Ramelteon Acrylonitrile CAS 196597-79-2 Ramelteon Daahirnimada Dhexdhexaadka ah>98.0% (HPLC)
Soo saaraha iyo alaab-qeybiyaha hormuudka ah, Dhexdhexaadiyeyaasha Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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Magaca Kiimikada | (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene) acetonitrile |
La mid ah | Ramelteon Acrylonitrile;Ramelteon wasakh 6;Ramelteon wasakh B;Ramelteon Cyano wasakhnimo;(E) -2- (6,7-Dihydro-1H-Indeno [5,4-b]furan-8 (2H) -ylidene) acetonitrile;(2E) -2- (1,2,6,7-Tetrahydrocyclopenta[e] [1] benzofuran-8-ylidene) acetonitrile;(1,2,6,7-Tetrahydro-3-oxa-as-indacen-8-ylidene) -acetonitrile |
Lambarka CAS | 196597-79-2 |
Lambarka CAT | RF2886 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C13H11NO |
Miisaanka Molecular | 197.23 |
Meesha dhalaalaysa | 146.0 ~ 151.0 ℃ |
Barta Karsan | 392.1 ± 21.0 ℃ at 760 mmHg |
Barta Fiishka | 165.0 ± 15.9 ℃ |
Cufnaanta | 1.321± 0.06 g/cm3 |
Koodhka HS | 2932999099 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Adag ee Cadaan ilaa Jaalle |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) |
Khasaare xagga qalajinta | <1.00% |
Wadarta wasakhda | <2.00% |
1 H NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadka Ramelteon (CAS: 196597-26-9) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
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(E)-(1,6,7,8-Tetrahydro-2H-Indeno [5,4-b]furan-8-ylidene)acetonitrile (CAS: 935-56-8) waa dhexdhexaadiye Ramelteon (CAS: 196597). -26-9).Ramelteon (TAK-375) waa melatonin receptor agonist oo loogu talagalay dadka MT1 iyo MT2 reseptors iyo qaboojiyeyaasha hore ee maskaxda melatonin ee leh Ki of 14 pM, 112 pM iyo 23.1 pM, siday u kala horreeyaan.Unugyada melatonin waxa la beddelay inta badan iyadoo lagu beddelay nitrogen-ka giraanta indole-ka oo lagu beddelay kaarboon si loo siiyo giraanta indane iyo iyada oo lagu daray kooxda 5-methoxyl ee giraanta indole-ka oo lagu beddelo giraan furan oo adag.Xulashada ramelteon-ka soo baxday ee MT1 reseptor ayaa siddeed jeer ka badan kan MT2 reseptor.Si ka duwan melatonin, way ka waxtar badan tahay bilawga hurdada (firfircoonida MT1) intii ay dib u hagaajin lahayd laxanka wareegga (MT2).Waxay u muuqataa inay si gaar ah uga waxtar badan tahay melatonin laakiin aan waxtar lahayn marka loo eego benzodiazepines sida hypnotic.Muhiimad ahaan, dawadani ma laha wax masuuliyad ah oo la qabatimay (ma aha walaxda la xakameeyey).Natiijo ahaan, dhawaan ayaa loo oggolaaday daaweynta hurdo la'aanta.