N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Purity>99.0% (HPLC) Afatinib Dimaleate Warshada Dhexdhexaadinta Sawirka

N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Purity>99.0% (HPLC) Afatinib Dimaleate Warshada Dhexe

Sharaxaad Gaaban:

Magaca Kiimikada: N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine

CAS: 162012-67-1

Daahirsanaanta:>99.0% (HPLC)

Muuqashada: Jaal fudud ilaa budada jaalaha ah

Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

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Sharaxaad:

Dhexdhexaadiyaha Keenida Kiimikada Ruifu ee Afatinib
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Guryaha Kiimikada:

Magaca Kiimikada	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine
La mid ah	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitro-4-Quinazolinamine;(3-Chloro-4-Fluorophenyl) (7-Fluoro-6-Nitroquinazolin-4-yl) amin;4-(3-Chloro-4-Fluoroanilino)-7-Fluoro-6-Nitroquinazoline;Afatiib Dhexdhexaad A
Lambarka CAS	162012-67-1
Lambarka CAT	RF-PI2026
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C14H7ClF2N4O2
Miisaanka Molecular	336.68
Dareenka	Xasaasiyadda hawada, Xasaasida kulaylka
Meesha dhalaalaysa	242.0 ~ 244.0 ℃
Barta Karsan	489℃
Cufnaanta	1.616
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Jaalle fudud ilaa budada jaalaha ah
Daahirnimada / Habka Falanqaynta	>99.0% (HPLC)
Khasaare xagga qalajinta	<0.50%
Hadhaaga dabka	<0.20%
Walxaha laxidhiidha
Xumaanta Shaqsiga ah	<0.50%
Wadarta wasakhda	<1.00%
Biraha culus	≤20pm
Infrared Spectrum	Waafaqsan Qaab-dhismeedka
Proton NMR Spectrum	Waafaqsan Qaab-dhismeedka
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

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FAQ:

Codsiga:

N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine (CAS: 162012-67-1) waa dhex dhexaad u ah isku dhafka Afatinib Dimaleate (CAS: 850140-73-7) .Afatinib Dimaleate waa nooc cusbo ah oo Afatiib ah.Afatinib waa jiilka labaad, afka laga maamulo, horjooge aan laga noqon karin ee qoyska ErbB ee kinases tyrosine.Farsamaynta ActionAfatinib waxay hoos u dhigtaa calaamadaynta ErbB iyada oo si wadajir ah ugu xidhaysa xayndaabka kinase ee soo-dhowaynta koritaanka epidermal (EGFR), soo-dhoweeyaha koritaanka epidermal ee bini'aadamka (HER) 2 iyo HER4, taasoo keentay xannibaad aan la bedeli karin ee tyrosine kinase autophosphorylation;waxay sidoo kale joojisaa transphosphorylation ee HER3.Afatinib waxaa loo oggolaaday sidii monotherapy ahaan daaweynta EGFR tyrosine kinase inhibitor (TKI) - dadka qaangaarka ah ee aan caqli-gal ahayn ee leh maxalli horumarsan ama QeexidChEBI: Milix lab ah oo la helay iyadoo la isku daray afatinib iyo laba molar oo u dhiganta maleic acid.Loo isticmaalo daawaynta safka kowaad ee bukaanada qaba kansarka sambabada unug yar-yar.