(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst CAS 112022-83-0 Nadiifnimada indhaha ≥98.0%

Qalabka wax-soo-saarka;Tayada Sare iyo Qiimaha Tartan

CBS Catalysts
(S)-(-)-2-Methyl-CBS-oxazaborolidine;(S)-Me-CBS Catalyst (ca. 1mol/L gudaha Toluene);CAS: 112022-81-8
(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst (ca. 1mol/L gudaha Toluene);CAS: 112022-83-0

CBS Catalyst
Kaaliyaha CBS ama Corey–Bakshi–Shibata katalistuhu waa kicinye asymmetric ah oo ka soo jeeda proline.Waxay ka heshaa adeegsiyo badan oo falcelinta dabiiciga ah sida dhimista CBS, falcelinta Diels-Alder iyo (3+2) cycloadditions.Proline, oo ah iskudhis si dabiici ah u soo baxa, waa diyaar oo raqiis ah.Waxa ay u gudbisaa stereocenter-keeda kicinta taas oo iyaduna awood u leh in ay u kaxayso falcelinta organic si xushmad leh mid ka mid ah laba enantiomers oo suurtagal ah.Xulashadan waxaa sabab u ah cidhiidhi adag oo ka jira xaaladda kala guurka ee u koraysa hal enantiomer laakiin aan ahayn kan kale.

Ka-hortagga CBS ee Yaraynta Asymmetric iyo Synthesis Asymmetric
CBS (Corey-Bakshi-Shibata) kicinta oxazaborolidine ayaa loo adeegsaday dhimista asymmetric ee ketones-ka prochiral.Codsiyada kale waxaa ka mid ah isku-darka enantioselective ee α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols, iyo alkolada propargyl.

(R)-(+)-2-Methyl-CBS-oxazaborolidine (ca. 1mol/L ee Toluene) CAS: 112022-83-0 waxa loo isticmaali karaa kicin ahaan hoos u dhigista borane asymmetric ee ketones perfluoroalkyl.Codsiyada kale waxaa ka mid ah isku-darka enantioselective ee α-hydroxy acids, α-amino acids, C2 ferrocenyl diols symmetrical, iyo alkolada propargyl.Waxa kale oo loo istcimaalaa dhimista desymmetry-ka taasoo keenaysa (S) -4-hydroxycyclohexenone.Waxay faa'iido u leedahay soo saarista motifs stereospecific sida α-hydroxy acids, α-amino acids, ferrocenyl diols symmetrical iyo alkolada propargyl.

(R)-(+)-2-Methyl-CBS-oxazaborolidine (ca. 1mol/L ee Toluene) CAS: 112022-83-0 waa kicinta organoboron oo loo isticmaalo isku-dhafka dabiiciga ah.Kiciyaan, oo ay soo saareen Itsuno iyo Elias James Corey, waxaa soo saaray kuleyliyaha (R)-(+)-2- (diphenylhydroxymethyl) pyrrolidine oo ay weheliso trimethylboroxine ama methylboronic acid.Waa qalab aad u fiican oo loogu talagalay isku dhafka khamriga ee saamiga enantiomeric sare.Guud ahaan, 2-10 mol% ka mid ah kicinta ayaa la isticmaalaa borane-tetrahydrofuran (THF), borane-dimethylsulfide, borane-N, N-diethylaniline, ama diborane sida isha borane.Dhimista Enantioselective iyadoo la adeegsanayo kiral oxazaborolidine kicinta ayaa loo adeegsaday isku dhafka daawooyinka ganacsiga sida ezetimibe iyo aprepitant.