N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Qiimaynta 98.5 ~ 101.0% Warshada Tayada Sare
Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) oo leh tayo sare leh.Kiimikada Ruifu waxay keentaa asiidhyo amino oo taxane ah iyo soosaarayaal.Sababtoo ah tayada alaabtayada wanaagsan, qiimaha macquulka ah, waxaan helnay sumcad wanaagsan iyo sidoo kale kalsoonida macaamiishayada gudaha iyo dibaddaba.Waxaan bixin karnaa COA, gaarsiinta adduunka oo dhan, tiro yar iyo tiro badan oo la heli karo.Haddii aad xiisaynayso N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | N-Acetyl-L-Cysteine |
| La mid ah | Ac-Cys-OH;Acetylcysteine;NAC;LNAC;N-Acetylcysteine;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine |
| Heerka Saamiyada | Kaydka dhexdiisa, Awoodda Wax-soo-saarka 50 Tan bishii |
| Lambarka CAS | 616-91-1 |
| Qaanuunka molecular | C5H9NO3S |
| Miisaanka Molecular | 163.19 |
| Meesha dhalaalaysa | 106.0 ~ 108.0 ℃ |
| Xasaasi ah | Xasaasiyadda hawada |
| Biyuhu milmayn | Ku milmay Biyaha, Ku dhawaad Hufnaan |
| Solubility | Ku milmay Ethanol, Methanol, Khamriga.Dhaqan ahaan Aan lagu milmi karin Ether |
| Heerkulka Kaydinta | Lagu xidhay qalalan, ku kaydi heerkulka qolka |
| COA & MSDS | La heli karo |
| Kala soocidda | Amino Acids & Derivatives |
| Summada | Kiimikada Ruifu |
| Bayaanka Khatarta | 36/37/38 - Cuncun xagga indhaha, habka neefsashada iyo maqaarka. |
| Bayaanada Badbaadada | S22 - Ha neefsan boorka.S24/25 - Iska ilaali taabashada maqaarka iyo indhaha. |
| WGK Germany | 3 |
| RTECS | HA1660000 |
| F | 10-23 |
| TSCA | Haa |
| Koodhka HS | 2922491990 |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Crystals cad ama budada crystalline;Dhadhanka Asiidh adag | waafaqsan |
| Aqoonsiga | Nuugista Infrared Spectrum | waafaqsan |
| Wareeg gaar ah [α]20/D | +21.3° ilaa +27.0° (C=5 oo ku jirta cusbada Fosphate Buffered) | +23.5° |
| Xaaladda Xalka ( Gudbinta) | Cad iyo Midab la'aan ≥98.0% | 99.0% |
| Chloride (Cl) | ≤0.040% | <0.040% |
| Sulfate (SO4) | ≤0.030% | <0.030% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Birta (Fe) | ≤20pm | <20ppm |
| Biraha culus (Pb) | ≤10pm | <10pm |
| Zinc (Zn) | ≤10pm | <10pm |
| Arsenic (As2O3) | ≤1.0pm | <1.0pm |
| Walxaha laxidhiidha | (HPLC Habka) | |
| L-Cystin | ≤0.50% | waafaqsan |
| L-Cysteine | ≤0.50% | waafaqsan |
| N,N'-Diacetyl-L-Cystin | ≤0.50% | waafaqsan |
| N,S-Diacetyl-L-Cysteine | ≤0.50% | waafaqsan |
| Midba midka kale Xumaan | ≤0.50% | waafaqsan |
| Wadarta wasakhda | ≤0.50% | waafaqsan |
| Khasaare xagga qalajinta | ≤0.50% | 0.20% |
| Hadhaaga dabka (Sulfated) | ≤0.20% | 0.05% |
| Qiimayn | 98.5 ilaa 101.0% (oo ku salaysan qalalan) | 99.90% |
| Qiimaha pH | 2.0 ilaa 2.8 (1.0g ee 100ml ee H2O) | 2.5 |
| Sumowga biochemical | Gudub | Gudub |
| Walxaha Dabiiciga ah ee Kacsan | Gudub | Gudub |
| Ogaanshaha Endonuclease | ≤0.1 EU/g | <0.1 EU/g |
| Gabagabo | Alaabtan iyadoo la raacayo shuruudaha kormeerka ee heerka AJI97 | |
| Isticmaalka Muhiimka ah | Amino Acids;Cuntada lagu daro;Dhexdhexaadiyeyaasha Daawooyinka | |
Xidhmada: Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha daboolan bakhaar qabow, engegan oo hawo leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) AJI97 Habka Imtixaanka
N-Acetyl-L-Cysteine, marka la qalajiyo, ka kooban wax aan ka yarayn 98.5 boqolkiiba oo aan ka badnayn 101.0 boqolkiiba N-Acetyl-L-Cysteine (C5H9NO3S).
Sharaxaad: Kiristaalo cad ama budo crystalline, dhadhan asiidh adag.
Si xor ah ugu milmay biyaha, ku milma ethanol, ficil ahaan aan lagu milmi karin ether.
Solubility (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Aqoonsiga: Is barbar dhig nooca nuugista infrared-ka ee muunada iyo kan heerka caadiga ah ee habka saxanka bromide ee potassium.
Wareegga Gaarka ah [α]20/D: Muunad qallalan, C=8, xalinta fosfatada
Xaaladda Xalka ( Gudbinta): 0.5g gudaha 10ml ee H2O, spectrophotometer, 430nm, dhumucda unugga 10mm.
Biraha culus (Pb): 2.0g, (1), tixraac: 2.0ml ee Pb Std.(0.01mg/ml)
Zinc (Zn): Habka nuugista atomiga
Walxaha laxidhiidha: Habka HPLC
Khasaare ku saabsan qalajinta: meel faaruq ah, at 70 ℃ 4 saacadood
Hadhaaga dabka (Sulfated): AJI Test 13
Qiimaynta: Muunad qallalan, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g gudaha 100ml ee H2O
Xadka kaydinta lagu taliyay iyo xaalada: weelasha cidhiidhiga ah ee la ilaaliyo ee heerkulka qolka la kantaroolay (1 sano).
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Habka Imtixaanka USP35
Qeexitaan
Acetylcysteine ayaa ka kooban NLT 98.0% iyo NMT 102.0% L-threonine (C5H9NO3S), oo lagu xisaabiyo sal qallalan.
AQOONSIGA
A. NUUXDA INFRAREED <197K>
ASSAY
HABKA
Marxaladda wareegta: 6.8 g/L ee fosfatta potassium monobasic.Ku hagaaji phosphoric acid una beddel pH 3.0.
Sodium metabisulfite xal: 0.5 mg/mL of sodium metabisulfite biyo, si cusub loo diyaariyey
Xalka caadiga ah ee gudaha: 5 mg/mL ee USP L-Phenylalanine RS gudaha Sodium metabisulfite
Xalka saamiga caadiga ah: 10 mg/mL oo ah USP acetylcysteine RS gudaha Sodium metabisulfite
Xalka caadiga ah: 0.5 mg/mL oo ah USP Acetylcysteine RS iyo 0.25 mg/mL ee USP L-Phenylalanine RS ee Sodium metabisulfite xalinta saamiga caadiga ah iyo xalalka gudaha gudaha
Tusaalaha xalalka kaydka: 10 mg/mL of Acetylcysteine ee xalalka Sodium metabisulfite
Xalka muunada: 0.5 mg/mL of Acetylcysteine iyo 0.25mg/mL of USP L-Phenylalanine RS in Sodium metabisulfite xalinta saamiga saamiga iyo xal gudaha gudaha
Nidaamka Chromatographic
(Fiiri Chromatography <621>, Habboonaanta Nidaamka.)
Habka: LC
Baaraha: UV 214 nm
Tiirka: 3.9-mm × 30-cm;xirxiran L1
Heerka socodka: 1.5 ml/min
Cabbirka duritaanka: 5µL
Ku habboonaanta nidaamka
[Xusuusin-Xilliyada xajinta qaraabo ee acetylcysteine iyo L-phenylalanine waa qiyaastii 0.5 iyo 1.0, siday u kala horreeyaan.]
Shuruudaha ku habboonaanta
Xallinta: NLT 6 inta u dhaxaysa acetylcysteine iyo L-phenylalanine
Qiyaasta heerka qaraabada: NMT 2.0%
Falanqaynta
Tusaalooyinka: Xalka caadiga ah iyo xalalka muunada
Xisaabi boqolkiiba acetylcysteine (C5H9NO3S) ee qaybta Acetylcysteine ee la qaatay:
Natiijadu = (RU/RS) × (CS/CU) × 100
RU = saamiga jawaabta ugu sarreysa ee acetylcysteine ilaa L-phenylalanine oo ka yimid xalka Tusaalaha
RS = saamiga jawaabta ugu sarreysa ee acetylcysteine ilaa L-phenylalanine oo ka yimid xalalka caadiga ah
CS = fiirsashada USP acetylcysteine RS ee xalka caadiga ah (mg/mL)
CU = fiirsashada acetylcysteine ee xalka muunada (mg/mL)
Shuruudaha aqbalaadda: 98.0% -102.0% ee salka qallalan
XANUUNKA
Hadhaaga dabka <281>: NMT 0.5%
BIRTA CULUS, Habka II <231>
[CAUTION-Daryeel jimicsi sababtoo ah qarax ayaa dhici kara.]
Falanqaynta: Habka hoos u dhaca, ku qoyso muunada 2 mL oo nitric acid ah, oo u soco sida lagu farayo diyaarinta Imtixaanka.
Shuruudaha aqbalaadda: NMT 10 ppm
IMTIXAANO GAAR AH
Wareegga indhaha, wareeg gaar ah <781S>
Bakhaar: Isku qas 29.5 mL oo ah 1 N sodium hydroxide, 50 ml oo ah 1 M fosfateta potassium monobasic, iyo biyo ku filan si aad u samayso 100 ml.Isku hagaaji pH ee 7.0 ± 0.1 adigoo ku daraya wax ka badan labada xal, sida loo baahdo.
Xalka muunada: 25-mL weel mug leh, ku qas 1.25 g iyo 1 mL oo ah xalinta disodium edetate (1 100kii), ku dar 7.5mL oo ah sodium hydroxide (1 ee 25), ku dar si aad u milmaan.Ku milmi kaydka ilaa mugga.
Shuruudaha aqbalaadda: +21° ilaa +27°
pH <791>: 2.0-2.8 ee xalka (1 in 100)
LUUMKA QALABKA <731>: Ku qalaji muunad cadaadis dhan 50 mm oo mercury ah 70° 4 saac: waxa ay luminaysaa NMT 1.0% miisaankeeda.
SHURUUD DHEERAAD AH
BAAKAYNTA IYO KAYDINTA: Ku kaydi weelal cidhiidhi ah, oo ku kaydi heerkulka qolka kontaroolan.
HEERARKA Tixraaca USP <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Shaqada & Codsiga N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) budada
1. N-Acetyl-L-Cysteine, oo sidoo kale loo yaqaan N-Acetylcysteine ama Acetylcysteine (NAC), waa daawo dawooyin ah iyo kaab nafaqo oo loo isticmaalo ugu horreyn sida wakiilka mucolytic iyo maaraynta paracetamol (acetaminophen) xad-dhaaf ah.Isticmaalka kale waxaa ka mid ah buuxinta sulfate ee xaaladaha, sida ootiisamka, halkaas oo cysteine-ka iyo asiidhyada amino acids sulfur ee la xidhiidha laga yaabo inay yaraato.
2. N-Acetyl-L-Cysteine waa nooc ka mid ah cysteine-ka halkaasoo koox acetyl ah ay ku xiran tahay atamka nitrogen-ka.Xaruntan waxaa loo iibiyaa sidii kabitaan cunto ah oo inta badan sheeganaysa saamaynta ilaalinta beerka iyo antioxidant.Waxa loo isticmaalaa sida daawaynta qufaca sababta oo ah waxa ay jebisaa xidhmooyinka disulfide ee xabka ku jira oo ay dareerisaa, taas oo sahlaysa in la qufaco.Sidoo kale waa falkan jabinta curaarta disulfide ka ka dhigaysa mid faa'iido u leh khafiifinta xabka aan caadiga ahayn ee dhumucdiisuna tahay bukaannada cystic iyo fibrosis sambabada.
3. Acetylcysteine waa wakiil mucolytic ah oo leh saameyn xoog leh oo mucolytic ah.Kooxda sulfhydryl ee ku jirta molecule-ku waxay jebin karaan isku-xidhka disulfide-ka ee silsiladda glycoprotein polypeptide ee ku jirta xaakada, si ay u yareeyaan viscosity ee xaakada, iyo samaynta xaakada dareere ah oo fudud in qufaca.Alaabtani waxay sidoo kale jebin kartaa fiilooyinka DNA-da ee xaakada purulent, sidaa daraadeed kaliya ma milmi karto xaako cad oo dhegdheg leh, laakiin sidoo kale ma diri karto xaakada purulent.Bukaanka kuwaas oo filashadooda guud ay tahay mid aan waxtar lahayn, alaabtani waxay weli noqon kartaa mid waxtar leh.
4. Waxaa dawo ahaan loo isticmaalaa si ay u milmaan xaakada.Waxa loo isticmaalaa cilmi-baadhista biochemical iyo dawo ahaan ka-hortagga xaakada iyo sumowga acetaminophen.Reagent biochemical, daawo, alaabtan waxaa loo isticmaalaa sidii expectorant, ayaa sheegay in xaakadu ay fududahay in la nadiifiyo.
5. Waxyeelooyinka caadiga ah waxaa ka mid ah lallabbo iyo matag marka afka laga qaato. Maqaarku wuxuu noqon karaa mid guduudan oo cuncuna labada noocba.Nooc aan difaac lahayn oo anaphylaxis ah ayaa sidoo kale dhici karta.Waxay u muuqataa inay ammaan tahay uurka.Qiyaasta xad dhaafka ah ee paracetamol, waxay u shaqeysaa iyadoo kordhinaysa heerka glutathione, oo ah antioxidant ka takhalusi karta sunta burburka sunta ah ee paracetamol.Marka la nuugo, waxay u shaqeysaa sidii xuubka xuubka isagoo yareynaya dhumucda xabka.
6. Acetylcysteine ayaa markii hore la shatiyeeyay 1960-kii waxayna soo gashay adeegsigeeda caafimaadka 1968. Waxay ku jirtaa liiska dawooyinka muhiimka ah ee Ururka Caafimaadka Adduunka, kaas oo taxaya daawooyinka ugu badbaado iyo waxtarka badan ee looga baahan yahay nidaamka caafimaadka.Waxaa loo heli karaa daawo guud waana mid aan qaali ahayn.
7. N-Acetyl-L-Cysteine waa nooca acetylated ee L-cysteine kaas oo si hufan loo nuugo loona isticmaalo.Sidoo kale waa antioxidant-ka ka caawiya fayraska.N-Acetyl-l-Cysteine waxa loo isticmaalay difaac beerka ah iyo in la jebiyo xababka sambabada iyo bronki.
8. N-Acetyl-L-Cysteine waxay kor u qaadi kartaa heerarka glutathione ee unugyada.
9. N-Acetyl-L-Cysteine waa amino acid shuruudaysan lagama maarmaanka u ah, mid ka mid ah saddexda amino acids sulfur-ka kooban, kuwa kale waa taurine (oo laga soo saari karo L-cysteine ) iyo L-methionine oo L-cysteine ka soo saari karo. in lagu soo saaro jidhka iyada oo loo marayo habraac dhowr tallaabo ah.
10. N-Acetyl-L-Cysteine waxay u dhaqmi kartaa sida antioxidant-ka, waxay ka hortagi kartaa cudurrada beerka, waxayna kaa caawin kartaa inay dhumucdo dhexroorka shakhsi ahaaneed ee timaha jira haddii si joogto ah loo qaato.
11. Codsiga goobaha caafimaadka Sida wakiilka habdhiska neefsiga, waxa loo isticmaali karaa daawo ahaan dirida durbaanka xaakada.waxay daweyn kartaa boronkiitada.Intaa waxaa dheer, N-Acetyl-L-Cysteine loo isticmaali karaa ka-hortagga-ka-hortagga marka acetaminophen sumowga.
12. Codsiga goobaha qurxinta N-Acetyl-L-Cysteine waxay saameyn weyn ku leeyihiin nadiifinta xaglaha xorta ah ee ogsijiinta iyo oksijiinta kale waxayna hoos u dhigtaa habka gabowga, waxay sidoo kale carqaladeyn kartaa wax soo saarka melanin, waxayna caawineysaa in la baabi'iyo xuubka maqaarka.
13. Codsiga quudinta xoolaha N-Acetyl-L-Cysteine waxaa loo isticmaali karaa quudin ahaan.
14. Waxyaabaha la isku qurxiyo oo inta badan loo isticmaalo biyaha quruxda, dareeraha perm, kareemka daryeelka maqaarka ee aan cadceedu.Leh shaqo uu kaga hortago gabowga noolaha.N-Acetyl-l-Cysteine waxay si wax ku ool ah uga hortagi kartaa una daweyn kartaa dhaawaca shucaaca.N-acetyl Cysteine wuxuu ka saari karaa maqaarka melanin laftiisa, beddelka dabeecadda maqaarka laftiisa, maqaarku wuxuu noqdaa caddaan dabiici ah.
15. Cuntada lagu daro.Loo isticmaalo rootiga, si kor loogu qaado sameynta gluten iyo kor u qaadista halsano, caaryada, ka hortagga gabowga.Waxaa loo isticmaalaa cabitaannada dabiiciga ah si looga hortago fitamiin C-ga inuu oksaydheeyo iyo si looga hortago in casiirka uu isu beddelo bunni.
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