Pregabalin CAS 148553-50-8 daahirnimo>99.0% (HPLC) API Antiepileptic

Sharaxaad Gaaban:

Magaca Kiimikada: Pregabalin

CAS: 148553-50-8

Muuqashada: Caddaan ilaa-cad-cad budada crystalline

Nadiifinta:> 99.0% (HPLC oo ku saleysan qalalan)

Jiilka Labaad ee Dawooyinka Kahortagga Cudurrada (AED)

API Tayada Sare, Wax soo saarka Ganacsiga 

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Sharaxaad:

Soo-saare leh Nadiif Sarreysa iyo Wax soo saar Ganacsi
Magaca Kiimikada: PregabalinCAS: 148553-50-8
Pregabalin waa daawada suuxdinta jiilka labaad (AED)

Guryaha Kiimikada:

Magaca Kiimikada Pregabalin
La mid ah (S)-3-(Aminomethyl) -5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Lyrica
Lambarka CAS 148553-50-8
Lambarka CAT RF-API57
Heerka Saamiyada Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular C8H17NO2
Miisaanka Molecular 159.23
Meesha dhalaalaysa 194.0-196.0 ℃
Ku milmay biyaha Dhaqan ahaan Aan Biyo Ku milmin
Solubility Wax yar oo ku milma Ethanol
Xaalada Maraakiibta Heerkulka deegaanka hoostiisa
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Budada Crystalline ee Caddaan iyo Off-White
Aqoonsiga IR: La mid ah Walxaha Tixraaca
Wareeg gaar ah +10.0°~+13.0° (C=1, Biyo)
Khasaare xagga qalajinta <0.50%
Sulfated Ash <0.10%
Walxaha laxidhiidha wasakh A <0.15%
Wasakhda Aan La Sheegin Ka Hor Pregabalin (tijaabi A) <0.10%
Waxyaalaha wasakhda ah ee aan la cayimin ee ka baxaya Pregabalin ka dib (tijaabada B) <0.10%
Wadarta imtixaanka A iyo B <0.50%
Daahirnimada By HPLC R-Isomer <0.15%
Biraha culus (sida Pb) <10pm
Chlorides (Cl) <0.05%
Xalalka Haraaga ah  
Khamriga isopropyl <5000pm
Ethyl acetate <5000pm
Tetrahydrofuran <250ppm
isopropyl Ether <500pm
Ethanol <1000pm
Daahirnimada / Habka Falanqaynta > 99.0% (HPLC ku salaysan qallalan)
Heerka Imtixaanka Heerka Ganacsiga
Isticmaalka Daawooyinka Antiepileptic API

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka & qoyaanka

Faa'iidooyinka:

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Codsiga:

Pregabalin waa dawada ka hortagga suuxdinta ee jiilka labaad (AED) oo loo yaqaan magaca astaanta leh ee Lyrica (Pfizer, Tadworth) ee UK iyo USA, oo leh qaab dhismeedka γ-amino butyric acid ee qaab dhismeedka molecular, kaas oo leh saameyn liddi ku ah, waana si guul leh ay u soo saartay shirkadda Pfizer ee loogu talagalay daawaynta xanuunka neuropathic durugsan, ama daaweynta qalalka qayb ahaan.Pregabalin waa Anticonvulsant iyo daawada suuxdinta loo isticmaalo in lagu daweeyo suuxdin, xanuunka neuropathic, fibromyalgia, iyo khalkhalka guud ee walaaca.Isticmaalkeeda suuxdintu waa sida daawaynta dheeriga ah ee suuxdinta qayb ahaan leh ama aan lahayn guud ahaan guud ee dadka waaweyn.Bishii Disembar 2008, Maamulka Cunnada iyo Dawooyinka ee Mareykanka (FDA) ayaa ansixiyay pregabalin (magaca ganacsiga "Lyrica") ee loogu talagalay daawaynta xanuunka neerfaha ee sokorowga (DPN) iyo neuralgia postherpetic (PHN) kuwaas oo ah labadaba xanuunka neuropathic ee ugu caansan.Pregabalin waxay leedahay tilmaam la ansixiyay waxaana si weyn loogu isticmaalaa daawaynta xanuunka welwelka guud.Dhawr aan kala sooc lahayn, laba-indho la'aan, tijaabooyin la xakameeyey ayaa lagu ogaaday in pregabalin ay tahay daaweyn wax ku ool ah oo loogu talagalay bukaanada qaba xanuunka guud ee walwalka iyo xanuunka welwelka bulshada.Qiyaasta titration daawaynta suuxdinta-isku-dhafan: 25 mg bd muddo 7 maalmood ah, in lagu kordhiyo 50 mg 7dii maalmoodba;dayactirka caadiga ah 300 mg maalin kasta, loo qaybiyaa 2 ama 3 qiyaasood (ugu badnaan 600 mg maalintii, loo qaybiyey 2 ama 3 qiyaasood).Ciladda walwalka guud: 150 mg maalin kasta, oo loo qaybiyo 2 ama 3 qiyaasood, 7 maalmood, in lagu kordhiyo 150 mg 7dii maalmoodba mar (ugu badnaan 600 mg maalin kasta, oo loo qaybiyo 2 ama 3 qiyaasood).Haddii la joojiyo pregabalin, waxaa lagu talinayaa in la duubo ugu yaraan 1 toddobaad si looga fogaado ka-bax degdeg ah.Digniin Bukaanada qaba xaalado laga yaabo inay soo dajiyaan encephalopathy.Bukaanka qaba wadne xanuun daran.

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