Olmesartan Medoxomil CAS 144689-63-4 daahirnimo>99.5% (HPLC) Warshada API
Keenista Kiimikada Ruifu Olmesartan Medoxomil Dhexdhexaadiyaha Tayada Sare leh:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Tril Olmesartan Ethyl Ester CAS 144690-33-5
Triyl Olmesartan Acid CAS 761404-85-7
N2-Tryl Olmesartan Acid CAS 752179-89-8
Tril Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Magaca Kiimikada | Olmesartan Medoxomil |
La mid ah | 4- (1-Hydroxy-1-methylethyl) -2-propyl-1-[2'- (2H-tetazol-5-yl) [1,1'-biphenyl] -4-yl] methyl]-1H- imidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;CS-866 |
Lambarka CAS | 144689-63-4 |
Lambarka CAT | RF-PI1730 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C29H30N6O6 |
Miisaanka Molecular | 558.60 |
Meesha dhalaalaysa | 180 ℃ (diseembar) |
Biyuhu milmayn | Aan ku milmin Biyaha;Wax yar oo ku milma DMSO |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa Ku dhawaad Caddaan budada Cyrstalline |
Aqoonsiga | IR, HPLC, UV: Waa in uu waafaqsan yahay heerka tixraaca |
Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC oo ku salaysan Anhydrous iyo Aasaaska Ka Xorta ah) |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.10% |
Walxaha laxidhiidha | |
Olmesartan RRT 0.2 | <0.50% |
Isku dhafka Olmesartan Medoxoil ee La Xiriira A. RRT 0.7 | <0.20% |
Xumaanta Olefinic RRT 1.6 | <0.50% |
N-Alkyl wasakhnimada RRT 3.4 | <0.10% |
Wax kasta oo wasakh kale ah | <0.10% |
Wadarta wasakhda | <0.50% |
Biraha culus (sida Pb) | <10pm |
pH ee Xalka (2%, W/V) | 4.5 ilaa 6.5 |
Heerka Imtixaanka | Heerka Ganacsiga;Heerka USP |
Isticmaalka | API |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) waa awood iyo xulashada angiotensin II nooca 1 (AT (1)) antagonist receptor leh IC50 of 66.2 μM., loo isticmaalo daaweynta dhiig karka.Loo isticmaalo sidii anti-hypertensive.Olmesartan wuxuu u shaqeeyaa isagoo xannibaya ku-xidhka angiotensin II ee soo-dhoweeyayaasha AT1 ee muruqa xididdada dhiigga.Isagoo xannibaya isku-xidhka halkii uu ka samaysan lahaa angiotensin II, Olmesartan wuxuu joojiyaa falcelinta sharciyeed ee xun ee dheecaanka renin.Olmesartan Medoxomil waa daawo ka-hortag ah oo laga dejiyay dheef-shiid kiimikaad firfircoon, olmesartan.Olmesartan Medoxomil waxaa laga bilaabay Maraykanka sida Benicar, oo ah daawaynta afka laga qaato ee dhiig-karka.