Pirfenidone CAS 53179-13-8 daahirnimo ≥99.0% IPF
Bixinta Nadiif Sarreysa, Wax Soo Saarka Ganacsiga
Magaca Kiimikada: Pirfenidone
CAS: 53179-13-8
| Magaca Kiimikada | Pirfenidone |
| La mid ah | Perfenidone;5-Methyl-1-Phenylpyridine-2(1H) -hal;PFD;S-7701;AMR-69 |
| Lambarka CAS | 53179-13-8 |
| Lambarka CAT | RF-API108 |
| Heerka Saamiyada | In Stock |
| Qaanuunka molecular | C12H11NO |
| Miisaanka Molecular | 185.22 |
| Meesha dhalaalaysa | 96.0 ilaa 97.0 ℃ |
| Solubility | Ku milmay DMSO |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ilaa iftiin jaale ah budada crystalline |
| Aqoonsiga | IR |
| daahirnimo | ≥99.0% |
| Khasaare xagga qalajinta | ≤0.50% |
| Sulfated Ash | ≤0.20% |
| Xumaanta Keliya | ≤0.50% |
| Wadarta wasakhda | ≤1.0% |
| Biraha culus | ≤20pm |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API, Idiopathic Pulmonary Fibrosis (IPF) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Pirfenidone (CAS: 53179-13-8) waxay ku jirtaa koox dawooyin ah oo loo yaqaan wakiilada antifibrotic.Pirfenidone waxay muujisay waxqabadyo xaalado fibrotic oo badan, oo ay ku jiraan kuwa sambabada, kelyaha iyo beerka.Waxay saamaysaa habka difaaca jidhkaaga waxayna yaraynaysaa cadadka fibrosis (nabarrada) ee sambabada.Pirfenidone waa mid ka mid ah labada dawo ee laga ansixiyay Kanada si loogu daweeyo Idiopathic Pulmonary Fibrosis (IPF).Pirfenidone waa horjooge loogu talagalay soosaarka TGF-β iyo TGF-β waxay kicisay wax soo saarka kolajka, waxay yaraynaysaa wax soo saarka TNF-α iyo IL-1β, sidoo kale waxay leedahay sifooyinka anti-fibrotic iyo anti-bararka.Waxaa markii ugu horreysay lagu ansixiyay Japan si loogu daweeyo bukaannada qaba fibrosis sambabada idiopathic ka dib tijaabooyin caafimaad, oo hoos yimaada magaca ganacsiga ee Pirespa by Shionogi, 2008. Waxaa loo oggolaaday isticmaalka Midowga Yurub ee 2011, Kanada ee 2012, iyo in Mareykanka bishii Oktoobar 2014.
