Palbociclib CAS 571190-30-2 daahirnimo>99.5% (HPLC) Warshada API
Qalabka Kiimikada ee Ruifu Palbociclib Dhexdhexaadiyaha La Xiriira:
Palbociclib CAS 571190-30-2
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Magaca Kiimikada | Palbociclib |
La mid ah | PD-0332991;Otava-Bb 1115529;Ibraansi |
Lambarka CAS | 571190-30-2 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C24H29N7O2 |
Miisaanka Molecular | 447.54 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama Off-Cad |
1H NMR Spectrum | Waafaqsan Qaab-dhismeedka |
HPLC | Waafaqsan Qaab-dhismeedka |
Walxaha laxidhiidha | |
Xumaanta Shaqsiga ah | <0.50% |
Wadarta wasakhda | <1.00% |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.10% |
Biraha culus | <10pm |
Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API, ee Daaweynta Kansarka Naasaha |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Palbociclib (CAS: 571190-30-2) waa ka hortag afka laga heli karo cyclin-dependent kinase (CDK) oo leh firfircoonida antineoplastic.Palbociclib waxay si xushmad leh u joojisaa kinase 4 (CDK4) iyo 6 (CDK6), taas oo ka hortagaysa retinoblastoma (Rb) fosforyaalka borotiinka horaantii wajiga G1 taasoo horseedaysa xiritaanka wareegga unugyada.Tani waxay yaraynaysaa taranka DNA waxayna yaraynaysaa kororka unugyada burooyinka.Palbociclib waa wakiilka koowaad ee fasalka cusub ee daroogada ee kinase inhibitors-ku-tiirsan.Saamayntan ayaa xaddidaysa kororka unugyada (koritaanka unugyada iyo kala qaybinta).Waxa loo isticmaalaa sidii wakiilka antineoplastic ee kansarka naasaha ee horumarsan ama metastatic.