Levosimendan Dhexdhexaadka CAS 36725-28-7 daahirnimo>99.5% (HPLC) Warshada

6- (4-Aminophenyl) -4,5-Dihydro-5-Methyl-3(2H) -Pyridazinone (CAS: 36725-28-7) waa dhexe ee Levosimendan (CAS: 141505-33-1).Levosimendan waxaa lagu soo bandhigay gudaha Iswiidhan sidii faleebo iv ah oo loogu talagalay daawaynta wadne-gabka degdega ah ama calaamadaha dib-u-celinta ee wadno-gabka joogtada ah ee xaaladaha aan daawaynta caadiga ah (tusaale, diuretic ama ACE inhibitor) ku filnayn.Waxa kale oo ay kicisaa ventricular iyo arterial adenostne triphosphate-regulated channels potassium kaas oo sababa vasodilatation ee muruqa siman ee xididdada dhiigga waxayna ka ilaalisaa myocardium ka hortagga faleebo.Fosfodiesterase III hoos u dhigista dhaqdhaqaaqa waxay u badan tahay inaysan mas'uul ka ahayn saameynteeda inotropic, lusitropic iyo faafinta togan.Si ka duwan daawooyinka kale ee cardiotonic, levosimendan waxay awood u leedahay inay soo saarto saameyn togan oo inotropic ah iyada oo aan la dheerayn nasashada myocardial ama kordhinta dhacdooyinka arrthmias malignantiga ah.Waxaa kiliinikada lagu muujiyay in ay hoos u dhigto khatarta dhimashada bukaanada qaba wadne xanuunka marka la barbar dhigo placebo iyo dobutamine.Maadaama ay leedahay awood weyn, levosimendan hadda waxay ku socotaa qiimayn caafimaad oo dheeraad ah oo ah daaweyn dabadheeraad ah oo loogu talagalay wadno-qabsiga wadnaha.