Silsiladda Dhexe ee Irbesartan Hydrochloride CAS 151257-01-1 Nadiif> Warshada 99.0% (HPLC)
Qalabka Kiimikada ee Ruifu Dhexdhexaadiyaha Irbesartan:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tril Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Side Hydrochloride CAS 151257-01-1
Magaca Kiimikada | 2-Butyl-1,3-diazaspiro[4.4] aan-1-en-4-hal Hydrochloride |
La mid ah | Irbesartan Side Side Hydrochloride;Irbesartan Lactam wasakh;Irbesartan wasakh A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-hal Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4] aan-1-en-4-hal HCl |
Lambarka CAS | 151257-01-1 |
Lambarka CAT | RF-PI1894 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C11H18N2O·HCl |
Miisaanka Molecular | 230.74 |
Ku milmay biyaha | Ku milmay Biyaha |
Meesha dhalaalaysa | 235.0 ~ 240.0 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa ku dhawaad cad budada crystalline |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.20% |
Wadarta wasakhda | <1.00% |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexe ee Irbesartan (CAS: 138402-11-6) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
2-Butyl-1,3-diazaspiro[4.4] non-1-en-4-one Hydrochloride (CAS: 151257-01-1), sidoo kale loo yaqaan Irbesartan Side Chain Hydrochloride, waa Dhexdhexaadiyaha Irbesartan (Avapro) (CAS). : 138402-11-6).Irbesartan waa angiotensin II reseptor inhibitor, angiotensin II reseptors waxaa loo qaybiyaa AT1, AT2, irbesartan waxay joojin kartaa AngⅠ isu beddelka AngII iyadoo la xushay xannibaadda AT1 reseptor ee AngII, gaar ahaan antagonize angiotensin beddelidda enzyme 1 reseptor (AT1 of 50AT1) jeer ka badan kan AT2, waxay joojin kartaa vasoconstriction iyo aldosterone siideynta iyada oo si xushmad leh u xannibaysa xidhitaanka AngII oo leh soo-dhoweeyaha AT1 waxayna keenaysaa saameynta antihypertensive.Alaabtani ma joojiso angiotensin-beddelka enzyme (ACE), renin, iyo hormoonnada kale ee soo-qabtayaasha, mana xakameeyo nidaamka cadaadiska dhiigga iyo dheellitirka kanaalka sodium ion.Irbesartan waxay sidoo kale yareyn kartaa dib u habeynta korantada ee myocardium, sidaas darteed waxay yareysaa heerka dhimashada bukaanada qaba hypertension, waa daawada ugu waxtarka badan ee daaweynta hypertension iyo cudurada wadnaha.