Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 daahirnimo>98.0% (HPLC) Lenvatinib Mesylate Warshada Dhexe
Qalabka Kiimikada ee Ruifu Lenvatinib Mesylate Dhexdhexaadiyeyaasha oo leh nadiif sare
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Magaca Kiimikada | Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
La mid ah | Lenvatinib wasakhnimo 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;Lenvaint-D |
Lambarka CAS | 205448-66-4 |
Lambarka CAT | RF-PI1970 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C12H10ClNO3 |
Miisaanka Molecular | 251.67 |
Barta Karsan | 377.4± 37.0 ℃ |
Cufnaanta | 1.320± 0.06 g/cm3 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Ka-bax-caddan ilaa budada adag ee jaalaha ah |
1 H NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) |
Khasaare xagga qalajinta | <1.00% |
Wadarta wasakhda | <2.00% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaad/Iyo Xumaannimada Lenvatinib Mesylate (CAS: 857890-39-2) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) waa dhexe ee Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib waa dawada kansarka qanjirka tayroodh ay samaysay Eisai Corporation of Japan (Code: E7080), oo iska leh xannibaadaha afka ee tyrosine kinase (RTK) oo xakameyn kara dhaqdhaqaaqa kinase ee xuubka kobaca endothelial ee xididdada R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Lenvatinib waxa kale oo uu joojin karaa ku lug lahaanshaha RTK-yada kale ee angiogenesis-ka pathological, koritaanka burooyinka, iyo horumarka kansarka marka laga reebo hawlahooda gacanta ee caadiga ah oo ay ku jiraan fayraska koritaanka fibroblast (FGF) receptors FGFR1, 2, 3, iyo 4;Soo-dhoweeyaha korriinka ee platelet-derived (PDGFR [alpha]), KIT, iyo RET.[Tilmaanta]: Lenvatinib waxay ku habboon tahay daaweynta bukaannada kansarka tayroodh ee soo noqnoqda deegaanka ama nooca metastasis, nooca horumarka iyo shucaaca iodine-refractory nooc kala duwan.