Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Warshada
Qalabka Kiimikada ee Ruifu oo leh daahir sare
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
| Magaca Kiimikada | Paroxetine Hydrochloride Hemihydrate |
| La mid ah | (3S,4R)-(-) 3-[(1,3-Benzodioxol-5-yloxy) methyl] -4- (4-fluorophenyl) piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
| Lambarka CAS | 110429-35-1 |
| Lambarka CAT | RF-PI1946 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C19H20FNO3·HCl·1/2H2O |
| Miisaanka Molecular | 374.84 |
| Meesha dhalaalaysa | 140.0 ~ 143.0 ℃ |
| Wareeg gaar ah [α]20/D | -88.0° ilaa -92.0° (C=1, MeOH, Calcd.on anh.walax) |
| Solubility | Dhab ahaantii Biyo Aan Ku milmin;Aad u Soluble ee Dimethylformamide, Methanol;Ku milmay Ethanol |
| Summada | Kiimikada Ruifu |
| Nuxurka | Tilmaamaha | Natiijooyinka |
| Muuqashada | Caddaan ama ku dhawaad cad budada crystalline | U hoggaansamo |
| Aqoonsiga A | Muuqaalka nuugista infrared-ka waa in uu ahaado mid waafaqsan tixraaca tixraaca | U hoggaansamo |
| Aqoonsiga B | Meesha ugu sarreysa ee ugu weyn iyo waqtiga haynta ee xalka tijaabada waa in ay la socdaan xalka tixraaca | U hoggaansamo |
| Aqoonsiga C | Biyaha (waxaa qoray KF) | U hoggaansamo |
| Aqoonsiga D | Falcelinta Chlorides | U hoggaansamo |
| Xumaanta D | ≤0.20% | Maqan |
| Xumaanta G | ≤0.001% | |
| Walxaha laxidhiidha | wasakh A: ≤0.30% | 0.03% |
| Najaasaha Aan La Sheegin: Mid kasta oo wasakh ah, ≤0.10% | 0.06% | |
| Wadarta wasakhda: ≤0.50% | 0.10% | |
| Biraha culus | ≤0.002% | <0.002% |
| Biyaha (waxaa qoray KF) | 2.20% ~ 2.70% | 2.46% |
| Sulfated Ash | ≤0.10% | <0.10% |
| Qiimayn | 97.5% ~ 102.0% (Waxyaabaha Anhydrous) | 100.2% |
| Xalalka Haraaga ah | ||
| Methanol | ≤0.30% | 0.001% |
| Acetone | ≤0.50% | 0.001% |
| Isopropanol | ≤0.50% | 0.04% |
| Dichloromethane | ≤0.06% | Midna |
| Toluene | ≤0.089% | 0.003% |
| Gabagabo: Waafaqid EP7.0. | ||
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) waa mid ka mid ah kuwa ugu awoodda badan iyo xulashada serotonin reuptake inhibitors (SSRI);ka hortagga niyad-jabka.Waa derivative phenylpiperidine, waa ST (qaade-qaade serotonin/5-HT) aad u awood badan oo la xushay.Waxay u shaqeysaa iyada oo ku xiraysa ST (gaadiidka serotonin/SERT) xiriir sare leh (Ki = 05 nM).Daawooyinka niyad-jabka iyo anxiolytic ee vivo.Paroxetine hydrochloride waxaa loo isticmaali karaa in lagu daweeyo niyad-jabka, taas oo ah daawo cusub oo ka hortagta niyad-jabka.Waxa kale oo loo isticmaali karaa in lagu daweeyo weerarka argagaxa, khalkhalka guud ee walaaca, khalkhal bulsheed, xanuunka waswaaska ah (OCD), hurdo la'aanta, xanuunka caadada ka hor, biya baxa degdega ah iyo cuduro kale, oo leh saameyn daawasho wanaagsan iyo falcelin aan fiicneyn.daaw dhammaan noocyada niyad-jabka.Oo ay ku jiraan niyad-jabka walaaca leh iyo niyad-jabka falcelinta.Calaamadaha niyad-jabka ee caadiga ah: daal, hurdo la'aan, xiiso la'aan iyo raaxaysi hawl maalmeedka, luminta rabitaanka cuntada.Ka dib markii saameynta daawaynta lagu qanco, waxay ka hortagi kartaa soo noqoshada niyad-jabka.
