N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Assay 99.0~101.0 Warshada
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha iyo soo saaraha ugu horreeya ee N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) oo leh tayo sare leh.Kiimikada Ruifu waxay keentaa asiidhyo amino oo taxane ah iyo soosaarayaal.Alaab tayo sare leh, qiimo macquul ah, aad u fiican oo degdeg ah adeegga iibka ka dib ayaa ah ballanqaadyada Kiimikada Ruifu ee macaamiisha.Waxaan bixin karnaa COA, gaarsiinta adduunka oo dhan, tiro yar iyo tiro badan oo la heli karo.Haddii aad xiisaynayso N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | N-Acetyl-L-Tyrosine |
| La mid ah | Ac-Tyr-OH;Ac-L-Tyr-OH;N-Ac-L-Tyr;NALT;Ac-Tyrosine;Acetyltyrosine;N-Acetyltyrosine;Acetyl-Laevo-Tyrosine;LN-Acetyltyrosine;(2S)-2-(Acetylamino)-3- (4-Hydroxyphenyl) Propanoate;(S)-2-Acetamido-3- (4-Hydroxyphenyl) Propanoic Acid;N-Acetyl-(S)-2-Amino-3- (4-Hydroxyphenyl) Propionic Acid;(2S)-2-(Acetylamino)-3-(4-Hydroxyphenyl) Propanoic Acid |
| Heerka Saamiyada | Kaydka dhexdiisa, Awoodda Wax-soo-saarka 30 Tan sannadkii |
| Lambarka CAS | 537-55-3 |
| Qaanuunka molecular | C11H13NO4 |
| Miisaanka Molecular | 223.23 g/mol |
| Meesha dhalaalaysa | 150.0 ilaa 154.0 ℃ |
| Cufnaanta | 1.304 |
| Biyuhu milmayn | Ku milmay Biyaha, Ku dhawaad Hufnaan |
| Heerkulka Kaydinta | Lagu xidhay qalalan, ku kaydi heerkulka qolka |
| COA & MSDS | La heli karo |
| Kala soocidda | Amino Acids & Derivatives |
| Summada | Kiimikada Ruifu |
| Xeerarka Khatarta | Xi - xanaaq | F | 10 |
| Bayaanka Khatarta | 41-36/37/38 | TSCA | Haa |
| Bayaanada Badbaadada | 26-39-36 | Koodhka HS | 2922491990 |
| WGK Germany | 3 |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Crystals cad ama budada crystalline | waafaqsan |
| Aqoonsiga | Nuugista Infrared Spectrum | waafaqsan |
| Wareeg gaar ah [α]20/D | +46.5° ilaa +49.0°(C=2 gudaha H2O) | +47.2° |
| Xaaladda Xalka ( Gudbinta) | ≥96.0% | 98.3% |
| Chloride (Cl) | ≤0.020% | <0.020% |
| Sulfate (SO4) | ≤0.020% | <0.020% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Birta (Fe) | ≤30pm | <30ppm |
| Biraha culus (Pb) | ≤10pm | <10pm |
| Arsenic (As2O3) | ≤2.0pm | <2.0pm |
| Tirosine | ≤1.00% | waafaqsan |
| Khasaare xagga qalajinta | ≤0.50% | 0.25% |
| Hadhaaga dabka (Sulfated) | ≤0.10% | 0.07% |
| Qiimayn | 99.0 ilaa 101.0% | 99.5% |
| Qiimaha pH | 2.0 ilaa 3.0 | 2.3 |
| Gabagabo | Buuxiyay heerka AJI97, USP35 | |
| Isticmaalka Muhiimka ah | Kaabayaasha Cuntada;Cuntada lagu daro;Dhexdhexaadiyeyaasha Daawooyinka | |
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Habka Imtixaanka AJI97
N-Acetyl-L-Tyrosine, marka la qalajiyo, waxay ka kooban tahay wax aan ka yarayn 99.0 boqolkiiba oo aan ka badnayn 101.0 boqolkiiba N-Acetyl-L-Tyrosine (C11H13NO4).
Sharaxaad: Kiristaalo cad ama budo crystalline, dhadhan asiidh adag
Si xor ah ugu milmay biyaha.
Solubility (H2O, g/100g): 17.5 (20℃), 72.4 (40℃), 158 (60℃)
Aqoonsiga: Is barbar dhig nooca nuugista infrared-ka ee muunada iyo kan heerka caadiga ah ee habka saxanka bromide ee potassium.
Wareegga Gaarka ah [α]20/D: Muunad qallalan, C=4, H2O
Xaaladda Xalka ( Gudbinta): 0.5g gudaha 10ml ee H2O, spectrophotometer, 430nm, dhumucda unugga 10mm.
Chloride (Cl): 0.7g, A-1, tixraac: 0.40ml ee 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), tixraac: 0.50ml ee 0.005mol/L H2SO4
Birta (Fe): 0.5g, tixraac: 1.5ml ee Iron Std.(0.01mg/ml)
Biraha culus (Pb): 2.0g, (3), tixraac: 2.0ml ee Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), tixraac: 2.0ml of As2O3 Std.
Luminta qallajinta: at 105 ℃ 3 saacadood
Hadhaaga dabka (Sulfated): AJI Test 13
Qiimaynta: Muunad qallalan, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: chromatography dareere ah.Xaaladda hawlgalka: Baaraha: Sawir-qaade nuugista UV (214nm);Tiirka: ODS, 4.6mm x 150mm;Heerkulka Tiirka: Heerkulka qolka.Heerka socodka: 1ml/min;Marxaladda wareegta: 0.04mol/L xalinta fosfatka monopotassium (pH 4.35): Methanol (193:3)
pH: 1.25g gudaha 50ml ee H2O
Xadka kaydinta lagu taliyay iyo xaalada: weelasha adag ee la ilaaliyo ee heerkulka qolka la kantaroolay (2 sano).
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Habka Imtixaanka USP35
Qeexitaan
N-Acetyltyrosine wuxuu ka kooban yahay NLT 98.5% iyo NMT 101.0% ee C11H13NO4, sida N-Acetyl-L-Tyrosine, oo lagu xisaabiyo sal qallalan.
AQOONSIGA
A. NUUXDA INFRAREED <197K>
B. ROOTICAL OPTICAL, Wareegid Gaar ah <781S>
Tusaalaha xalalka: 10 mg/mL
Shuruudaha aqbalaadda: NLT +46.0° iyo NMT +49.0°, oo lagu go'aamiyey 20°
C. Qiimaha RF ee meesha ugu muhiimsan ee xalka Tusaalaha ee tijaabada ee wasakhaynta Dabiiciga ah waxay u dhigantaa kan xalalka caadiga ah 1.
ASSAY
HABKA
Xalka Tusaalaha: Ku milmi qiyaastii 180 mg ee N-Acetyltyrosine, oo lagu miisaamay, 50 mL oo biyo la'aan ah kaarboon laba ogsaydh.
Nidaamka Titrimetric
(Fiiri Titrimetry <541>)
Habka: Titration toos ah
Titrant: 0.1 N sodium hydroxide VS
Ogaanshaha barta dhamaadka: Potentiometric
U dhigma: ML kasta oo ah 0.1 N sodium hydroxide VS waxay u dhigantaa 22.32 mg ee C11H13NO4.
XANUUNKA
wasakhda aan noolaha ahayn
DABINTA HAA DHACAY <281>: NMT 0.1%
Kloride iyo sulfate, Chloride <221> NMT 200 ppm.Qayb 0.7-g ah ma muujiso koloriin ka badan oo u dhiganta 0.40 mL oo ah 0.01 N hydrochloric acid.
Kloride iyo sulfate, Sulfate <221> NMT 200 ppm.Qaybta 1.2-g waxay muujinaysaa wax ka badan sulfate oo u dhiganta 0.25 mL oo ah 0.020 N sulfuric acid.
IRON <241>: NMT 20ppm
Biraha culus, Habka I <231>: NMT 10ppm
Waxyeellada dabiiciga ah
HABKA
Adsorbent: 0.25-mm lakabka silica jel chromatographic ah
Xalka saamiga caadiga ah 1: 8 mg/mL ee USP N-Acetyl-L-tyrosine RS ee isku dhafka biyaha, glacial acetic acid, iyo khamriga (3:3:94)
Xalka caadiga ah 1: Ku qas xal saamiga caadiga ah 1 aalkolo si aad u hesho xal isagoo la og yahay 0.4 mg/mL
Xalka caadiga ah 2: 0.8 mg/mL ee USP L-Tyrosine RS ayaa lagu milmay isku dar ah acetic acid iyo biyo (1: 1), oo lagu qasi jiray aalkolo
Xalka muunada: Ku wareeji 0.8 g N-Acetyltyrosine ilaa 10-mL weel mug leh, ku milmi 6 mL oo ah isku dhafka glacial acetic acid iyo biyo (1: 1), oo ku mil khamriga ilaa mugga.
Codsiga mugga: 5µL
Horumarinta habka dareeraha: Isku dhafka ammonia iyo 2-propanol (3:7)
Daawada reagent: Ku mil 0.2 g oo ninhydrin ah 100 mL oo isku dhafka ah ee butanol iyo 2 N acetic acid (95:5).
Ku habboonaanta nidaamka
Shuruudaha ku habboonaanta: chromatogram-ka xalka ku habboonaanta nidaamka wuxuu muujinayaa laba baro oo si cad u kala soocan.
Falanqaynta: U wad sida lagu faray Chromatography <621> Chromatography-ka khafiifka ah.Ka dib markaad hawo-qaboojiso saxanka, ku celi habka horumarinta.Ka dib marka hawada la qalajiyo mar labaad, ku buufi reagent buufin, oo kulayl inta u dhaxaysa 100 ° iyo 105 ° ilaa 15 daqiiqo.
Shuruudaha aqbalaadda: Meel kasta oo labaad ee xalka Tusaalaha kama weyna ama kama xoog badna meesha ugu muhiimsan ee Halbeegga xalinta1, marka laga reebo barta u dhiganta tyrosine, taas oo aan ka weynayn ama ka xoog badnayn meesha ugu muhiimsan ee xalalka 2.
Nijaasaha shaqsiga ah: NMT 0.5%
Xadka tyrosine: NMT 1.0%
IMTIXAANO GAAR AH
LOSSON QALABKA <731>: Ku qalaji muunad 105 ℃ 3 saac: waxay luminaysaa NMT 0.1% miisaankeeda.
SHURUUD DHEERAAD AH
Baakadaha iyo Kaydinta: Ku kaydi weelasha si fiican u xidhan, oo ku kaydi heerkulka qolka kontaroolan.
HEERARKA Tixraaca USP <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS
Xidhmada: Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha daboolan bakhaar qabow, engegan oo hawo leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.Ka fogow walxaha oksaydhka ee xooggan.
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Shaqada & Codsiga N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) budada
1. N-Acetyl-L-Tyrosine waa acetyl ka soo jeeda amino acid, L-tyrosine.Waxay si xor ah ugu milmay biyaha marka la barbar dhigo L-tyrosine waxaana badanaa loo isticmaalaa kabka nafaqada waalidka.N-Acetyl-L-Tyrosine, qaab xasiloon oo aad u milmay oo tyrosine ah, ayaa lagu daray qaar ka mid ah hababka amino acid-ka ee waalidnimada ganacsiga ee hadda jira sida TrophAmine iyo Aminosyn-II.
2. N-Acetyl-L-Tyrosine waxay ku lug leedahay wax soo saarka catecholamine.Waxaa loo isticmaali karaa sidii qayb ka mid ah warbaahinta dhaqanka unugga ee bioomanufacture-ka ganacsiga ee borotiinnada dib-u-daweynta iyo unugyada difaaca jirka ee monoclonal.
3. N-Acetyl-L-Tyrosine waa amino acids lagama maarmaanka u ah, kaas oo ah nooc ka mid ah nafaqooyinka muhiimka u ah dheef-shiid kiimikaadka aadanaha iyo xayawaanka, korriinka iyo korriinka ayaa door muhiim ah ka ciyaara, waxaa si ballaaran loogu isticmaali karaa cuntada, daawooyinka iwm.
4. N-Acetyl-L-Tyrosine waxa ay qayb lama huraan ah ka ciyaartaa isku dhafka dopamine iyo hormoonnada kale ee jidhkaaga.Waxay kor u qaadi kartaa heerarka neurotransmitters dopamine, norepinephrine iyo epinephrine.Waxay ka caawisaa inay taageerto heerarka sare ee diiradda iyo shaqada garashada.Waxay kordhin kartaa xusuusta shaqada iyo dareenka fayoobida.
5. N-Acetyl-L-Tyrosine waxaa laga beddelay Tyrosine caadiga ah sababtoo ah waxay ka kooban tahay ku darida acetic acid.Tani waxay dhab ahaantii ka caawisaa inay kordhiso bioavailability ka xarunta si ay si fiican ugu nuugo dhiigga si toos ah.
6. N-Acetyl-L-Tyrosine waa nooc aad u bioavailable ah oo L-Tyrosine ah oo loogu talagalay daaweynta hore ee dabiiciga ah ee niyadda hoose N-Acetyl-L-Tyrosine waxaa loo isticmaali karaa qiyaaso ka hooseeya L-Tyrosine.L-Tyrosine-ka caadiga ah aad ayuu u xasilan yahay oo aan lagu milmi karin biyaha, taas oo keeni karta in ay yaraato helitaanka noolaha.
7. N-Acetyl-L-Tyrosine waxa ay xoojisaa milanka iyo xasiloonida taas oo ka dhigaysa mid si degdeg ah u nuugaya oo noolaha laga heli karo oo ah amino acid L-Tyrosine kaas oo aan u nuglaadan soo saarista kaadida.
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