L-Glutamine CAS 56-85-9 (H-Gln-OH) Qiimaynta 99.0 ~ 101.0% Warshada Tayada Sare

Farmashiyaha JabbaanHeerarka Tixraaca
L-Glutamine [56-85-9]
L-Glutamine, marka la qalajiyo, waxay ka kooban tahay wax aan ka yarayn 99.0% oo aan ka badnayn 101.0% L-Glutamine (C5H10N2O3).
Sharaxaada L-Glutamine waxay u dhacdaa sida caddaan, kiristaalo ama budo crystalline ah.Waxay leedahay dhadhan sifo yar
Waxay si xor ah ugu milmaysaa aashitada formic, waxay ku milmi kartaa biyaha, iyo ficil ahaan aan lagu milmi karin ethanol (99.5)
Aqoonsiga Go'aami nooca nuugista infrared ee L-Glutamine sida lagu faray habka potassium bromide disk ee hoos yimaada Infrared Spectrophotometry <2.25>, oo barbar dhig spectrum iyo Spectrum tixraaca: labada spectra waxay muujinayaan xoojinta nuugista isku midka ah ee tirooyinka hirarka isku midka ah.
Wareegga indhaha <2.49> [a] 20D:+6.3° ilaa +7.3° Si sax ah u miisaan qiyaastii 2 g oo L-Glutamine ah, oo hore loo qalajiyey, ku dar 45mL oo biyo ah, diiri ilaa 40℃ si ay u milmaan, ka dib qaboojinta, ku dar biyo si aad u samayso sax ah 50 ml.Go'aami wareegga indhaha ee xalkan unug 100-mm ah, 60 daqiiqo gudahood.
pH <2.54> pH ee xalka loo diyaariyey iyadoo lagu milmay 1.0 g oo L-Glutamine ah 50 ml oo biyo ah waxay u dhaxaysaa 4.5 iyo 6.0.
daahirnimo
(1) Cadnaanta iyo midabka xalka - Xalka lagu helay in lagu milo 0.5 g oo L-Glutamine ah 20 ml oo biyo ah waa cad yahay oo aan midab lahayn.
(2) Chloride <1.03> —Ku samee tijaabada 0.5 g oo L-Glutamine ah.Ku diyaari xalka xakamaynta 0.30 ml oo ah 0.01 mol/L hydrochloric acid VS (aan ka badnayn 0.021%).
(3) Sulfate <1.14>—Ku samee tijaabada 0.6 g oo ah L-Glutamine.Ku diyaari xalka xakamaynta 0.35 mL ee 0.005 mol/L sulfuric acid VS (aan ka badnayn 0.028z).
(4) Ammonium <1.02>-Ku samee tijaabada 0.10 g oo L-Glutamine ah, adoo isticmaalaya distillation hoos-u-dhigis cadaadis.Ku diyaari xalka xakamaynta 10.0 mL ee Xalka Ammonium ee caadiga ah.Heerkulka biyaha qubeyska waa 45 ℃ (aan ka badnayn 0.1%)
(5) Biraha culus <1.07>-ku wad 1.0 g ee L-Glutamine sida waafaqsan Habka 1, oo samee tijaabada.Ku diyaari xalka xakamaynta 1.0 mL ee Xalka Lead Heerka (aan ka badnayn 10 ppm).
(6) Birta <1.10>-Ku diyaari xalka tijaabada 1.0 g ee L-Glutamine sida waafaqsan Habka 1, oo samee tijaabada si waafaqsan Habka A. ppm)
(7) Walxaha laxidhiidha-Mila 0.10 g ee L-Glutaminein 10 ml oo biyo ah, oo u isticmaal xalkan sida xalka muunada.Dhuumaha 1 mL ee xalka muunada, ku dar biyo si aad u samayso 10 ml oo sax ah.Dhuumaha 1 mL ee xalkan, ku dar si sax ah 50 ml oo biyo ah, oo u isticmaal xalkan sida xalka caadiga ah.Ku samee tijaabada xalalkan sida lagu faray Chromatography-ka khafiifka ah <2.03>.Bar 5mL mid kasta oo ka mid ah muunadda muunada iyo xalalka caadiga ah saxan silicagel ah oo loogu talagalay chromatography-daaha khafiifka ah.Ka dibna ku samee isku-darka 1-butanol, biyo iyo acetic acid (100) (3: 1: 1) ilaa 10 cm, ku qalaji saxanka 80 ℃ 30 daqiiqo.Si siman ugu daadi xal ninhydrin ah oo isku dar ah methanol iyo acetic acid (100) (97:3) (1 100kiiba) saxanka dushiisa, oo kulayl 80℃ 10 daqiiqo: meesha aan ahayn meesha ugu muhiimsan ee laga helay xal muunad ah kama badna meesha lagu helay xalka caadiga ah.
Khasaaraha qallajinta <2.41> In aan ka badnayn 0.3% (1 g, 105 ℃, 3 saacadood)
Hadhaaga dabka <2.44> In aan ka badnayn 0.10%(1 g).
Assay Si sax ah u miisaan qiyaastii 0.15 g oo L-Glutamine ah, oo hore loo qalajiyey, ku milmi 3 mL ee formic acid, ku dar 50 mL oo acetic acid (100), iyo titrate <2.50> oo leh 0.1 mol/L perchloric acid VS (titration potentiometric).U samee go'aan madhan si la mid ah, oo samee wixii sixid ah oo lagama maarmaan ah.
ml kasta oo ah 0.1 mol/L perchloric acid VS ＝14.61 mg ee C5H10N2O3
Weelasha iyo Weelasha Kaydinta - Weelasha adag.

Heerarka Tixraaca USP <11>-USP Glutamine RS.
Aqoonsiga, Nuugista Infrared <197K>.
Wareeg gaar ah <781S>: inta u dhaxaysa +6.3° iyo +7.3°, waxaa lagu go'aamiyey 20℃
Tijaabada Xalka- Ku jira weel ku habboon, si sax ah ugu diyaari xal qiyaastii 40mg halkii ml oo biyo ah qiyaastii 40 ℃.Qabooji oo ku mil biyo ilaa mugga kahor isticmaalka.
Khasaaraha qallajinta <731>Ku qalaji 105 ℃ 3 saacadood;waxay luminaysaa wax aan ka badnayn 0.20% miisaankeeda.
Hadhaaga dabka <281>In aan ka badnayn 0.30%
Chloride <221>-Qayb 0.7-g ah ma muujinayso koloriin ka badan oo u dhiganta 0.50ml ee 0.020 N hydrochloric acid: aan ka badnayn 0.05% ayaa la helay.
Sulfate <221>-Qayb 0.8-g ah ma muujinayso wax ka badan sulfate marka loo eego 0.25ml ee 0.020 N sulfuric acid: aan ka badnayn 0.03% ayaa la helay.
Nadiifnimada Chromatographic
Adsorbent: 0.25-mm lakabka silica jel chromatographic ah.
Xalka Tijaabada: 10mg halkii ml, biyo
Halbeegga Xalka-U diyaari xalka USP Glutamine RS ee biyaha iyadoo la og yahay in la og yahay oo ku saabsan 0.05mg halkii ml.
Codsiga Mugga: 5μL
Horumarinta Habka Xalalka: isku dhafka khamriga butyl, biyo, iyo glacial acetic acid (3:1:1).
Daawada Reagent-Ku mil 0.2g oo ninhydrin ah 100ml oo isku dhafka alkohol butyl ah iyo 2 N acetic acid (95:5)
Habka-u wad sida lagu faray chromatography-ka khafiifka ah ee hoos timaada Chromatography <621>, ka dibna ku qalaji saxanka 80℃ 30 daqiiqo.Ku buufin saxanka kula buufinta, kulayl 80 ℃ 10 daqiiqo, oo ku baadh iftiinka cad hoostiisa: ma jirto meel labaad oo ku jirta chromatogram-ka laga helay xalka tijaabada oo ka weyn ama ka xoog badan meesha ugu muhiimsan ee chromatogram-ka laga helay xalka standrad (0.5%)
Waxyaalaha wasakhaysan ee Dabiiciga ah, Habka I <467>: Buuxi shuruudaha.
AsssyKu wareeji qiyaastii 150mg oo Glutamine ah, oo si sax ah loo miisaamay, ilaa galaas 125ml ah, ku milmi 3ml of formic acid iyo 50ml ee glacial acetic acid, iyo titrate leh 0.1 N perchloric acid VS go'aaminta dhamaadka dhamaadka awood ahaan.Samee go'aan maran, oo samee sixitaan kasta oo lagama maarmaan ah (eeg Titrimetry<541>).ml kasta oo ah 0.1 N perchloric acid waxay u dhigantaa 14.615 mg ee C5H10N2O3