Lenvatinib Mesylate Intermediate CAS 205448-65-3 daahirnimo>98.0% (HPLC) Warshada

Sharaxaad Gaaban:

Magaca Kiimikada: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Daahirsanaanta:>98.0% (HPLC)

Muuqashada: Caddaan-ka-baxsan ilaa budada jaalaha ah

Dhexdhexaadiyaha Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com


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Alaabooyinka La Xiriira

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Sharaxaad:

Guryaha Kiimikada:

Magaca Kiimikada Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
La mid ah 1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;Dhexdhexaadiyaha Lenvatinib 3
Lambarka CAS 205448-65-3
Lambarka CAT RF-PI1973
Heerka Saamiyada Kaydka dhexdiisa, Awoodda Wax-soo-saarka 50 MT/Sannadka
Qaanuunka molecular C12H11NO4
Miisaanka Molecular 233.22
Barta Karsan 421.0 ± 45.0 ℃
Cufnaanta 1.267 ± 0.060 g / cm3
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Ka-bax-cad ilaa budada jaalaha ah
Daahirnimada / Habka Falanqaynta >98.0% (HPLC)
Khasaare xagga qalajinta <1.00%
Hadhaaga dabka <0.50%
Wadarta wasakhda <2.00%
H-NMR Waafaqsan Qaab-dhismeedka
Heerka Imtixaanka Heerka Ganacsiga
Isticmaalka Dhexdhexaadiyeyaasha Daawooyinka

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka

1

FAQ:

Codsiga:

Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) waa dhexe ee Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, oo lagu iibiyo magaca astaanta Lenvima iyo kuwa kale, waa dawo ka hortagga kansarka oo loogu talagalay daawaynta noocyada kansarka tayroodhka qaarkood iyo kansarrada kale sidoo kale.Waxaa soo saaray Eisai Co. waxayna u shaqeysaa sidii dhowr kinase inhibitor lid ku ah VEGFR1, VEGFR2 iyo VEGFR3 kinases.Lenvatinib waxaa loo oggolaaday (ilaa 2015) daaweynta kansarka qanjirka tayroodh ee kala duwan kaas oo ah mid gudaha ku soo noqnoqda ama metastatic, horumarsan, oo aan ka jawaabin daaweynta iodine radioactive (radioiodine).Bishii Maajo 2016, Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA) ayaa ansixiyay (oo ay weheliso everolimus) daaweynta kansarka unugyada kelyaha ee horumarsan ka dib hal daawaynta kahortagga angiogenic.Daawadu waxa kale oo laga oggolaaday Maraykanka iyo Midowga Yurub kansarka hepatocellular kansarka aan laga saari karin qaliinka bukaanada aan helin daawaynta kansarka afka ama duritaanka.

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