Palbociclib Dhexdhexaad CAS 1016636-76-2 daahirnimo>99.0% (HPLC) Warshada
Qalabka Kiimikada ee Ruifu Palbociclib Dhexdhexaadiyaha La Xiriira:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -hal CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-hal CAS 1013916-37-4
Magaca Kiimikada | 6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -hal |
La mid ah | Palbociclib-Pb3 |
Lambarka CAS | 1016636-76-2 |
Lambarka CAT | RF-PI1849 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C13H13BrClN3O |
Miisaanka Molecular | 342.63 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa qafiif ah budada jaalaha ah |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
Walxaha laxidhiidha | <1.00% |
Khasaare xagga qalajinta | <0.50% |
Biyaha (KF) | <0.50% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexe ee Palbociclib (CAS: 571190-30-2) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H) -hal (CAS: 1016636-76-2) waa dhex dhexaad u ah Palbociclib (CAS: 571190- 30-2).Palbociclib waa daawo loogu talagalay daawaynta ER-positive iyo HER2-negative kansarka naasaha ee la sameeyay.Palbociclib waa horjooge door ah oo ka mid ah kinase-ku-tiirsanaanta cyclin CDK4 iyo CDK6.Febraayo 3, 2015, US FDA waxay ansixisay Pfizer's Palbociclib (magaca ganacsiga: Ibrance) ee daawaynta kansarka naasaha ee horumarsan/mestastatic ee haweenka postmenopausal.Palbociclib waa horjoogaha ugu horreeya ee CDK4/6 si loo helo oggolaanshaha FDA.