Linagliptin CAS 668270-12-0 Nadiifinta ≥99.0% (HPLC) Warshada
Soo-saarka wax-soo-saarka, Nadiifinta Sare, Wax-soo-saarka Ganacsiga
Magaca Kiimikada: Linagliptin
CAS: 668270-12-0
Magaca Kiimikada | Linagliptin |
La mid ah | BI-1356;8-[(3R) -3-Amino-1-piperidinyl] -7- (2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H -purine-2,6-dione |
Lambarka CAS | 668270-12-0 |
Lambarka CAT | RF-API105 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C25H28N8O2 |
Miisaanka Molecular | 472.54 |
Meesha dhalaalaysa | 197.0 ilaa 200.0 ℃ |
Solubility | Ku milmay DMSO |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ama Banaan-cad budada Crystalline |
NMR | Waafaqsan Qaab-dhismeedka |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Khasaare xagga qalajinta | ≤0.50% |
Hadhaaga dabka | ≤0.10% |
Biraha culus | ≤10pm |
Walxaha laxidhiidha | |
Xumaanta Keliya | ≤0.50% |
Wadarta wasakhda | ≤1.0% |
Isomer | ≤0.15% |
Xalalka Haraaga ah | |
Methanol | ≤3000pm |
Isopropanol | ≤5000ppm |
DMF | ≤800pm |
Dichloromethane | ≤600pm |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Linagliptin (CAS: 668270-12-0) waa ka hortag DPP-4 oo ay samaysay Boehringer Ingelheim daawaynta nooca II ee sonkorowga.Laba astaamood oo farmaajo ah oo ka dhigaya linagliptin marka laga reebo kuwa kale ee DPP-4 inhibitors waa inay leedahay astaan-farmakokinetic aan toos ahayn oo aan marka hore meesha laga saarin nidaamka kelyaha.Linagliptin (maalintii hal mar) waxaa ansixiyay FDA US 2dii Maajo 2011 daawaynta nooca II ee sonkorowga.Waxaa suuq geynaya Boehringer Ingelheim iyo Lilly.Linagliptin, oo lagu iibiyo magaca sumadda Tradjenta iyo kuwa kale.Waxa si wadajir ah loo isticmaalaa jimicsi iyo cunto.