Pazopanib Hydrochloride CAS 635702-64-6 daahirnimo>99.0% (HPLC) Sawirka Warshada API

Pazopanib Hydrochloride CAS 635702-64-6 daahirnimo>99.0% (HPLC) Warshada API

Sharaxaad Gaaban:

Magaca Kiimikada: Pazopanib Hydrochloride

CAS: 635702-64-6

Muuqashada: Caddaan ilaa Wax yar oo Jaalle ah Budada

Daahirsanaanta:>99.0% (HPLC)

Tyrosine kinase receptor inhibitor ee daaweynta kansarka unugyada kelyaha ee horumarsan ama sarcoma unug jilicsan oo horumarsan

API Tayada Sare, Wax soo saarka Ganacsiga

Inquiry: alvin@ruifuchem.com

Email noogu soo dir

Faahfaahinta Alaabta

Alaabooyinka La Xiriira

Tags Product

Sharaxaad:

Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca Kiimikada: Pazopanib Hydrochloride
CAS: 635702-64-6
Tyrosine kinase reseptor inhibitor ee daaweynta kansarka unugyada kelyaha ee horumaray ama sarcoma unug jilicsan oo horumarsan kuwaas oo helay kiimoterabi hore.
API Tayada Sare, Wax soo saarka Ganacsiga

Guryaha Kiimikada:

Magaca Kiimikada	Pazopanib Hydrochloride
La mid ah	Pazopanib HCl;GW786034 HCl;Cod-bixiye;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide Hydrochloride
Lambarka CAS	635702-64-6
Lambarka CAT	RF-API93
Heerka Saamiyada	Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram
Qaanuunka molecular	C21H23N7O2S.ClH
Miisaanka Molecular	473.987
Solubility	DMSO
Meesha dhalaalaysa	300.0 ~ 304.0 ℃
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Jaalle Cadaan ilaa Inyar
Aqoonsiga	Noocyada nuugista infrared ee muunada tijaabada waxay la socotaa heerka caadiga ah
Hadhaaga dabka	≤0.50%
Xumaan Shaqsiyeed Kasta	≤0.30%
Wadarta wasakhda	≤1.50%
Biraha culus	≤10pm
Daahirnimada / Habka Falanqaynta	≥99.0% (HPLC)
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	API, Tyrosine kinase receptor inhibitor

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

FAQ:

Codsiga:

Pazopanib Hydrochloride (CAS 635702-64-6) waa Multi-tyrosine kinase inhibitor of vascular endothelial factor reseptor (VEGFR) -1, VEGFR-2, VEGFR-3, receptor factor koritaanka platelet-derived (PDGFR) -α iyo - β, fibroblast receptor factor (FGFR) -1 iyo -3, cytokine reseptor (Kit), interleukin-2 receptor-inducible T-cell kinase (Itk), borotiinka lymphocyte-gaar ah tyrosine kinase (Lck), iyo transmembrane glycoprotein tyrosine. kinase (cFms).In vitro, pazopanib waxay joojisay autophosphorylation-ka ligand ee VEGFR-2, Kit, iyo PDGFR-beta reseptors.In vivo, pazopanib waxay joojisay VEGF-ku-abuuray VEGFR-2 fosfooraska ee sambabada jiirka, angiogenesis ee qaabka jiirka, iyo koritaanka qaar ka mid ah burooyinka bini'aadamka xenografts ee jiirarka.Waxaa loo ansixiyay kansarka unugyada kelyaha ee Maamulka Cuntada iyo Dawooyinka ee Mareykanka 2009 waxaana lagu suuq geeyaa magaca ganacsiga Votrient ee soo saaraha daroogada, GlaxoSmithKline.Votrient waa kinase inhibitor loo tilmaamay daawaynta bukaanada qaba: 1) kansarka unugyada kelyaha oo horumaray.2) Sarcoma unug jilicsan oo horumarsan oo la siiyey daawaynta kiimiko hore.