Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Tayada Sare
Sahayda Ganacsi ee Molnupiravir iyo Dhexdhexaadiyayaasha la xidhiidha Tayada Sare leh
Uridine CAS 58-96-8
Cytidine CAS 65-46-3
Molnupiravir N-1 CAS 2346620-55-9
Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Magaca Kiimikada | Molnupiravir N-1 |
| La mid ah | ((3aR,4R,6R,6aR) -6-((E) -4- (hydroxyimino) -2-oxo-3,4-dihydropyrimidin-1 (2H) -yl) -2,2-dimethyltetrahydrofuro[3, 4-d [1,3] dioxol-4-yl) methyl isobutyrate;Dhexdhexaadiyaha Molnupiravir;Molnupiravir Dimethyl Dioxol wasakh;Molnupiravir wasakh 11 |
| Lambarka CAS | 2346620-55-9 |
| Lambarka CAT | RF-PI310 |
| Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
| Qaanuunka molecular | C16H23N3O7 |
| Miisaanka Molecular | 369.37 |
| Solubility | Ku milmay DMSO |
| Cufnaanta | 1.51± 0.1 g/cm3 |
| Heerkulka dhoofinta | Ambient |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ilaa budo cad-cad |
| Khasaare xagga qalajinta | ≤1.0% |
| Hadhaaga dabka | ≤0.20% |
| Xumaanta Keliya | ≤0.50% |
| Wadarta wasakhda | ≤2.0% |
| Biraha culus | ≤20pm |
| daahirnimo | ≥98.0% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadka Molnupiravir (CAS 2349386-89-4) COVID-19 |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Molnupiravir N-1 (CAS 2346620-55-9), waa dhexdhexaadka Molnupiravir (CAS 2349386-89-4) ee daaweynta COVID-19.Molnupiravir (EIDD-2801) waa qaab noole afka laga heli karo oo ah analoog ribonucleoside ah oo aad u xoog badan oo joojisa ku-noqoshada fayraska RNA ee badan oo ay ku jiraan SARS-CoV-2, wakiilka sababa COVID-19.EIDD-2801 (7 mg/kg; po; laba jeer maalintii 3.5 maalmood) waxay si weyn u yaraynaysaa culayska fayraska ee daadsan iyo muddada qandhada.Molnupiravir (EIDD-2801) ayaa si hufan loogu nadiifiyaa vivo ka dib nuugista, taasoo keentay in la ogaado NHC oo kaliya oo bilaash ah oo ku jira balaasmaha.EIDD-2801 waxay si adag u yaraynaysaa MERS-CoV titer-ka faafa, fayraska RNA, iyo cudur-sidaha iyada oo hoos timaada xaaladaha ka hortagga iyo daaweynta hore labadaba.Molnupiravir (EIDD-2801, MK-4482) waa soosaar afka laga heli karo oo ka mid ah daawada ribonucleoside analooga β-d-N4-hydroxycytidine (NHC; EIDD-1931) oo leh hawlo fayrus ballaaran oo ka dhan ah SARS-CoV-2, MERS-CoV, SARS-CoV, iyo wakiilka keena COVID-19.
