Oseltamivir Phosphate (Tamiflu) CAS 204255-11-8 API Tayada Sare
U keeni Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Oseltamivir Phosphate
CAS: 204255-11-8
API Tayada Sare, Wax soo saarka Ganacsiga
| Magaca Kiimikada | Oseltamivir Phosphate |
| La mid ah | Tamiflu |
| Lambarka CAS | 204255-11-8 |
| Lambarka CAT | RF-API87 |
| Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
| Qaanuunka molecular | C16H31N2O8P |
| Miisaanka Molecular | 410.4 |
| Meesha dhalaalaysa | 196.0 ilaa 198.0 ℃ |
| Heerkulka Kaydinta | 2-8℃ |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystalline ee Caddaan iyo Off-White |
| Aqoonsiga | IR, HPLC |
| Qiimayn | 98.0% ~ 101.5% (HPLC ku salaysan anhydrous) |
| Waxyaalaha biyaha (waxaa qoray KF) | ≤0.50% |
| Wareegga indhaha ee gaarka ah | -30.7° ilaa -32.6° (C=1 gudaha H2O) |
| Walxaha laxidhiidha 1 | (HPLC) |
| Oseltamivir Acid | ≤0.30% |
| Oseltamivir Pheol | ≤0.10% |
| Najaasad kasta oo aan la cayimin | ≤0.10% |
| Wadarta wasakhda | ≤0.40% |
| Walxaha laxidhiidha 2 | Isku dhafka Oseltamivir A ≤0.01% (HPLC-MS) |
| Walxaha laxidhiidha 3 | Tributyl Phosphine ≤0.10% (GC) |
| Biraha culus | ≤10pm |
| Hadhaaga dabka | ≤0.20% |
| Biraha culus | ≤20pm |
| Nolosha shelf | 24 bilood |
| Heerka Imtixaanka | Heerka Ganacsiga;USPharmacopoeia (USP) Heerka |
| Isticmaalka | API, Kahortagaha afka ah ee fayraska hargabka neuraminidase |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Oseltamivir Phosphate waa ka hortag afka ah oo firfircoon ee fayraska hargabka neuraminidase;In vivo oo loo beddelo metabolite aashitada firfircoon.Daawooyinka fayraska ka hortaga.Waa shey cilmi baaris oo COVID19 la xiriira.Oseltamivir phosphate waa nooc ka mid ah dawooyinka ka hortagga hargabka, oo hoos yimaada magaca ganacsiga Tamiflu.Oseltamivir waxaa laga bilaabay Maraykanka iyo Switzerland si loogu daweeyo caabuqyada hargabka ee dhammaan fayrasyada nooca caadiga ah.Oseltamivir wuxuu u soo baxay sidii mid ka mid ah labadii hormood ee neuraminidase inhibitors si ay u gaaraan suuqa.Oseltamivir waxaa loo ansixiyay in uu yahay ka hortagga neuraminidase-ka ugu horreeya ee afka laga qaato ee loo isticmaalo ka hortagga hargabka A iyo fayrasyada B.Daawada waxaa loogu talagalay daawaynta jirro degdeg ah oo aan dhib lahayn oo uu keeno caabuqa hargabka.
