Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity>99.0% (HPLC) Nintedanib Esylate Dhexdhexaad Warshada Sawirka

Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity>99.0% (HPLC) Nintedanib Esylate Warshada Dhexe

Sharaxaad Gaaban:

Magaca Kiimikada: Methyl 2-Oxoindoline-6-Carboxylate

CAS: 14192-26-8

Daahirsanaanta:>99.0% (HPLC)

Muuqashada: Jaalle fudud ilaa budada Brown

Dhexdhexaadiyaha Nintedanib Esylate (CAS: 656247-18-6) ee daawaynta kansarka sambabada unugyada aan yarayn iyo fibrosis sambabada idiopathic (IPF)

Tayada Sare, Wax Soo Saarka Ganacsiga

E-Mail: alvin@ruifuchem.com

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Sharaxaad:

Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha iyo soo saaraha ugu horreeya ee Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) oo leh tayo sare leh, wax soo saar ganacsi.

Guryaha Kiimikada:

Magaca Kiimikada	Methyl 2-Oxoindoline-6-Carboxylate
La mid ah	2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate
Lambarka CAS	14192-26-8
Lambarka CAT	RF-PI1524
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C10H9NO3
Miisaanka Molecular	191.19
Meesha dhalaalaysa	184.0 ~ 190.0 ℃
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Jaalle fudud ilaa budada Brown
1 H NMR Spectrum	Waafaqsan Qaab-dhismeedka
Daahirnimada / Habka Falanqaynta	>99.0% (HPLC)
Khasaare xagga qalajinta	<1.00%
Wadarta wasakhda	<1.00%
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadiyaha Nintedanib Esylate (CAS: 656247-18-6)

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Jidka synthetic

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.

Faa'iidooyinka

FAQ:

Codsiga:

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) waa dhexdhexaad ah oo loo isticmaalo diyaarinta Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate waa awood xoog leh, oo afka laga qaato angiokinase inhibitor saddex-geesoodka ah oo uu sameeyay Boehringer Ingelheim kaas oo bartilmaameedsada waddooyinka proangiogenic iyo pro-fibrotic ee ay dhexdhexaadiyaan soo-dhoweeyaha xuubka korriinka endothelial, soo-dhoweeyaha koritaanka fibroblast iyo qoysaska soo-dhowaynta koritaanka platelet, iyo sidoo kale Src iyo Flt-3 kinases.Nintedanib Esylate waxaa loo ansixiyay daawaynta idiopathic pulmonary fibrosis (IPF), xaalad kaas oo sambabada ay noqdaan kuwo si tartiib tartiib ah u nabarra waqti ka dib, US FDA bishii Oktoobar 2014 iyo EMA bishii Janaayo 2015. FDA waxay siisay nintedanib esylate fast-track , dib u eegista mudnaanta leh, alaabta agoonta, iyo magacaabista horumarka.Waxa kale oo ay ansixisay EMA bishii Noofambar 2014 si loogu daweeyo kansarka sanbabada unug yar oo ay weheliso docetaxel ka dib daaweynta kiimikaad ee safka hore.