Irinotecan Saldhig Bilaash ah CAS 97682-44-5 Assay ≥99.0% (HPLC) API Nadiifnimada Sare ee Warshada
Soo saaraha soo saaraha Irinotecan iyo Dhexdhexaadiyayaasha la xidhiidha:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Saldhigga Bilaashka ah CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Magaca Kiimikada | Saldhigga Bilaashka ah ee Irinotecan |
| Lambarka CAS | 97682-44-5 |
| Lambarka CAT | RF-API51 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C33H38N4O6 |
| Miisaanka Molecular | 586.68 |
| Meesha dhalaalaysa | 222.0-223.0 ℃ |
| Xaalada Maraakiibta | Heerkulka deegaanka hoostiisa |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Jaallaha fudud |
| Aqoonsiga HPLC | Wakhtiga haynta ee muunadu waxay u dhigantaa tan RS |
| Khasaare xagga qalajinta | ≤5.0% |
| Hal Max.wasakhnimo | ≤0.25% |
| Wadarta wasakhda | ≤1.0% |
| Qiimayn | ≥99.0% (HPLC) |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Saldhigga bilaashka ah ee Irinotecan waa kamptothecin analoog iyo topoisomerase I inhibitor.Waxay joojin kartaa AChE.Irinotecan Saldhigga bilaashka ah waxaa loo isticmaalaa in lagu daweeyo kansarka mindhicirka, laakiin sidoo kale waxay dhexdhexaadisaa joojinta kala-soocidda unugyada dendritic waxayna hoos u dhigtaa tirada maraakiibta burooyinka ee moodooyinka glioma.Irinotecan waxay ka hortagtaa u-diridda xudunta DNA-da iyadoo ku xidhan topoisomerase I-DNA complex.Samaynta kakan ternary waxa ay faragalisaa fargeetada taranka ee dhaqaaqa, taas oo keenta qabashada taranka iyo dildilaaca laba-geesoodka ah ee DNA-da.
