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Palonosetron Hydrochloride CAS 135729-62-3 daahirnimo>99.0% (HPLC) (T) Sawirka Warshada API
  • Palonosetron Hydrochloride CAS 135729-62-3 daahirnimo>99.0% (HPLC) (T) API Warshada

Palonosetron Hydrochloride CAS 135729-62-3 daahirnimo>99.0% (HPLC) (T) API Warshada

Sharaxaad Gaaban:

Magaca Kiimikada: Palonosetron Hydrochloride

CAS: 135729-62-3

Muuqashada: Caddaan ama Off-White Crystalline Powder

Daahirsanaanta:>99.0% (HPLC) (T)

Palonosetron Hydrochloride waa mid aad u xoog badan, door ah oo afka firfircoon 5-HT3 antagonist receptor antagonist loo isticmaalo ka hortagga iyo daaweynta kiimoterabi-ku-lallabbo iyo matag (CINV).Antiemetic

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com


Faahfaahinta Alaabta

Alaabooyinka La Xiriira

Tags Product

Sharaxaad:

Iibka Ganacsiga Palonosetron Hydrochloride iyo Dhexdhexaadiyayaasha La Xiriira:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Guryaha Kiimikada:

Magaca Kiimikada Palonosetron Hydrochloride
La mid ah Palonosetron HCl;(S, S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-Hexahydro-1H-Benzo[de] isoquinolin-1-hal Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2] oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de]isoquinolin-1-hal Hydrochloride ;Aloxi;Onicit
Lambarka CAS 135729-62-3
Lambarka CAT RF-API03
Heerka Saamiyada Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular C19H24N2O·HCl
Miisaanka Molecular 332.87
Shuruudda Laga Fogaado Xasaasida kulaylka
Meesha dhalaalaysa 307 ℃ (dac.)
Ku milmay biyaha Si Buuxda Ugu Milmayn Biyaha
Solubility Wax yar oo ku milma Ethanol
Heerkulka dhoofinta Heerkulka deegaanka
COA & MSDS La heli karo
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Caddaan ama Banaan-cad budada Crystalline
Palonosetron Hydrochloride >99.0% (HPLC) (T)
Wareeg gaar ah [α]20/D -98.0°～-104.0°
Aqoonsiga Ku dar BiI7K4,Samee Roobka Jaallaha ah ee Orange
Aqoonsiga TLC Waafaqsan Walaxda Tixraaca
Aqoonsiga IR Waafaqsan Heerka IR
Aqoonsiga Aqoonsiga sida Chloride
Solubility Si xor ah ugu milmay biyaha, si yar ugu milmay Methanol, wax yar ku milmi kara ethanol, aan lagu milmi karin acetone
Cadaynta iyo Midabka Xalka Max.Jaallaha No. 2 Xalka Midabka Caadiga ah
pH Vaule 4.5 ~ 6.5 (10mg/ml)
Suurtagalnimada La Xiriira
Isku dhafka A (MAYA) <0.10%
Isku dhafka B ee la xidhiidha (Ene-NO) <0.10%
Isku dhafka C (S,R) ee la xidhiidha <0.10%
Isku dhafka D (R,S) <0.50%
Palonosetron Enantiomer <0.10%
Isku dhafka E (3-Ene) <0.50%
Xumaanta Keliya Aan La cayimin <0.10%
Xalalka Haraaga ah
Ethanol <3000pm
Tetrahydrofuran <5000pm
DMF <880ppm
Hexane caadiga ah <290pm
Methyl Khamriga <3000pm
Isopropanol <5000pm
Methylbenzene <890ppm
Biyo <0.30%
Hadhaaga dabka <0.20%
Khasaare xagga qalajinta <1.00%
Biraha culus <10pm
Heerka Imtixaanka USPharmacopoeia (USP);Yurub Pharmacopoeia (EP)
Isticmaalka Palonosetron Hydrochloride API;5-HT3 Ka soo horjeeda;CINV

Xidhmada & Kaydinta:

Xidhmada: Dhalo, Durbaan kartoon, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

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Codsiga:

Palonosetron Hydrochloride (CAS: 135729-62-3) waa daawo si loo joojiyo lallabada iyo matagga, taas oo ah nooc cusub oo si heer sare ah loo xushay, oo aad u sarreeya 5-HT3 antagonist oo xannibi kara matagga reflex center peripheral neurons presynaptic 5-HT.Farxadda qaabilaadda waxay si toos ah u saamaysaa habka dhexe ee neerfayaasha ee 5-HT.Farxadda soo-dhoweynta soo-dhoweynta ee ay keento doorka dareemaha afferent ee vagal ka dib aagga, xannibaadda dareemaha xididdada xuubka ee mindhicirka, ka hortagga calaamadaha 5-HT.Aagga kicinta ee qaboojiyaha ayaa yarayn kara dhacdooyinka lallabbo iyo matag.Xarunta dhexe ee daaweynta kiimoterabiga emetogenic ee ba'an ee degdega ah waxay keentay lallabbo iyo matag daahsan.Sababtoo ah saameynteeda daaweynta sare, saameyn yar oo yar, nolosha nuska dheer (qiyaastii 40 saacadood), qiyaas yar, iyo wixii la mid ah, waxay soo jiidatay dareen badan.

Iyadoo 1,2,3,4-Tetrahydro-1-Naphthoic Acid sida walxaha bilawga ah, kala qaybsanaanta, amination, dhimista, wareegga, cusbada palonosetron hydrochloride granisetron.Daraasadaha caafimaadku waxay muujiyeen in palonosetron loo isticmaali karo si badbaado leh corticosteroids, xanuunka xanuunka, antiemetics, antispasmodics iyo daawooyinka anticholinergic sida walxaha bilawga ah, kala qaybsanaanta, hoos u dhigista, wareegga wareegga, cusbada palonosetron hydrochloride granisetron.

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