Luliconazole CAS 187164-19-8 Nadiifinta ≥99.0% HPLC Warshada API Tayada Sare
Bixinta Luliconazole iyo Dhexdhexaadiyeyaasha la xidhiidha
Luliconazole CAS 187164-19-8
(1-Imidazolyl)acetonitrile CAS 98873-55-3
(S)-2,4-Dichloro-α-(Chloromethyl) benzyl Alcohol CAS 126534-31-4
| Magaca Kiimikada | Luliconazole |
| La mid ah | (2E) -2- [(4R) -4- (2,4-Dichlorophenyl) -1,3-dithiolan-2-ylidene]-2- (1H-imidazol-1-yl) acetonitrile;NND 502 |
| Lambarka CAS | 187164-19-8 |
| Lambarka CAT | RF-API110 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C14H9Cl2N3S2 |
| Miisaanka Molecular | 354.27 |
| Meesha dhalaalaysa | 150.0 ilaa 154.0 ℃ |
| Wareeg gaar ah [a]20/D | -48.0° ilaa -53.0° (C=1, DMF) |
| Solubility | Aan ku milmin Biyaha;Ku milmay acetone;In yar oo ku milma Methanol |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Ka-caddan ilaa budada Jaallaha ah ee Crystalline |
| Aqoonsiga IR | Xajmiga infrared ee muunadku waa inuu u dhigmaa heerka tixraaca |
| Aqoonsiga HPLC | Waqtiga haynta ee ugu sarreysa xalka muunada waa inuu u dhigmaa midka xalka caadiga ah sida lagu helay tijaabada |
| Khasaare xagga qalajinta | ≤0.50% |
| Hadhaaga dabka | ≤0.20% |
| Biraha culus (Pb) | ≤20pm |
| Walxaha laxidhiidha | |
| Xumaan Shaqsiyeed Kasta | ≤0.20% |
| Wadarta wasakhda | ≤0.50% |
| Xalalka Haraaga ah | |
| Methanol | ≤3000pm |
| Acetonitrile | ≤410pm |
| Dichloromethane | ≤600pm |
| N-Hexane | ≤290pm |
| Ethyl acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720pm |
| Methyl tert-Butyl Ether | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| Triethylamine | ≤320pm |
| Dimethyl Sulfoxide | ≤5000ppm |
| Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) (oo ku salaysan qalalan) |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyeyaasha Daawooyinka |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Luliconazole (CAS: 187164-19-8) waa antifungal antifungal imidazole antibiyootiko ah oo leh firfircooni ballaadhan oo xoog leh.Luliconazole waa nooc ka mid ah analoogga lanoconazole.Waxay faragelin kartaa isku dhafka gidaarka unugyada fangas iyo korriinka fangas iyadoo hoos u dhigaysa heerarka ergosterol iyadoo la joojinayo dhaqdhaqaaqa demethylase lanosterol.Marka laga soo tago in loo isticmaalo daawaynta cagaha orodka, cuncunka jock-ka iyo gooryaanka, waxa sidoo kale loo sameeyay daawaynta onychomycosis ( fungus ciddiyaha) oo hadda waxa ay gashay marxaladda kiliinikada ee III.Alaabtan waxaa markii hore soo saartay Shirkadda sunta cayayaanka ee Japan (NihonNohyaku Co., Ltd.).Bishii Noofambar 2013, FDA waxay ansixisay 1% kareem luliconazole si loogu soo galo suuqa si loogu daaweeyo cagaha ciyaaraha fudud, cuncunka cuncunka iyo gooryaanka magaca ganacsiga ee Luzu oo markii ugu horeysay soo galay suuqa Waqooyiga Ameerika.Horraantii Abriil 2005, luliconazole ayaa loo oggolaaday inay suuqa Japan ku gasho magaca ganacsiga Lulicon.Bishii Janaayo 2010 iyo Juun 2012, waxaa loo oggolaaday suuq-geynta Hindiya iyo Shiinaha, siday u kala horreeyaan.
