Rabeprazole Sodium CAS 117976-90-6 daahirnimo>99.5% (HPLC) Warshada API
Qalabka Kiimikada ee Ruifu Rabeprazole Sodium Dhexdhexaadiyeyaasha
Rabeprazole Sodium CAS 117976-90-6
Rabeprazole Hydroxy Compound CAS 675198-19-3
Rabeprazole Chloride Compound CAS 153259-31-5
Magaca Kiimikada | Rabeprazole Sodium |
La mid ah | 2- ([4- (3-Methoxypropoxy) -3-Methylpyridin-2-yl] methylsulfinyl -1H-Benzo [d] imidazole;Pariprazole |
Lambarka CAS | 117976-90-6 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C18H20N3NaO3S |
Miisaanka Molecular | 381.42 |
Meesha dhalaalaysa | 140.0 ~ 141.0 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Crystal ama budo jaale ah oo cad ilaa waxoogaa cirro ah;Hygroscopic |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
ICP | Wuxuu xaqiijinayaa Qayb Sodium |
Solubility | Si Buuxda Ugu Milmayn Biyaha;Aad ugu milmay Ethanol, Chloroform;Ku milma Methanol |
pH | 9.5-12.0 |
Khasaare xagga qalajinta | <1.00% |
Biraha culus | <20ppm |
Walxaha laxidhiidha | (HPLC) |
Xumaanta A | <0.80% |
wasakhda aan la cayimin | <0.20% |
Wadarta wasakhda | <1.00% |
Xalalka Haraaga ah | (GC) |
Methylene Chloride | <600pm |
Ethanol | <5000pm |
isopropyl Ether | <5000pm |
Acetone | <5000pm |
Xadka Microbial | |
Tirada Aerobe | ≤1000CFU/g |
Caaryada iyo khamiirka ayaa tirinaya | ≤100CFU/g |
E. Coli | Maqan halkii garaam |
Daahirnimada / Habka Falanqaynta | >99.5% (HPLC, Asal qallalan) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API for Anti-Ulcer |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Rabeprazole Sodium (CAS: 117976-90-6) waa matoor bamka proton ah oo xakameynaya wax soo saarka gastric acid ee caloosha.Waxay leedahay dhowr adeegsi oo caafimaad: maaraynta xaaladaha ku lug leh soo saarista aashitada gastric ee xad-dhaafka ah (tusaale Zollinger-Ellison syndrome), xaaladaha ay ka sii daraan aashitada gastric (tusaale boogaha caloosha iyo mindhicirka), iyo xaaladaha la xidhiidha soo-gaadhista muddada dheer ee aashitada gastric (tusaale. calaamadaha cudurka reflux gastroesophageal).Rabeprazole sidoo kale waa mid faa'iido leh oo ay weheliso daawaynta antibiyootiga ee daaweynta cudurka pathogene Helicobacter pylori, taas oo haddii kale ku koraysa jawi acidic ah.Markaa, Rabeprazole Sodium waa FDA loo oggolaaday daawaynta calaamadaha GERD ee dhalinyarada iyo dadka waaweyn, bogsashada boogaha duodenal ee dadka waaweyn, ciribtirka Helicobacter pylori, iyo xaaladaha hypersecretory pathologic.Rabeprazole Sodium waxay xakameysaa soo saarista aashitada caloosha iyadoo la joojinayo gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) ee dusha sirta ah ee unugga caloosha ee caloosha.