Octreotide Acetate CAS 83150-76-9 Peptide Purity (HPLC) ≥98.0% API Tayada Sare
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee Octreotide Acetate (CAS: 83150-76-9) oo leh tayo sare.Kiimikada Ruifu waxay bixisaa taxane ah peptides GMP.Ruifu waxa uu bixin karaa keenista aduunka oo dhan, qiimo tartan ah, tiro yar iyo tiro badan oo la heli karo.Iibso Octreotide Acetate,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Octreotide acetate |
| La mid ah | SMS 201-995;Samilstin;Octreotide-LAR; |
| Tixraacyo | D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol |
| Dhoola cadeyn | [FCFWKTCT(Bundada Disulfide: Cys2-Cys7)] |
| Lambarka CAS | 83150-76-9 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Kiiloogaraam |
| Qaanuunka molecular | C49H66N10O10S2 |
| Miisaanka Molecular | 1019.24 |
| Meesha dhalaalaysa | > 140 ℃ (dac.) |
| Cufnaanta | 1.39±0.10 g/cm3 |
| Solubility | Ku milma Acid Acid, DMSO, iyo Methanol |
| Xasilooni | Hygroscopic |
| Heerkulka Kaydinta | Qabow & Meel Qalalan (2 ~ 8 ℃).Qaboojiyaha |
| Dukumeenti | COA, MS, HPLC, NMR, MSDS, iwm. |
| Qaybta | GMP Peptides |
| WGK Germany | 3 |
| Shuruudaha Rarida | Bacaha Barafka, Bacaha qallajiya |
| Summada | Kiimikada Ruifu |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Budada Cad | Budada Cad |
| Solubility | Ku milmay biyaha ama 1% acetic acid marka la uruuriyo ≥1mg/ml si loo siiyo xal aan midab lahayn | waafaqsan |
| Falanqaynta Amino Acid (Waxaa qoray HPLC) | Th: 0.7 ~ 1.1 | 0.9 |
| Cys: 1.0 ~ 2.2 | 1.9 | |
| Luska: 0.9 ~ 1.3 | 1.1 | |
| Phe: 1.8 ~ 2.2 | 1.9 | |
| Thr-OL: 0.6 ~ 1.3 | 0.9 | |
| Trp: 0.4 ~ 1.1 | 0.8 | |
| Nadiifinta Peptide (Waxaa leh HPLC) | ≥98.0% (oo ah isdhexgalka aaga) | 99.81% |
| Walxaha La Xiriira (Waxaa leh HPLC) | Wadarta wasakhda (%) ≤2.0% | 0.19% |
| Xumaanta Keliga ah ee ugu Weyn (%) ≤1.0% | 0.12% | |
| Waxyaabaha Acetate (HPLC) | 5.0 ~ 12.8% | 9.6% |
| Waxyaabaha Biyaha ka kooban (Karl Fischer) | ≤7.0% | 2.7% |
| Waxyaabaha ay ka kooban tahay TFA (Karl Fischer) | ≤0.25% | 0.13% |
| Wareegga indhaha ee gaarka ah | -45.0°～-55.0° (C=0.5, 95% HAC) | -51.5° |
| Qiimayn | 95.0 ~ 105.0% (Anhydrous, Acid Asiidh bilaash ah) | 99.0% |
| Asal ahaan Alaabta | Synthetic | |
| Fiiro gaar ah | Kaliya Cilmi-baaris, Maaha Isticmaalka Aadanaha | |
| Gabagabo | Alaabta waa la tijaabiyay oo waafaqay qeexitaannada | |
| Isticmaalka | GMP Peptides;Walaxda Farmashiyeedka Firfircoon (API) | |
Xidhmada:Fiilada caaga ah (oo loogu talagalay xirmooyinka peptide) ama dhalo dhalada ah, tirada sida waafaqsan shuruudaha tafatirka macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xidhan meel qabow oo engegan (2 ~ 8℃) bakhaar ka fog walxaha aan ku haboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Gaarsiiya adduunka oo dhan FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Octreotide Acetate (Sandostatin) waa analoogga peptide synthetic ee hoormoonka somatostatin, waa analoogga somatostatin oo muddo dheer shaqeynayey oo loogu talagalay xakameynta calaamadaha ee burooyinka acromegaly iyo gastroenteropancreatic.Isticmaalka kale ee suurtagalka ah ee la baarayo waxaa ka mid ah sonkorowga, psoriasis iyo cudurka Alzheimers.Octreotide Acetate (Sandostatin) waa analoogga peptide synthetic ee hormoonka somatostatin.Ficilkeeda waxaa ka mid ah joojinta dheecaanka pituitary ee hoormoonka korriinka iyo xakameynta dheecaanka unugyada islet-ka ee ganaca ee insulin iyo glucagon.Si ka duwan somatostatin, oo leh nus-nolosha balasmaha ee dhowr daqiiqo, Octreotide waxay leedahay baabi'inta balaasmaha nuska nolosha 1 ilaa 2 saacadood.Soo saarista dawada ayaa ugu horraysa kelyaha.Octreotide waxay yaraynaysaa dhaqdhaqaaqa caloosha iyo mindhicirka waxayna joojisaa foosha xameetida.
Daawooyinka Peptide Novartis Sandostatin (Octreotide Acetate), waa somatostatin octapeptide dabiiciga ah ee dabiiciga ah, waxay haysaa saameyn farmashiyeed oo la mid ah somatostatin, saameyntuna waa mid dheer.Tilmaamaha Octreotide Acetate waxaa ka mid ah acromegaly;Yaraynta calaamadaha iyo calaamadaha la xidhiidha shaqada gastroenteropancreatic endocrine neoplasia;Iyo waxtarka Burooyinka Carcinoid ee soo bandhigaya cudurka kansarka, burooyinka VIP, iyo burooyinka glucagon.Intaa waxaa dheer, Octreotide Acetate ee gastrinomas / Zollinger-Ellison syndrome (badanaa marka lagu daro proton pump inhibitors ama H2 receptor blockers), Insulinomas (kahortagga kahortagga hypoglycemia iyo ilaalinta sonkorta dhiigga caadiga ah), heerka wax ku oolka ah ee hoormoonka koritaanka ee sii daaya buro factor waa qiyaastii 50%.
Octreotide Acetate waa caymiska caafimaadka qaranka ee fasalka B, kaas oo ah octapeptide dabiiciga ah ee dabiiciga ah ee somatostatin, marka la barbar dhigo somatostatin dabiiciga ah, nolosha nuska ah ee somatostatin ayaa si cad u sii dheeraysa waxayna leedahay saameyn isku mid ah oo dawooyin ah, oo ay ku jiraan joojinta shaqada hoormoonka koritaanka, ka hortagga. ee acid gastric, enzyme ganaca, glucagon iyo dheecaanka insulin, iyo hoos u dhigista socodka dhiigga visceral, hoos u dhac dhaqdhaqaaqa caloosha.Marka la barbar dhigo somatostatin hooyo, octreotide waxa uu leeyahay nus-nolosho dheer, waxa uu aad uga door bidaa xakamaynta dheecaanka hoormoonka korriinka marka loo eego joojinta dheecaanka insulin, mana keeno dib u soo noqoshada hormoonka.1, Xakamaynta qaliinka ama daaweynta shucaaca si ku filan uma xakameyn karto cudurka bukaanka qaba calaamadaha acromegaly waxayna yareeyaan hormoonka koritaanka bukaanka (GH) insulin-sida koritaanka factor -1 (1GF-1) heerarka plasma.Sandostatin waxa kale oo loo isticmaali karaa in lagu daweeyo bukaanada qaba acromegaly kuwaas oo aan awoodin ama aan doonaynin in lagu sameeyo qalliin, ama lagu daweeyo bukaanada qaba acromegaly kuwaas oo aan weli helin daaweynta shucaaca.2. Yaraynta calaamadaha la xidhiidha burooyinka qanjidhada 'endocrine' ee shaqada ee gastroenteropancreatic (GEP) sida burooyinka kansarka leh ee carcinoid syndrome.Sandostatin ma aha dawada ka hortagga kansarka mana daaweyso bukaankan.3, Kahortagga dhibaatooyinka qalliinka ganaca kadib.4, Bukaannada beerka ee beerka leh ee leh dhiig-baxa caloosha-sophageal variceal ee ay keento daaweynta degdega ah, hemostasis iyo ka hortagga dib-u-baxa, Sandostatin waa in lagu daraa endoscopic sclerotherapy iyo daaweyn kale oo gaar ah.
Dhibaatooyinka soo raaca ee alaabtani waa Xanuunka caloosha, kala-baxa caloosha, Shuban, steatorrhea;Samaynta dhagaxa xameetida;Dulqaadka gulukoosku waxa laga yaabaa inuu yaraado ama ka sii daro marxaladda hore ee daaweynta, ka dibna waa la hagaajin karaa;Codsiga muddada-dheer ee aan lahayn wax-soo-saarka antibody-ka, ma jirin dib-u-celin cad ama fal-celin xun markii daawada la joojiyay ama si degdeg ah loo dhimay.2 ~ 8 deg C kaydinta muddada-dheer.
