Indapamide CAS 26807-65-8 Nadiifinta ≥99.5% (HPLC) API EP Heerka Warshada Tayada Sare
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha iyo soo saaraha ugu horreeya ee Indapamide iyo dhexdhexaadiyeyaasha la xidhiidha tayada sare leh.
Indapamide CAS 26807-65-8
2-Methylindoline CAS 6872-06-6
1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
| Magaca Kiimikada | Indapamide |
| La mid ah | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
| Lambarka CAS | 26807-65-8 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C16H16ClN3O3S |
| Miisaanka Molecular | 365.83 |
| Meesha dhalaalaysa | 160.0 ~ 162.0 ℃ |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ama ku dhawaad cad budada crystalline |
| Solubility | Dhab ahaantii Biyo Aan Ku milmin;Ku milmay Ethanol |
| Aqoonsiga A | Ultraviolet iyo Spectrophotometry Nuugista Muuqda ee Muuqda |
| Aqoonsiga B | Spectrophotometry Nuugista Infrared |
| Aqoonsiga C | Chromatography oo lakab khafiif ah |
| Wareegga indhaha | -0.80°~ +0.80° (C=5, C2H5OH) |
| Biyaha (EP 2.5.12) | <3.00% |
| Dash sulfateed (EP 2.4.14) | <0.10% |
| Biraha culus (EP 2.4.8) | <10pm |
| Walxaha laxidhiidha | |
| Xumaanta B | <0.30% |
| Xumaan aan la cayimin | <0.10% |
| Wadarta wasakhda | <0.50% |
| Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) |
| Heerka Imtixaanka | Heerka EP |
| Isticmaalka | API;Antihypertensive iyo A Diuretic |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Indapamide (CAS: 26807-65-8) waa antihypertensive iyo durayo.Iyada oo la joojinayo dib u nuugista Na+ ee dhamaadka u dhow ee tuubooyinka isku dhafka ah ee fog, waxay soo saartaa saameyn dareere ah waxayna sidoo kale xannibtaa qulqulka Ca2+.Waxay leedahay xulashada sare ee muruqa siman ee xididdada dhiigga, waxay ballaadhisaa maraakiibta yaryar ee durugsan waxayna soo saartaa saameyn hypotensive.Laakiin saameynta muruqyada siman ee xididdada xididdada dhiigga ayaa ka sii xoog badan saamaynta duritaanka, ka hooseeya qiyaasta diuretic waxay hoos u dhigi kartaa, qiyaaso sare waxay muujiyeen saameyn durduriyaha, laakiin ma jiraan cilladaha diuretic thiazide, kuwaas oo aan keenin hypotension orthostatic, dareeraha iyo tachycardia milicsiga, sawirka dhiigga, dheef-shiid kiimikaadka dhiigga dufanka, sonkorta iyo shaqada kelyaha sidoo kale ma yeelan wax saameyn ah oo muuqda, qiyaasaha daaweynta ee garaaca wadnaha, wax soo saarka wadnaha, wax isbeddel ah oo la taaban karo oo ku yimaada electrocardiogram (ecg) waxay ahaayeen wax saameyn ah oo muuqda oo ku saabsan habka dhexe ee neerfayaasha iyo neerfaha madaxbannaan.Maamulka afka 2 ~ 3 buuga kiimikaad H waxa uu soo saaray saamayn hypotensive, kaas oo la dayactiray 24h.Saamaynta diuretic waxay soo muuqatay 3h waxayna gaadhay saamaynta ugu badan ee 4 ~ 6h.Indapamide waxay ku habboon tahay dhiig-karka hoose ee dhexdhexaadka ah iyo dhexdhexaadka ah, sidoo kale waxaa loo isticmaali karaa wadne-gabka wadnaha ee ay sababto haynta sodium biyaha, oo leh cillad kelyaha ayaa sidoo kale lagu dabaqi karaa bukaannada qaba dhiig-karka, sonkorowga, hyperlipidemia, isticmaalka saameynta antihypertensive waa mid cajiib ah.
