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N- (2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Dhexdhexaad Nadiif Sare Oo Lasoo Bandhigay
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Dhexdhexaad Sare nadiif ah

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Dhexdhexaad Sare nadiif ah

Sharaxaad Gaaban:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8

Muuqashada: Jaale ama ku dhawaad ​​budada jaalaha ah

Daahirsanaanta: ≥98.0% (HPLC)

Dhexdhexaadinta Imatinib Mesylate (CAS: 220127-57-1) ee daawaynta Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph+CML)

Tayada Sare, Wax Soo Saarka Ganacsiga

Inquiry: alvin@ruifuchem.com


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Alaabooyinka La Xiriira

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Sharaxaad:

Sahayda Ganacsiga Imatinib Mesylate iyo Dhexdhexaadiyayaasha la xidhiidha:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N- (5-Amino-2-methylphenyl) -4- (3-pyridyl) -2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl] benzoic acid dihydrochloride CAS: 106261-49-8

Guryaha Kiimikada:

Magaca Kiimikada N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
La mid ah Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Lambarka CAS 152460-09-8
Lambarka CAT RF-PI228
Heerka Saamiyada Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular C16H13N5O2
Miisaanka Molecular 307.31
Meesha dhalaalaysa 188.0-193.0 ℃
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Jaalle ama ku dhawaad ​​budada jaalaha ah
daahirnimo ≥98.0% (HPLC)
Qoyaanka (KF) ≤0.50%
Wadarta wasakhda ≤2.0%
Xumaanta Keliga ah ee ugu badan ≤1.0%
Hadhaaga dabka ≤0.50%
Biraha culus ≤20pm
Heerka Imtixaanka Heerka Ganacsiga
Isticmaalka Dhexdhexaadka Imatinib Mesylate (CAS: 220127-57-1)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada bireed aluminium, durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka

1

FAQ:

Codsiga:

Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) tayo sare leh.Waa dhex dhexaad caadi ahaan ku jira isku-dhafka Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate waa unug yar oo ka hortagaya c-Abl protein-tyrosine kinase, Aad u gaar ah BCR-ABL, enzyme la xidhiidha kansarka myelogenous leukemia (CML) iyo noocyo gaar ah oo lymphoblastic leukemia ba'an (ALL).Dhacdo tarjumaad ah oo u dhaxaysa koromosoomyada 9 iyo 22 waxay soo saartaa koromosoomyada Philadelphia, ka dibna waxay soo saartaa borotiinka fusion Bcr-Able leh firfircoonida kinase aberrant taasoo kor u qaadaysa kororka unugyada degdega ah.Imatinib Mesylate wuxuu xiraa kinase-kan muhiimka ah, isagoo joojinaya koritaanka CML ee la xiriira.Imatinib Mesylate ayaa sidoo kale la soo bandhigay si loo joojiyo PDGFR iyo tyrosine kinases ee la xidhiidha c-Kit.Daawooyinka ka kooban Imatinib Mesylate ayaa loo isticmaalay daawaynta kansarrada kala duwan.

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