbeddellada ku jira GnRH waxay la xiriiraan normosmic hypogonadotropic hypogonadism.Histerelin waxaa loo isticmaalaa daawaynta baaluqnimada dhexe ee carruurta.Waxay ka hortagtaa ficilada steroids-ka galmada ee xubnaha taranka ee labka iyo dheddigga.
Waxa loo heli karaa sidii muruqa-muruqa maalin kasta lagu duro.Histrelin waxa kale oo laga heli karaa gudaha 12-bilood ee maqaar-galaha subcutaneous (Vantas) ee daawaynta palliative ee kansarka qanjirka 'prostate' (ilaa 2005 gudaha Maraykanka, iyo tan iyo Jan 2010 gudaha UK. 12 bilood ah implant subcutaneous (Supprelin LA) loogu talagalay bartamaha precocious qaan-gaarnimada (CPP) waxaa ansixiyay Maajo 3, 2007 Maamulka Cuntada iyo Dawooyinka ee Mareykanka.