Ibrutinib Deacryloylpiperidine CAS 330786-24-8 daahirnimo>99.0% (HPLC)

Sharaxaad Gaaban:

Magaca Kiimikada: Ibrutinib Deacryloylpiperidine

CAS: 330786-24-8

Daahirsanaanta:>99.0% (HPLC)

Muuqashada: Off-White to Khaki Powder

Dhexdhexaadka Ibrutinib (CAS: 936563-96-1)

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Alaabooyinka La Xiriira

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Sharaxaad:

Dhexdhexaadiyeyaasha la xidhiidha Ibrutinib:
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxyphenylboronic Acid CAS 51067-38-0
Ibrutinib Dhexdhexaad N-2 CAS 330786-24-8
Ibrutinib Dhexdhexaad N-3 CAS 330792-70-6
Ibrutinib CAS 936563-96-1

Guryaha Kiimikada:

Magaca Kiimikada	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
La mid ah	Ibrutinib dhexdhexaadiyaha N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib wasakhnimo 8;5- (4-Phenoxyphenyl) -7H-pyrrolo [2,3-d] pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl wasakh
Lambarka CAS	330786-24-8
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C17H13N5O
Miisaanka Molecular	303.32
Meesha dhalaalaysa	>262℃(dac.)
Cufnaanta	1.380± 0.06 g/cm3
Heerka khatarta	6.1;Sun
Kooxda Baakadaha	III
COA & MSDS	La heli karo
Asal ahaan	Shanghai, Shiinaha
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Off-White ilaa budada Khaki
Aqoonsiga	HNMR, LC-MS
Daahirnimada / Habka Falanqaynta	>99.0% (HPLC)
Khasaare xagga qalajinta	<1.00%
Hal Max.wasakhnimo	<1.00%
Wadarta wasakhda	<1.00%
Biraha culus (sida Pb)	<20ppm
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadka Ibrutinib (CAS: 936563-96-1)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.

Faa'iidooyinka

FAQ:

330786-24-8 - Codsiga:

3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine (CAS: 330786-24-8) waa dhexdhexaadiye synthetic ah oo faa'iido leh ee isku-dhafka Ibrutinib (CAS: 936563-96-1) ).Ibrutinib waa nooc ka mid ah Bruton tyrosine kinase (BTK) inhibitor, waxaa loo isticmaali karaa daaweynta lymphocytic leukemia raaga (CLL) iyo mantle cell lymphoma (MCL).MCL iyo CLL waxay ka tirsan yihiin B-cell non-Hodgkin's lymfoma, taas oo ay adag tahay in la daweeyo oo ay fududahay in ay soo noqnoqdaan.Dawaynta kiimikaad ee caadiga ah ma laha bartilmaameedka, badanaa waxay dhacdaa 3 ama 4 falcelin xun.Ibrutinib iyo B lymphocytes waxay bartilmaameedsan karaan BTK oo lagama maarmaan u ah samaynta, kala soocida, iyo gudbinta macluumaadka, waxay joojiyaan dhaqdhaqaaqa BTK si aan leexleexad lahayn, waxayna u diidaan faafinta unugyada burooyinka iyo badbaadada si wax ku ool ah.Ibrutinib si dhakhso ah ayaa loo nuugi karaa ka dib maamulka afka, inta lagu jiro 1 ~ 2h waxay gaaraan heerka ugu sarreeya ee dhiigga, falcelinta xun waxay ka tirsan tahay hal ama laba, sidaas darteed, Ibrutinib wuxuu noqon doonaa doorasho cusub oo lagu daweeyo CLL iyo MCL.